C07D207/327

Benzoylglycine derivatives and methods of making and using same

Disclosed are compounds of formulae: and pharmaceutically acceptable salts thereof, wherein the variables, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.11, R.sub.12, R.sub.13, R.sub.14, R.sub.15, R.sub.16, R.sub.17, n, and m are defined herein. These compounds are useful for treating Gram-negative bacteria infections. Also disclosed are methods of making these compounds. ##STR00001##

COMPOSITIONS FOR THE TREATMENT OF PULMONARY FIBROSIS
20210130301 · 2021-05-06 · ·

The present invention relates to compounds and their use in the prophylactic and/or therapeutic treatment of pulmonary fibrosis and/or related conditions.

COMPOSITIONS FOR THE TREATMENT OF PULMONARY FIBROSIS
20210130301 · 2021-05-06 · ·

The present invention relates to compounds and their use in the prophylactic and/or therapeutic treatment of pulmonary fibrosis and/or related conditions.

Thiocarbonylthio compounds as chain transfer agents suitable for raft polymerization

The present invention relates to a compound having the structure of formula (I), wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, and R.sup.7 are as described herein. The present invention also relates to a process for the preparation of a compound of formula (I) and to a process for the synthesis of a polymer using the compound of formula (I) through controlled free radical polymerization. ##STR00001##

Thiocarbonylthio compounds as chain transfer agents suitable for raft polymerization

The present invention relates to a compound having the structure of formula (I), wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, and R.sup.7 are as described herein. The present invention also relates to a process for the preparation of a compound of formula (I) and to a process for the synthesis of a polymer using the compound of formula (I) through controlled free radical polymerization. ##STR00001##

Grp94 selective inhibitors and uses thereof

The present technology provides compounds according to Formula I or Formula III as well as compositions including such compounds useful for the treatment of metastatic cancer and/or glaucoma. ##STR00001##

Compositions for the treatment of pulmonary fibrosis
10919863 · 2021-02-16 · ·

The present invention relates to compounds and their use in the prophylactic and/or therapeutic treatment of pulmonary fibrosis and/or related conditions.

Compositions for the treatment of pulmonary fibrosis
10919863 · 2021-02-16 · ·

The present invention relates to compounds and their use in the prophylactic and/or therapeutic treatment of pulmonary fibrosis and/or related conditions.

Benzoylglycine Derivatives and Methods of Making and Using Same

Disclosed are compounds of formulae:

##STR00001##

and pharmaceutically acceptable salts thereof, wherein the variables, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.11, R.sub.12, R.sub.13, R.sub.14, R.sub.15, R.sub.16, R.sub.17, n, and m are defined herein. These compounds are useful for treating Gram-negative bacteria infections. Also disclosed are methods of making these compounds.

Benzoylglycine Derivatives and Methods of Making and Using Same

Disclosed are compounds of formulae:

##STR00001##

and pharmaceutically acceptable salts thereof, wherein the variables, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.11, R.sub.12, R.sub.13, R.sub.14, R.sub.15, R.sub.16, R.sub.17, n, and m are defined herein. These compounds are useful for treating Gram-negative bacteria infections. Also disclosed are methods of making these compounds.