Intraocular lenses that include a central portion and one or more peripheral portions. The IOLs includes a sensor housing and a communication member, both of which are secured to the central portion.

A lens including a flexible refractive optic having a fixed refractive index, an electro-active element embedded within the flexible refractive optic, wherein the electro-active element has an alterable refractive index, and a controller electrically connected to the electro-active element wherein when power is applied thereto the refractive index of the electro-active element is altered.

Disclosed is an optical cylinder of a corneal prosthesis comprising: a) an optical cylinder comprising a solid polymer, and b) a plurality of nanoparticles forming a substantially uniform layer on a circumference of the solid polymer surface of the optical cylinder. Also disclosed are methods of surface treatment of optical cylinders of corneal prostheses, and corneal prostheses thereof.

The invention relates to novel methods for making transparent and curved stromal cell tissues and decellularized forms thereof. Novel tissues are also provided.

Described are polymerizable high energy light absorbing compounds of formula I:

##STR00001##

wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, R.sup.9, and X are as described herein. The compounds absorb various wavelengths of ultraviolet and/or high energy visible light and are suitable for incorporation in various products, such as biomedical devices and ophthalmic devices.

A method (100) of forming an ocular prosthesis (13) comprising: receiving (102a) three dimensional scan data of a patients eye, the three dimensional scan data including volumetric data of at least an iris region, a pupil region and a cornea region of the eye; and forming (110) an ocular prosthesis (13) by an additive manufacturing process, the ocular prosthesis (13) having a body (15) with a volume, wherein the body of the prosthesis includes a three dimensional iris region (23), a three dimensional pupil region (25) and a three dimensional cornea region (26), and the volumetric data determines the size and shape of the iris region (23), the pupil region (25) and the cornea region (26) of the prosthesis (13).

A dissection system for corneal transplants includes a housing including a contact side to be positioned against a cornea. The housing includes an interior passageway with an opening at the contact side. The dissection system includes a blade assembly disposed in the interior passageway. The blade assembly includes a first blade and a second blade. The first blade includes a first cutting edge and the second blade includes a second cutting edge. The first blade and the second blade are movable relative to the housing such that the first cutting edge and the second cutting edge extend through the opening of the housing and out of the interior passageway. The first cutting edge produces a first cut in the cornea. The second cutting edge produces a second cut in the cornea. The first cut and the second cut define a volume of tissue for removal from the cornea.

Methods and systems wherein laser induced refractive index changes by focused femtosecond laser pulses in optical polymeric materials or optical tissues is performed to address various types of vision correction.

A prosthetic capsular device configured to be inserted in an eye after removal of a lens, in some embodiments, can comprise a housing structure comprising capable of containing an intraocular device and an equiconvex refractive surface. The housing structure can comprise an anterior portion comprising an anterior opening, a posterior portion comprising a posterior opening, and a continuous lateral portion between the anterior portion and the posterior portion.

A lens including a flexible refractive optic having a fixed refractive index, an electro-active element embedded within the flexible refractive optic, wherein the electro-active element has an alterable refractive index, and a controller electrically connected to the electro-active element wherein when power is applied thereto the refractive index of the electro-active element is altered.