Patent classifications
C07D209/24
PSMA-targeting compounds and uses thereof
Compositions and methods for visualizing tissue under illumination with near-infrared radiation, including compounds comprising near-infrared, closed chain, sulfo-cyanine dyes and prostate specific membrane antigen ligands are disclosed.
PSMA-targeting compounds and uses thereof
Compositions and methods for visualizing tissue under illumination with near-infrared radiation, including compounds comprising near-infrared, closed chain, sulfo-cyanine dyes and prostate specific membrane antigen ligands are disclosed.
COMPOUNDS AND METHODS OF USE THEREOF
Indole compounds are disclosed. Also disclosed are methods for using the compounds to treat human and animal disease, pharmaceutical compositions of the compounds, and kits including the compounds.
COMPOUNDS AND METHODS OF USE THEREOF
Indole compounds are disclosed. Also disclosed are methods for using the compounds to treat human and animal disease, pharmaceutical compositions of the compounds, and kits including the compounds.
Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof
- David Weninger Barnes ,
- Gregory Raymond Bebernitz ,
- Kevin Clairmont ,
- Scott Louis Cohen ,
- Robert Edson Damon, II ,
- Robert Francis Day ,
- Stephanie Kay Dodd ,
- Christoph Gaul ,
- Hatice Belgin Gulgeze Efthymiou ,
- Monish Jain ,
- Rajeshri Ganesh Karki ,
- Louise Clare Kirman ,
- Kai Lin ,
- Justin Yik Ching Mao ,
- Tajesh Jayprakash Patel ,
- Brian Kenneth Raymer ,
- Su Liansheng
The present invention provides compounds of formula (IV); ##STR00001##
or pharmaceutically acceptable salts thereof, wherein the variables are defined as herein. The present invention provides a method for manufacturing the compounds of formula (IV), their therapeutic uses, combinations with other of pharmacologically active agents, and a pharmaceutical compositions.
Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof
- David Weninger Barnes ,
- Gregory Raymond Bebernitz ,
- Kevin Clairmont ,
- Scott Louis Cohen ,
- Robert Edson Damon, II ,
- Robert Francis Day ,
- Stephanie Kay Dodd ,
- Christoph Gaul ,
- Hatice Belgin Gulgeze Efthymiou ,
- Monish Jain ,
- Rajeshri Ganesh Karki ,
- Louise Clare Kirman ,
- Kai Lin ,
- Justin Yik Ching Mao ,
- Tajesh Jayprakash Patel ,
- Brian Kenneth Raymer ,
- Su Liansheng
The present invention provides compounds of formula (IV); ##STR00001##
or pharmaceutically acceptable salts thereof, wherein the variables are defined as herein. The present invention provides a method for manufacturing the compounds of formula (IV), their therapeutic uses, combinations with other of pharmacologically active agents, and a pharmaceutical compositions.
PSMA TARGETED FLUORESCENT AGENTS FOR IMAGE GUIDED SURGERY
Compositions and methods for visualizing tissue under illumination with near-infrared radiation, including compounds comprising near-infrared, closed chain, sulfo-cyanine dyes and prostate specific membrane antigen ligands are disclosed.
PSMA TARGETED FLUORESCENT AGENTS FOR IMAGE GUIDED SURGERY
Compositions and methods for visualizing tissue under illumination with near-infrared radiation, including compounds comprising near-infrared, closed chain, sulfo-cyanine dyes and prostate specific membrane antigen ligands are disclosed.
PSMA TARGETED FLUORESCENT AGENTS FOR IMAGE GUIDED SURGERY
Compositions and methods for visualizing tissue under illumination with near-infrared radiation, including compounds comprising near-infrared, closed chain, sulfo-cyanine dyes and prostate specific membrane antigen ligands are disclosed.
PSMA-targeting compounds and uses thereof
Prostate-specific membrane antigen (PSMA) targeting compounds are described. Uses of the compounds for imaging, therapy, cell sorting, and tumor mapping are also described.