The present disclosure provides methods and systems for receiving, with processing circuitry of an implant device, an electrical signal from a free tissue graft attached to a portion of a nerve (e.g., a nerve branch or fascicle) through an electrical conductor in electrical communication with the free tissue graft (e.g., muscle graft), the nerve having reinnervated the free tissue graft. The electrical signal from the free tissue graft has a voltage amplitude of greater than or equal to about 150 microvolts. The processing circuitry stores signal data corresponding to the electrical signal from the free tissue graft in a memory accessible to the processing circuitry.

One aspect of the present disclosure relates to a method for controlling levels of perceived intensity of a sensory stimulus. The method includes configuring a stimulation signal with an activation charge rate (ACR) based on a predefined level of intensity by a subject during an action. The ACR is based on a strength of pulses in the stimulation signal parameter and a frequency of pulses in the stimulation signal parameter. The stimulation signal can be applied to neural tissue of a subject during the action. Based on the stimulation signal, the subject can be induced to perceive the predefined level of intensity during the action.

A device for carrying out mirror therapy includes: a camera for filming a healthy limb of a patient, a work surface on which the patient positions his healthy limb or affected limb, a screen for displaying the image of the healthy limb which is positioned on the work surface and which is filmed by the camera, the screen preventing the patient from directly seeing his healthy limb or affected limb on the work surface, and a support structure which is connected to the work surface and on which the screen and the camera are mounted. The device has a mirror fixed behind the screen. The camera films the healthy limb reflected in the mirror, and the image displayed by the screen is a reflection of the healthy limb in the mirror.

Methods and systems to interface between physiological devices and a prosthetic device, including to receive a plurality of types of physiological activity signals from a user, decode a user movement intent from each of the plurality of signals types, and fuse the movement intents into a joint decision to control moveable elements of the prosthetic device.

Methods for sensing or stimulating electrical activity of brain tissue from within an animal vessel by placement of an intravascular device within an animal vessel to control an external device, the intravascular device being adapted to at least one of sense and stimulate activity of brain tissue located outside the vessel proximate the intravascular device.

The present disclosure provides methods and systems for receiving, with processing circuitry of an implant device, an electrical signal from a free tissue graft attached to a portion of a nerve (e.g., a nerve branch or fascicle) through an electrical conductor in electrical communication with the free tissue graft (e.g., muscle graft), the nerve having reinnervated the free tissue graft. The electrical signal from the free tissue graft has a voltage amplitude of greater than or equal to about 150 microvolts. The processing circuitry stores signal data corresponding to the electrical signal from the free tissue graft in a memory accessible to the processing circuitry.

The present disclosure provides methods and systems for receiving, with processing circuitry of an implant device, an electrical signal from a free tissue graft attached to a portion of a nerve (e.g., a nerve branch or fascicle) through an electrical conductor in electrical communication with the free tissue graft (e.g., muscle graft), the nerve having reinnervated the free tissue graft. The electrical signal from the free tissue graft has a voltage amplitude of greater than or equal to about 150 microvolts. The processing circuitry stores signal data corresponding to the electrical signal from the free tissue graft in a memory accessible to the processing circuitry.

The present invention relates to a prosthesis for an arm or a leg, comprising a flexible sleeve for receiving a residual limb, a constrictor on the flexible sleeve for tightening the sleeve around the residual limb, and a rigid mount secured to the sleeve and spaced axially along the sleeve from the constrictor for mounting a tool. A sensor is provided in the mount to measure a physical parameter associated with the function performed by the tool. The prosthesis further comprises an actuator connected to the constrictor and a control circuit acting on the actuator to vary the force tightening the sleeve around the residual limb in dependence upon the measured parameter.

Methods for sensing or stimulating electrical activity of brain tissue from within an animal vessel by placement of an intravascular device within an animal vessel to control an external device, the intravascular device being adapted to at least one of sense and stimulate activity of brain tissue located outside the vessel proximate the intravascular device.

Sensory information can be delivered to a subject mammal, for example, for restoring a sense of cutaneous touch and limb motion to the subject mammal. A biomimetic electrical signal is generated based on (a) a stimulation reference signal applied to a somatosensory region of a nervous system of a reference mammal, (b) a stimulated-response signal acquired from a sensory cortex of the reference mammal in response to application of the stimulation reference signal to the thalamic nucleus, and (c) a natural-response signal acquired from the sensory cortex in response to peripheral touch stimuli and/or peripheral nerve stimulation of the reference mammal. The biomimetic electrical signal is applied to a somatosensory region of a nervous system of the subject mammal to induce an activation response, in a sensory cortex of the subject mammal.