Patent classifications
C07D213/73
Bridged bicyclic kallikrein inhibitors
Provided herein are kallikrein modulating compounds, pharmaceutical compositions comprising the same, and uses thereof.
Bridged bicyclic kallikrein inhibitors
Provided herein are kallikrein modulating compounds, pharmaceutical compositions comprising the same, and uses thereof.
Benzylamine derivatives and their utility as cholesterol ester-transfer protein inhibitors
The present invention provides, among other things, new benzylamine compounds, compositions comprising benzylamine compounds, methods of making benzylamine compounds, and methods of using benzylamine compounds for treating or preventing a variety of conditions or diseases associated with lipoprotein metabolism.
Benzylamine derivatives and their utility as cholesterol ester-transfer protein inhibitors
The present invention provides, among other things, new benzylamine compounds, compositions comprising benzylamine compounds, methods of making benzylamine compounds, and methods of using benzylamine compounds for treating or preventing a variety of conditions or diseases associated with lipoprotein metabolism.
METHOD OF REDUCING AROMATIC NITRO COMPOUNDS
A method for reducing a substrate selected from 2-methyl-5-nitropyridine and methyl 4-(2-fluoro-3-nitrobenzyl)piperazine-1-carboxylate is provided catalysed by a nitroreductase and a disproportionation agent.
METHOD OF REDUCING AROMATIC NITRO COMPOUNDS
A method for reducing a substrate selected from 2-methyl-5-nitropyridine and methyl 4-(2-fluoro-3-nitrobenzyl)piperazine-1-carboxylate is provided catalysed by a nitroreductase and a disproportionation agent.
NOVEL NON-CODING HETEROCYCLIC AMINO ACIDS (NCHAA) AND THEIR USE AS HERBICIDES
The invention relates to a novel substituted amino acids, agricultural compositions comprising the novel substituted amino acids, and their use for controlling undesired plant growth alone or in combination with crop protection agents such as pesticides or plant growth regulators.
METHOD FOR IDENTIFYING MODULATORS OF NOTCH SIGNALING
The present invention relates to use of inhibitors of Notch signalling pathway selected from the group consisting of 6-(4-Tert-Butylphenoxy)Pyridin-3-Amine (I3), its derivatives, in treating and/or preventing cancers.
METHOD FOR IDENTIFYING MODULATORS OF NOTCH SIGNALING
The present invention relates to use of inhibitors of Notch signalling pathway selected from the group consisting of 6-(4-Tert-Butylphenoxy)Pyridin-3-Amine (I3), its derivatives, in treating and/or preventing cancers.
Benzosulfonyl compounds
Provided herein are compounds and pharmaceutical compositions comprising said compounds that are useful for treating cancers. Specific cancers include those that are mediated by YAP/TAZ or those that are modulated by the interaction between YAP/TAZ and TEAD.