A method of removing clot from a vessel, including delivering a clot retrieval device across the clot, wherein the clot retrieval device includes an inner body having a collapsed delivery configuration and an expanded deployed configuration; and an outer body extending along a longitudinal axis and at least partially overlying the inner body. The outer body includes a first scaffolding section, a second scaffolding section hingedly connected distal of the first scaffolding section; the first and second scaffolding sections of the outer body being expandable to a radial extent which is greater than the radial extent of the inner body in the deployed configuration to define a clot reception space between the inner and outer bodies. The method also includes expanding the clot retrieval device; and urging, by the expanding of the first and second scaffolding sections, at least a portion of the clot therebetween.

A catheter that includes storage for an embolic protection device in an accessible, out-of-the-way location within the advancing catheter.

An interventional medical device delivery system comprises a loader provided with a loading tube, a delivery sheath, a dilator, a pushing component, and a hemostasis valve. The loading tube or the delivery sheath is provided with a position-limiting locking connector. An appropriate-rotation control mechanism for controlling a tightening degree between a distal end of the loading tube and a proximal end of the delivery sheath is disposed outside the loading tube or the delivery sheath. The proximal end of the delivery sheath and the distal end of the loading tube engage with each other in a sealed manner, and are threadingly fixed to each other by means of the position-limiting locking connector. The appropriate-rotation control mechanism rotates in one direction to appropriately tighten a thread-connection, and rotates in the opposite direction to release the thread-connection. The interventional medical device conveying system of the invention automatically determines a tightening degree.

A filter comprises an inner, anchoring basket arranged concentrically inside an outer, alignment basket. The anchoring basket comprises a plurality of anchoring struts terminating in barbs. The alignment basket includes a plurality of alignment struts, which terminate downstream of the anchoring struts. A lumen is provided through hubs of the filter so that the filter can be deployed over a guidewire.

An assembly at a proximal end of an intravascular delivery system can allow the proximal end of a pull wire to move independently of a delivery tube. The assembly can generally include the pull wire, the delivery tube, a feature to prevent the proximal end of the pull wire from becoming inaccessible due to distal movement of the pull wire, and a feature to protect the proximal end of the pull wire from inadvertent, premature manipulation. When the intravascular delivery system is navigating tortuous vasculature, the proximal end of the pull wire can move distally in relation to the proximal end of delivery tube, relieving stress on the distal end of the pull wire. The proximal end of the pull wire can be protected from inadvertent manipulation during delivery and made available for manipulation once the distal end of the delivery system is in place.

An intraluminal filtration device for embolic protection includes a device body and each of a coarse filter and a fine filter, for filtering larger-size and smaller-size particles, respectively. The device body includes a body wall extending circumferentially around the longitudinal axis, and being formed at least in part of an organic gel.

An inferior vena cava filter (340) for use in the inferior vena cava (4) to capture thrombus (8) passing through the inferior vena cava (4) towards the heart and lungs to prevent pulmonary embolism comprises a proximal support hoop (302), a distal support hoop (312) and a plurality of support struts (303) extending between the proximal support hoop (302) and the distal support hoop (312). The filter (340) also comprises a plurality of capture arms (121) which are movable from a capturing configuration to an open configuration. The capture arms (121) are biased towards the open configuration. A biodegradable suture holds the capture arms (121) in the capturing configuration.

Devices for delivering and deploying a prosthesis are disclosed and comprise a sheath, a prosthesis disposed within a distal end portion of the sheath, and a wire having a first end coupled to the prosthesis and a second end coupled to the sheath. A body portion of the wire comprises a slack in the wire, and the sheath, prosthesis, and wire are configured so that a proximal movement of the sheath relative to the prosthesis reduces the slack in the wire, and a subsequent proximal movement of the sheath relative to the prosthesis decouples the wire from the prosthesis. Additional devices, systems, and methods are disclosed.

The disclosure pertains to debris diverters for use within the aorta and methods of diverting or redirecting emboli and other debris away from the carotid arteries to prevent cerebral embolization. The disclosure includes aortic diverters positionable in the ascending aorta in order to divert embolic material of all sizes away from the carotid arteries, thereby washing emboli downstream into the thoracic and peripheral vasculature. The debris diverters of the disclosure are adapted to be placed in the ascending and transverse aorta via the left subclavian artery in order to divert embolic material away from the carotid arteries and methods of use therefor.

A detachment and retrieval mechanism for a central venous access filter includes a catheter body, and an outer sheath concentrically disposed about the catheter body. The outer sheath and the catheter body are moveable relative to one another. A filter member includes a first end coupled to the catheter body and a second end movable relative to the catheter body. The first end may have a collar that is immovably coupled to the catheter body in a first state and movably coupled to the catheter body upon transition to a second state.