The present invention discloses the preparation method of cis-p-menthane-1,8-di-secondary amine compounds and their application in weed control. The preparation method is as follows: cis-p-menthane-1,8-di-Schiff base compounds are used as the raw material, and the reducing agent is added in batches into the raw material in a polar organic solvent at −10˜50° C. to react for 1˜24 h; after the reaction is complete, the reaction solution is quenched with distilled water and extracted with dichloromethane, and the extract phase is dried with anhydrous sodium sulfate, filtered with a filter and then distilled under reduced pressure to obtain crude cis-p-menthane-1,8-di-secondary amine compounds, which are purified into the pure product through recrystallization or silica gel column chromatography. The Petri dish seed germination method is used to determine the root and stem growth inhibition levels of barnyard grass incubated under different concentrations of cis-p-menthane-1,8-di-secondary amine compounds to evaluate the herbicidal activity of the compounds.

The instant invention describes compounds having IL-6 modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by IL-6.

The instant invention describes compounds having IL-6 modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by IL-6.

The present invention discloses a phosphine free cobalt based catalyst of formula (I) and a process for preparation thereof. The present invention further discloses a process for the synthesis of aromatic heterocyclic compounds of formula (II) and pyrazine derivative using the phosphine free cobalt based catalyst of formula (I).

The present invention discloses a phosphine free cobalt based catalyst of formula (I) and a process for preparation thereof. The present invention further discloses a process for the synthesis of aromatic heterocyclic compounds of formula (II) and pyrazine derivative using the phosphine free cobalt based catalyst of formula (I).

A cyclopropylamine compound as a lysine-specific demethylase 1 (LSD1) inhibitor. Particularly, the present invention relates to a compound represented by formula (I) and a pharmaceutically acceptable salt thereof. The present invention also provides an application of the same in preparing a drug for treating an LSD1-related disease.

##STR00001##

A cyclopropylamine compound as a lysine-specific demethylase 1 (LSD1) inhibitor. Particularly, the present invention relates to a compound represented by formula (I) and a pharmaceutically acceptable salt thereof. The present invention also provides an application of the same in preparing a drug for treating an LSD1-related disease.

##STR00001##

Disclosed is a compound containing a specific structure having an azomethine part, the compound being reversibly fluidized and non-fluidized by being irradiated with light.

Disclosed is a compound containing a specific structure having an azomethine part, the compound being reversibly fluidized and non-fluidized by being irradiated with light.

Methods for deposition of elemental metal films on surfaces using metal coordination complexes comprising nitrogen-containing ligands are provided. Also provided are nitrogen-containing ligands useful in the methods of the invention and metal coordination complexes comprising these ligands.