An endovascular treatment mesh device for closing outpouchings by affixing at least one amorphous hydrogel layer expandable in vivo to any or all surfaces of an expandable body comprising at least one material adapted to close said outpouching in the body. The treatment mesh further includes a telescoping center-support bar disposed therein, the center-support bar having at least two telescoping elements that act as reinforcing extension elements to minimize the risk of collapse. Hydrogel is affixed to the surface of the telescoping elements to inhibit retraction. An embodiment wherein the treatment mesh device is a stent.

A delivery device can provide sequential delivery of a plurality of intraluminal devices or tacks held in a compressed state on the delivery device. Delivery platforms on the delivery device can hold a tack in a compressed position and have a unique shape, such as a non-constant outer diameter, an hourglass shape, a tapered proximal half, ridges, dimples, etc. This unique shape can be positioned between annular pusher bands that may also be radiopaque markers. In some embodiments, the unique shape is provided by a sleeve of flexible material with the unique shape surrounding a harder inner shaft. Further, the annular pusher bands can be made of wire or sections of material to increase flexibility while remaining radiopacity. A tack deployment method can include alignment of radiopaque markers on the outer sheath and the tack to be deployed prior to deployment.

Various stents and stent-graft systems for treatment of medical conditions are disclosed. In one embodiment, an exemplary stent-graft system may be used for endovascular treatment of a thoracic aortic aneurysm. The stent-graft system may comprise proximal and distal components, each comprising a graft having proximal and distal ends, where upon deployment the proximal and distal components at least partially overlap with one another to provide a fluid passageway therebetween. The proximal component may comprise a proximal stent having a plurality of proximal and distal apices connected by a plurality of generally straight portions, where a radius of curvature of at least one of the proximal apices may be greater than the radius of curvature of at least one of the distal apices. The distal component may comprise a proximal z-stent coupled to the graft, where the proximal end of the graft comprises at least scallop formed therein that generally follows the shape of the proximal z-stent. Further, the distal component may comprise at least one z-stent stent coupled to the distal end of the graft and extending distally therefrom that reduces proximal migration of the distal component.

A tack device for holding plaque against blood vessel walls in treating atherosclerotic occlusive disease is formed as a thin, annular band of durable, flexible material having a plurality of focal elevating elements on its outer annular periphery for holding loose plaque under a spring or other expansion force against a blood vessel wall. The focal elevating elements are designed to exert a holding force on a plaque position while minimizing the amount of material surface area in contact with the plaque or blood vessel wall and reducing the potential of friction with the intraluminal surface. This approach offers clinicians the ability to perform a minimally invasive post-angioplasty treatment and produce a stent-like result without using a stent.

A stent graft assembly including a main body and a branch coupling extending radially from the main body. A proximal end of the single branch stent device is configured to seal in an ascending portion of an aorta. The assembly further includes a modular stent device including a proximal end and a distal end. The proximal end of the modular stent graft is configured to couple to a distal end of the single branch stent device. The modular stent device includes a main body configured to couple inside the main body of the single branch stent device. The modular stent device includes a bypass gate and an artery leg. The modular stent device is configured to bifurcate at a bifurcation point from the main body to the bypass gate and the artery leg outside of and distal the distal end of the single branch stent device.

An integrated valve prosthesis includes an anchor stent, a tether component, and a valve component. The anchor stent includes a self-expanding tubular frame member configured to be deployed in the annulus of an aortic valve or the aorta. The valve component includes a valve frame and a prosthetic valve coupled to the valve frame, and is configured to be deployed within the anchor stent. The tether component includes a first end coupled to the anchor stent and a second end coupled to the valve frame. In the delivery configuration, the tether component extends in a first direction from the anchor stent to the valve component, and in the deployed configuration, the tether component extends in a second direction from the anchor stent to the valve component. The second direction is generally opposite the first direction. The tether component may set the location of the valve component relative to the anchor stent.

A self-expandable occluding device can both cover the neck of an outpouching and serve as a permanent embolic plug thereby immediately stabilizing the outpouching. The self-expandable device effectively covers the neck of an outpouching with, for example, a mesh, or other at least partially occluding component, in a desired orientation across the neck of the outpouching without projecting into the parent vessel. The device incorporates elements which immediately stabilize the device in the outpouching, in effect, functioning as a permanent embolic plug. An embolic disc is combined with retention arms of flexible material, which deploy within the outpouching and provide immediate stabilization thereby retaining the occluding component or mesh across the neck of the outpouching. In illustrative embodiments, the arms are in the form of coils configured to deploy into three dimensional structures.

An intravascular treatment device is presented having an expandable frame made up of circular struts, straight struts, and bent struts forming a frame with circumference that varies over the length of the frame. Radiopaque markers can be positioned on the bent struts to indicate outer circumferences of the frame along the length of the frame. The device can be a stent or a clot retriever. If the device is a clot retriever, the proximal end of the expandable frame can be attached to a guide wire and the distal end of the expandable frame can be free to slide over the guide wire when the frame moves from a collapsed state to an expanded state and vice versa.

A vascular stent may be used to maintain or enhance patency of a blood vessel. By using multiple, separate stent elements that are balloon expandable, the multi-element stent may be stronger than a traditional self-expanding stent but may also be more flexible, due to its multiple-element configuration, than a traditional balloon-expandable stent. The stent elements are formed from a bioresorbable polymer material. The radial rigidity of the stent is configured to decrease after implantation in a vessel as the polymer is absorbed. The thickness of the stent, cell shape, polymer material, and/or treatment of the polymer material may be configured to provide a high initial radial rigidity to the vessel upon implantation and a decrease in the radial rigidity of the vessel over time.

Examples of a stent are provided with interlocking joints removably coupling adjacent axial stent segments. Mating elements forming the interlocking joints maintain engagement when the stent is in the radially compressed configuration, for example, during tracking of the stent to a treatment site of a body vessel, and become disengaged during radial expansion of the stent. When disengaged, the disconnected the axial stent segments remain discrete stent structures separated from one another along the point of treatment.