This invention relates to 4-substituted phenylamine derivatives of the general formula (I), wherein R.sup.1 to R.sup.8 and A have the meanings as defined in description. The invention further relates to methods for their preparation and use of said compounds to fight undesired phytopathogenic microorganisms, and agents for said purpose, comprising said phenylamine derivatives, all according to the invention. This invention further relates to a method for fighting undesired phytopathogenic microorganisms by application of said 4-substituted phenylamine derivatives of general formula (I) to such undesired microorganisms and/or to their habitat, according to the invention.

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This invention relates to 4-substituted phenylamine derivatives of the general formula (I), wherein R.sup.1 to R.sup.8 and A have the meanings as defined in description. The invention further relates to methods for their preparation and use of said compounds to fight undesired phytopathogenic microorganisms, and agents for said purpose, comprising said phenylamine derivatives, all according to the invention. This invention further relates to a method for fighting undesired phytopathogenic microorganisms by application of said 4-substituted phenylamine derivatives of general formula (I) to such undesired microorganisms and/or to their habitat, according to the invention.

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The present invention relates to an anhydrosugar alcohol composition having enhanced storage stability, and an anhydrosugar alcohol storage method, and more specifically, to an anhydrosugar alcohol composition having enhanced storage stability by comprising anhydrosugar alcohol and an amine-based additive; and to a method by which anhydrosugar alcohol having excellent quality may be provided by having the storing of the anhydrosugar alcohol performed under the existence of the amine-based additive, thereby remarkably enhancing the storage stability of the anhydrosugar alcohol.

The present invention relates to certain pharmaceutically acceptable salts of (S)-3-(2,5-dimethoxy-4-(trifluoromethyl)phenyl)piperidine and (S)-3-(2-methoxy-5-(methylthio)-4-(trifluoromethyl) phenyl)piperidine and specific polymorphs thereof. More particularly, the present invention relates to the compounds of Formula (VI) as well as chemical routes for their manufacture.

The present invention relates to certain pharmaceutically acceptable salts of (S)-3-(2,5-dimethoxy-4-(trifluoromethyl)phenyl)piperidine and (S)-3-(2-methoxy-5-(methylthio)-4-(trifluoromethyl) phenyl)piperidine and specific polymorphs thereof. More particularly, the present invention relates to the compounds of Formula (VI) as well as chemical routes for their manufacture.

Disclosed are methods for separating, recovering, and purifying CBGA, CBDVA, THCVA, CBCVA, and CBCA from dewatered and desolventized crude complex extracts or mixtures of metabolites, cannabinoids, and Cannabis phytochemicals. The methods comprise solubilizing the extracts or mixtures of cannabinoids in a selected solvent, adding a selected amine to precipitate a CBGA-amine or CBDVA-amine or THCVA-amine or CBCVA-amine or CBCA-amine salt therefrom, dissolving the recovered amine salt in a selected solvent, and adding a selected antisolvent to recrystallize a purified amine salt therefrom. The recrystallized amine salt may be decarboxylated to form a mixture of CBG or CBDV or THCV or CBCV or CBC and amine. The cannabinoid and amine mixture may be acidified to separate the amine from CBG or CBDV or THCV or CBCV or CBC. The recovered CBG or CBDV or THCV or CBCV or CBC may then be concentrated.

Disclosed are methods for separating, recovering, and purifying CBGA, CBDVA, THCVA, CBCVA, and CBCA from dewatered and desolventized crude complex extracts or mixtures of metabolites, cannabinoids, and Cannabis phytochemicals. The methods comprise solubilizing the extracts or mixtures of cannabinoids in a selected solvent, adding a selected amine to precipitate a CBGA-amine or CBDVA-amine or THCVA-amine or CBCVA-amine or CBCA-amine salt therefrom, dissolving the recovered amine salt in a selected solvent, and adding a selected antisolvent to recrystallize a purified amine salt therefrom. The recrystallized amine salt may be decarboxylated to form a mixture of CBG or CBDV or THCV or CBCV or CBC and amine. The cannabinoid and amine mixture may be acidified to separate the amine from CBG or CBDV or THCV or CBCV or CBC. The recovered CBG or CBDV or THCV or CBCV or CBC may then be concentrated.

In some aspects, the present disclosure provides methods of aminating an aromatic compound comprising reacting an aminating agent with an aromatic compound in the presence of a rhodium catalyst. In some embodiments, the methods may comprise aminating an aromatic compound which contains multiple different functional groups. The methods described herein may also be used to create bicyclic system comprising reacting an intramolecular aminating agent with an aromatic ring to obtain a second ring containing a nitrogen atom. In another aspect, the methods described herein may also be used to create a cyclic aliphatic cyclic/poly cyclic amine system comprising a reacting an intramolecular aminating agent by insertion into a C(sp3)-H bond.

To provide a compound having an effect for preventing photolysis of a liquid crystal composition, and having a high solubility in the liquid crystal composition, a liquid crystal composition containing the compound, and a liquid crystal display device including the composition. The compound is represented by formula (1), the liquid crystal composition contains the compound, and the liquid crystal display device includes the composition. ##STR00001## In formula (1), R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are independently hydrogen or alkyl having 1 to 4 carbons; ring A.sup.1 and ring A.sup.2 are independently 1,4-cyclohexylene, 1,4-phenylene or the like; Z.sup.1, Z.sup.2 and Z.sup.3 are independently a single bond, alkylene or the like; and n is 0, 1 or 2.

To provide a compound having an effect for preventing photolysis of a liquid crystal composition, and having a high solubility in the liquid crystal composition, a liquid crystal composition containing the compound, and a liquid crystal display device including the composition. The compound is represented by formula (1), the liquid crystal composition contains the compound, and the liquid crystal display device includes the composition. ##STR00001## In formula (1), R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are independently hydrogen or alkyl having 1 to 4 carbons; ring A.sup.1 and ring A.sup.2 are independently 1,4-cyclohexylene, 1,4-phenylene or the like; Z.sup.1, Z.sup.2 and Z.sup.3 are independently a single bond, alkylene or the like; and n is 0, 1 or 2.