Compounds that inhibit HIF-2α, and compositions containing the compound(s) and methods for synthesizing the compounds, are described herein. Also described are the use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by HIF-2α.

Provided herein are small molecule activators of Nicotinamide Phosphoribosyltransferase (NAMPT), compositions comprising the compounds, and methods of using the compounds and compositions.

Provided herein are small molecule activators of Nicotinamide Phosphoribosyltransferase (NAMPT), compositions comprising the compounds, and methods of using the compounds and compositions.

A crystal form of a pyridinylphenyl compound and a preparation method therefor. Use of the crystal form in the preparation of a medicament of treating related diseases is also comprised.

A crystal form of a pyridinylphenyl compound and a preparation method therefor. Use of the crystal form in the preparation of a medicament of treating related diseases is also comprised.

Provided herein, inter alia, an electrochemiluminescence (ECL) co-reactant for an electrochemiluminescence system; an electrolyte composition (e.g., electrolyte solution) including the same; an electrochemiluminescence system for detecting a biological material using the same.

Described herein are compounds that are RAF inhibitors and their use in the treatment of disorders such as cancers.

Described herein are compounds that are RAF inhibitors and their use in the treatment of disorders such as cancers.

A compound represented by Formula (1):

##STR00001##

The compound can be used as insecticides.

A compound represented by Formula (1):

##STR00001##

The compound can be used as insecticides.