The present invention relates to a vascular prosthesis for a blood vessel of a patient, comprising: a hollow cylindrical main body having a prosthetic material, a longitudinal axis (L), and a stent frame, wherein the main body includes proximal and distal openings at proximal and distal ends, and wherein the vascular prosthesis having a first terminal stent ring attached to the prosthetic material at at least one end, and wherein the vascular prosthesis has at least one thread element attached thereto, wherein the at least one thread element reduces the diameter of the respective distal or proximal opening by tensile loading.

A spectral X-ray imaging system (100) includes an X-ray source (110) and an X-ray detector (120) that are mounted to a support structure (150). The support structure (150) is configured to rotate the X-ray source (110) and the X-ray detector (120) around two or more orthogonal axes (A-A′, B-B′). One or more processors (130) are configured to cause the system (100) to perform operations that include: generating a spectral image based on the spectral image data; and identifying, in the spectral image, a position of a first fiducial marker (180i) comprising a first material, based on a first X-ray absorption k-edge energy value (190i) of the first material.

A vascular stent, including an inner stent tube as well as a proximal support and a distal support which are arranged on an outer wall of the inner stent tube. When the vascular stent is in a compressed configuration, the proximal support and the distal support are both folded and close to the outer wall of the inner stent tube; when the vascular stent is expanded from the compressed configuration to an expanded configuration, a free end of the proximal support expands towards the distal end of the vascular stent, and a free end of the distal support expands towards the proximal end of the vascular stent. The vascular stent can be anchored to a main stent tube in a blood vessel by the proximal support and the distal support, preventing the vascular stent from shifting or becoming dislodged after being transplanted into the main stent tube.

A luminal endoprosthesis (1) at least partially delimits a prosthesis lumen (2), for implantation in an anatomical structure (3) that at least partially defines at least one cavity (4) and includes a pathological portion (13). The luminal endoprosthesis (1) includes two or more layers (5, 6, 7), at least one layer (5, 6, 7) having at least one threadlike element (8) forming an armor (9). The luminal endoprosthesis (1) includes an anchoring portion (10), for anchoring to an anatomical portion (11) of the walls of the cavity (4) of the anatomical structure (3). A working portion (12) faces the pathological portion (13) of the anatomical structure (3). The two or more layers (5, 6, 7) are separated from each other at least in the working portion (12) of the luminal endoprosthesis (1), avoiding connecting elements between one layer (5, 6, 7) and at least one adjacent layer.

A luminal endoprosthesis (1) at least partially delimits a prosthesis lumen (2), for implantation in an anatomical structure (3) that at least partially defines at least one cavity (4) and includes a pathological portion (13). The luminal endoprosthesis (1) includes two or more layers (5, 6, 7), at least one layer (5, 6, 7) having at least one threadlike element (8) forming an armor (9). The luminal endoprosthesis (1) includes an anchoring portion (10), for anchoring to an anatomical portion (11) of the walls of the cavity (4) of the anatomical structure (3). A working portion (12) faces the pathological portion (13) of the anatomical structure (3). The two or more layers (5, 6, 7) are separated from each other at least in the working portion (12) of the luminal endoprosthesis (1), avoiding connecting elements between one layer (5, 6, 7) and at least one adjacent layer.

Devices, systems and methods of endoluminally delivering a modular endoprosthetic system in accordance with various embodiments are disclosed herein for treating disease of human vasculature. In various embodiments, the modular endoprosthetic system includes a plurality of expandable endoprosthesis components that are coupled together to define the modular endoprosthetic system, wherein the modular endoprosthetic system provides for retrograde perfusion of a branch vessel from a main vessel.

Devices, systems and methods of endoluminally delivering a modular endoprosthetic system in accordance with various embodiments are disclosed herein for treating disease of human vasculature. In various embodiments, the modular endoprosthetic system includes a plurality of expandable endoprosthesis components that are coupled together to define the modular endoprosthetic system, wherein the modular endoprosthetic system provides for retrograde perfusion of a branch vessel from a main vessel.

Engageable stents disclosed herein may include an outer stent comprising an elongate body configured to be expandable between a constrained configuration and an unconstrained configuration. The elongate body in the unconstrained configuration may include a retention member and a cylindrical saddle region adjacent the retention member, the cylindrical saddle region defining a lumen extending along a longitudinal axis of the outer stent. The retention member of the outer stent may comprise a double-walled flange. The engageable stents may include an inner stent comprising an elongate body configured to be expandable between a constrained configuration and an unconstrained configuration. The elongate body in the unconstrained configuration may include a retention member and a cylindrical saddle region adjacent the retention member. The retention member of the inner stent may comprise a double-walled flange. The retention members of the outer and inner stent may be removably engageable with each other.

A stent 1 which is inserted into a catheter and extruded from the catheter into a blood vessel to dilate a blood vessel, wherein the stent is equipped with a first stent body 10 in which a plurality of first cells comprising struts arranged in a frame shape are spread in the circumferential direction and are contiguous in the central axial direction and a second stent body 20, interpolated into the first stent body, in which a plurality of second cells comprising struts arranged in a frame shape are spread in the circumferential direction and are contiguous in the central axial direction, and, in a state in which the second stent body 20 is interpolated into the first stent body 10, the intersecting portions of the second cells are arranged in the hole portions of the first cells and the first stent body 10 and the second stent body 20 are not connected to each other in the radial direction.

The techniques of this disclosure generally relate to a modular stent device that is deployed via supra aortic access through the brachiocephalic artery. The modular stent device is a base or anchor component to which additional modular stent devices can be attached to exclude diseased areas of the aorta while at the same time allowing perfusion of the left common carotid artery and the left subclavian artery.