Patent classifications
C07C309/14
CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS
The present disclosure provides one or more amino lipids such as an amino lipids containing a sulfonic acid or sulfonic acid derivative of the formulas:
##STR00001##
wherein the variables are as defined herein. These amino lipids may be used in compositions with one or more helper lipids and a nucleic acid therapeutic agent. These compositions may be used to treat a disease or disorder such as cancer, cystic fibrosis, or other genetic diseases.
CLEAVABLE SURFACTANTS
The invention provides surfactant compounds of formulas I-IX, which can be used in methods for aiding the solubilization, digestion, preparation, analysis, and/or characterization of biological material, for example, proteins or cell membranes. The compounds can also aid in the recovery of peptides generated during protein digestion, particularly for in-gel digestion protocol. Additionally, the compounds can improve enzymatic protein deglycosylation without interfering with downstream sample preparation steps and mass spectrometric analysis. The compounds can be specifically useful as digestion aids that can be decomposed by an acid, by heat, or a combination thereof. Decomposition of the surfactants allows for facile separation from isolated samples, and/or allows for analysis of the sample without interfering with the sensitivity of various analytical techniques.
CLEAVABLE SURFACTANTS
The invention provides surfactant compounds of formulas I-IX, which can be used in methods for aiding the solubilization, digestion, preparation, analysis, and/or characterization of biological material, for example, proteins or cell membranes. The compounds can also aid in the recovery of peptides generated during protein digestion, particularly for in-gel digestion protocol. Additionally, the compounds can improve enzymatic protein deglycosylation without interfering with downstream sample preparation steps and mass spectrometric analysis. The compounds can be specifically useful as digestion aids that can be decomposed by an acid, by heat, or a combination thereof. Decomposition of the surfactants allows for facile separation from isolated samples, and/or allows for analysis of the sample without interfering with the sensitivity of various analytical techniques.
SYSTEM FOR SYSTEM FOR PREPARING HIGH-PURITY TAURINE AND SALT
A system for preparing high-purity taurine and salt. The system can be used in an ethylene oxide process for producing taurine. The system includes an addition reaction device, an ammonolysis reaction device, an evaporation device, and a taurine salt concentrated solution collection device. The ammonolysis reaction device is provided with a metal salt inlet, the taurine salt concentrated solution collection device is connected with an ion exchange system for ion exchange, the ion exchange system is provided with an acid inlet, an adsorption solution outlet and an eluate outlet, the adsorption solution outlet of the ion exchange system is connected with a taurine extraction device, the eluate outlet of the ion exchange system is connected with a salt extraction device, and the ion exchange system is provided with a purified water inlet, an adsorption unit cleaning water outlet and an elution unit cleaning water outlet.
SYSTEM FOR SYSTEM FOR PREPARING HIGH-PURITY TAURINE AND SALT
A system for preparing high-purity taurine and salt. The system can be used in an ethylene oxide process for producing taurine. The system includes an addition reaction device, an ammonolysis reaction device, an evaporation device, and a taurine salt concentrated solution collection device. The ammonolysis reaction device is provided with a metal salt inlet, the taurine salt concentrated solution collection device is connected with an ion exchange system for ion exchange, the ion exchange system is provided with an acid inlet, an adsorption solution outlet and an eluate outlet, the adsorption solution outlet of the ion exchange system is connected with a taurine extraction device, the eluate outlet of the ion exchange system is connected with a salt extraction device, and the ion exchange system is provided with a purified water inlet, an adsorption unit cleaning water outlet and an elution unit cleaning water outlet.
SELF-DIVERTING ACIDIZING SYSTEM
A method of acidizing a formation penetrated by a wellbore that includes the steps of injecting into the wellbore at a pressure below formation fracturing pressure a treatment fluid that includes a gelling fluid including a gelling agent and a hydrophobically-modified associative polymer, and an aqueous acid; and allowing the treatment fluid to acidize the formation.
SELF-DIVERTING ACIDIZING SYSTEM
A method of acidizing a formation penetrated by a wellbore that includes the steps of injecting into the wellbore at a pressure below formation fracturing pressure a treatment fluid that includes a gelling fluid including a gelling agent and a hydrophobically-modified associative polymer, and an aqueous acid; and allowing the treatment fluid to acidize the formation.
Fatty amines, amidoamines, and their derivatives from natural oil metathesis
Fatty amine compositions made from a metathesis-derived C10-C17 monounsaturated acid, octadecene-1,18-dioic acid, or their ester derivatives are disclosed. In another aspect, fatty amidoamines made by reacting a metathesis-derived C10-C17 monounsaturated acid, octadecene-1,18-dioic acid, or their ester derivatives with an aminoalkyl-substituted tertiary amine are disclosed. The fatty amines or amidoamines are advantageously sulfonated, sulfitated, oxidized, or reduced. In other aspects, the ester derivative is a modified triglyceride made by self-metathesis of a natural oil or an unsaturated triglyceride made by cross-metathesis of a natural oil with an olefin.
Fatty amines, amidoamines, and their derivatives from natural oil metathesis
Fatty amine compositions made from a metathesis-derived C10-C17 monounsaturated acid, octadecene-1,18-dioic acid, or their ester derivatives are disclosed. In another aspect, fatty amidoamines made by reacting a metathesis-derived C10-C17 monounsaturated acid, octadecene-1,18-dioic acid, or their ester derivatives with an aminoalkyl-substituted tertiary amine are disclosed. The fatty amines or amidoamines are advantageously sulfonated, sulfitated, oxidized, or reduced. In other aspects, the ester derivative is a modified triglyceride made by self-metathesis of a natural oil or an unsaturated triglyceride made by cross-metathesis of a natural oil with an olefin.
COMPOSITION FOR POLYMERIZATION, METHOD FOR PRODUCING SAME, COMPOSITION FOR A COATING CONTAINING COMPOSITION FOR POLYMERIZATION, METHOD FOR PRODUCING COMPOSITION FOR A COATING USING COMPOSITION FOR POLYMERIZATION, AND METHOD FOR PRODUCING COATING
A composition for polymerization, which can improve the storage stability in a high-temperature environment when a specific sulfobetaine monomer is stored as powder and can inhibit the discoloration of a cured film when the monomer is made into a cured film, and a method for producing the composition for polymerization: a composition for a coating containing the composition for polymerization, a method for producing the composition for a coating using the composition for polymerization, and a method for producing a coating; the composition for polymerization contains a monomer represented by formula (I) and water, in which the moisture content is equal to or higher than 3% by mass and less than 10% by mass.
##STR00001## (R represents a hydrogen atom or a methyl group.)