C07D213/57

Organic compound, and organic light emitting diode and organic light emitting display device including the same

An embodiment of the present invention provides an organic compound represented by following Formula: ##STR00001##
wherein each of R.sub.1 to R.sub.14 is independently selected from hydrogen, substituted or non-substituted C.sub.6 to C.sub.12 aryl, substituted or non-substituted C.sub.3 to C.sub.11 heteroaryl, substituted or non-substituted C.sub.1 to C.sub.10 alkyl, substituted or non-substituted C.sub.1 to C.sub.10 alkoxy, ether, cyano group (CN), fluorine, tri-fluoro methyl, tri-fluoro methoxy and trimethylsilyl, and at least one of R.sub.1 to R.sub.10 is the cyano group, and wherein at least one of R.sub.11 to R.sub.14 is the cyano group, and A is selected from substituted or non-substituted C.sub.6 to C.sub.30 aryl and substituted or non-substituted C.sub.3 to C.sub.30 heteroaryl. The present invention also provides an organic light emitting diode and an organic light emitting display device including the organic compound.

Organic compound, and organic light emitting diode and organic light emitting display device including the same

An embodiment of the present invention provides an organic compound represented by following Formula: ##STR00001##
wherein each of R.sub.1 to R.sub.14 is independently selected from hydrogen, substituted or non-substituted C.sub.6 to C.sub.12 aryl, substituted or non-substituted C.sub.3 to C.sub.11 heteroaryl, substituted or non-substituted C.sub.1 to C.sub.10 alkyl, substituted or non-substituted C.sub.1 to C.sub.10 alkoxy, ether, cyano group (CN), fluorine, tri-fluoro methyl, tri-fluoro methoxy and trimethylsilyl, and at least one of R.sub.1 to R.sub.10 is the cyano group, and wherein at least one of R.sub.11 to R.sub.14 is the cyano group, and A is selected from substituted or non-substituted C.sub.6 to C.sub.30 aryl and substituted or non-substituted C.sub.3 to C.sub.30 heteroaryl. The present invention also provides an organic light emitting diode and an organic light emitting display device including the organic compound.

Thioamides and amides for controlling animal pests

The invention relates to the use of a compound of formula (I) ##STR00001##
or a salt thereof for combating animal pests,
where the symbols and indices are defined in the specification.

Thioamides and amides for controlling animal pests

The invention relates to the use of a compound of formula (I) ##STR00001##
or a salt thereof for combating animal pests,
where the symbols and indices are defined in the specification.

Amyloid targeting agents and methods of using the same

Provided herein is the design and synthesis of novel molecular rotor fluorophores useful for detection of amyloid or amyloid like proteins. The fluorophores are designed to exhibit enhanced fluorescence emission upon associating with amyloid or amyloid like proteins as compared to unbound compound. Also disclosed herein are methods for treating diseases associated with amyloid or amyloid like proteins.

Amyloid targeting agents and methods of using the same

Provided herein is the design and synthesis of novel molecular rotor fluorophores useful for detection of amyloid or amyloid like proteins. The fluorophores are designed to exhibit enhanced fluorescence emission upon associating with amyloid or amyloid like proteins as compared to unbound compound. Also disclosed herein are methods for treating diseases associated with amyloid or amyloid like proteins.

GUANIDINE DERIVATIVE AND MEDICAL USE THEREOF

A compound has a guanidine skeleton that inhibits the protease activity of MALT1 and exerts a therapeutic or prophylactic effect on autoimmune disease such as psoriasis or allergic disease such as atopic dermatitis. The guanidine derivative is typified by the following formula or a pharmacologically acceptable salt thereof.

##STR00001##

GUANIDINE DERIVATIVE AND MEDICAL USE THEREOF

A compound has a guanidine skeleton that inhibits the protease activity of MALT1 and exerts a therapeutic or prophylactic effect on autoimmune disease such as psoriasis or allergic disease such as atopic dermatitis. The guanidine derivative is typified by the following formula or a pharmacologically acceptable salt thereof.

##STR00001##

SUBSTITUTED CYCLOHEXANES AS MUSCARINIC M1 RECEPTOR AND/OR M4 RECEPTOR AGONISTS

This invention relates to compounds that are agonists of the muscarinic M.sub.1 receptor or M.sub.1 and M.sub.4 receptors and which are useful in the treatment of muscarinic M.sub.1 or M.sub.1/M.sub.4 receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds provided are of formula

##STR00001##

wherein Q.sup.4, Q.sup.5, R.sup.5, p, V, Q.sup.1, Q.sup.2, X.sup.1, X.sup.2 and W are defined herein.

SUBSTITUTED CYCLOHEXANES AS MUSCARINIC M1 RECEPTOR AND/OR M4 RECEPTOR AGONISTS

This invention relates to compounds that are agonists of the muscarinic M.sub.1 receptor or M.sub.1 and M.sub.4 receptors and which are useful in the treatment of muscarinic M.sub.1 or M.sub.1/M.sub.4 receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds provided are of formula

##STR00001##

wherein Q.sup.4, Q.sup.5, R.sup.5, p, V, Q.sup.1, Q.sup.2, X.sup.1, X.sup.2 and W are defined herein.