A method for mechanically capturing and removing a thrombus from a blood vessel includes contacting the thrombus with an inner catheter. A self-expanding body is advanced toward the thrombus, wherein the self-expanding body has a proximal end fixed to a distal end of an elongate catheter. The self-expanding body is preferably made from nickel-titanium and includes a tapered proximal end portion and an open distal end. The self-expanding body preferably has a mesh structure. The self-expanding body is allowed to self-expand in the blood vessel. At least a portion of the thrombus is captured by the self-expanding body and the captured thrombus is then retrieved into a lumen of an aspiration catheter. Negative pressure is applied through the lumen of the aspiration catheter during retrieval of the captured thrombus. A thrombolytic drug may be delivered into the blood vessel before capturing and removing the thrombus.

The invention relates to a safety cartridge (1) for a removable vena cava filter (20), having a proximal end (2) and a distal end (3) and having an inner channel (4) extending between the ends. The cartridge is characterized in that it comprises, on the distal end (3) thereof, a linking device (5) for forming a link with a catheter (30) and, in the inner channel thereof, a projection (6) having a limited size in the axial direction of the cartridge (1) so as to locally reduce the cross-section of the channel (4).

A stent retriever assembly having a proximal end and a distal end, and including a mesh tube having a distal and proximal end, and being connected to a first wire. Also, a blood-porous fragment guard is at the distal end of the mesh tube, the fragment guard including spokes joined at a central hub and extending radially and proximally from the central hub, and wherein a second wire is connected to the central hub so that when the second wire is pulled proximally relative to the first wire, the hub is pulled proximally, causing the spokes to spread out and causing the fragment guard to widen.

Devices, systems and methods for filtering embolic particles that may be generated from a medical procedure including protection of the major branching vessels from the aorta, and catches and filters emboli that may be generated during the TAVR procedure. The filter devices disclosed herein form an improved seal against the vessel wall that is activated by flowing blood. Devices described herein also allow for the closing of the ends of the filter device after capture of emboli, providing further security against accidental loss of emboli post capture.

A medical device (10) for dilating an endovascular lumen and having a collapsed configuration and an expanded configuration, the medical device comprising a stem (20) extending along a longitudinal axis of the device; a first plate (30) disposed partly around the stem (20); a second plate (40) disposed partly around the stem (20) angularly separated in a circumferential direction from the first plate (30); and an expansion mechanism (50) configured to move each of the first plate (30) and/or the second plate (40) radially outwardly when the medical device (10) is expanded from the collapsed configuration to the expanded configuration.

A treatment device (500) is provided including a shaft (507), an expandable member, a first elongated control member (508) and a second elongated control member (502). The expandable member can further include at least a first controllable portion (504) and a second controllable portion (503), where the expandable member, including the first controllable portion and the second controllable portion, is configured to transition between at least a partially retracted configuration and an expanded configuration under control of at least the first elongated control member (508). Further still, the first controllable portion can be configured to transition between at least a partially retracted configuration and an expanded configuration, while the second controllable portion (503) is configured to remain substantially unchanged, under control of at least the second elongated control member (502).

A device for retrieval of a vena cava filter is provided. The retrieval device has, approximately, an umbrella shape and consists of a central shaft; a plurality of frame struts, attached to frame strut attachment points on the central shaft and disposed radially about the central shaft; and a plurality of snare wires. The retrieval device has a collapsed configuration for insertion and removal from a blood vessel of a patient and an expanded state for capturing an intravascular filter in the blood vessel of the patient. The plurality of snare wires provides multiple points at which a vena cava filter, particularly one that has become misaligned during deployment or treatment, can be caught. The frame struts can be substantially sinusoidal in shape and made of shape memory metal, such as Nitinol. The snare wires can be made of a biocompatible material such as silk, polyester, polypropylene, or nylon.

Catheter-delivered endovascular medical devices are described. The devices may include a pull wire attached to a deployable dual basket system. The deployable dual basket system may include a proximal basket and a distal basket that are connected by basket connector tether memory metal strips that rotate/twist relative to the longitudinal axes of the basket and form flex points of the system. The proximal basket and the distal basket may be comprised of a plurality of cells and the proximal basket may taper at its proximal end and the distal basket may be tapered at its distal end. Methods of using and making the devices are also described.

A treatment method and medical device are disclosed for cutting a substance inside a body lumen. The medical device for cutting substances inside a body lumen, the medical device including a rotatable tubular drive shaft; a treatment member connected to a distal side of the drive shaft; an elongated tube extending through the drive shaft; and a bearing member connecting a distal side of the treatment member and the elongated tube.

A medical grasping device is disclosed. The medical grasping device may be configured to retrieve an object from within a body lumen. A medical grasping device assembly, wherein a portion of the medical grasping device is disposed within a lumen of a delivery sheath, and methods of using the medical grasping device assembly are also disclosed.