A modular valve prosthesis includes an anchor stent and a valve component. The anchor stent includes a self-expanding tubular frame member configured to be deployed in the aorta and a proximal arm component extending from a proximal end of the tubular frame member and configured to be deployed in the sinuses of the aortic valve. The anchor stent further includes attachment members extending from an internal surface of the tubular frame member. The valve component includes a valve frame configured to be deployed within the tubular frame member of the anchor stent such that the valve frame engages with the attachment members of the tubular frame member and a prosthetic valve coupled to the valve frame.

A stent includes a high radial/crush force segment and a highly flexible segment. In an aspect, a plurality of first ring struts connected such that each of the plurality of first rings comprises a sinusoidal pattern having a plurality of apices and troughs, each first ring connected to an adjacent first ring by at least one connector. The connector extends from a ring strut of the first ring from a position near an apex of the first ring to a ring strut of the adjacent first rings near an apex of the adjacent ring, and a second stent segment comprises a plurality of second rings connected to one another to form a series of second rings.

The invention described herein relates to telescoping stents. The embodiments described herein allow for adequate securement to, accommodation for movement by, and prevention of injury of tubular organs or hollow areas of the body. Certain embodiments relate to telescoping steins with loop interlocking mechanisms. Further embodiments relate to telescoping stents with ball-in-groove interlocking mechanisms.

The invention described herein relates to telescoping stents. The embodiments described herein allow for adequate securement to, accommodation for movement by, and prevention of injury of tubular organs or hollow areas of the body. Certain embodiments relate to telescoping steins with loop interlocking mechanisms. Further embodiments relate to telescoping stents with ball-in-groove interlocking mechanisms.

A device for endovascular treatment to ameliorate aneurysm recurrences by deploying a treatment mesh having a plurality of vertically oriented elongated support reinforcement elements that are substantially parallel and oriented upon a plane in communication with the mesh. Upon deployment, the array of distal ends of the support extensions and reinforcements are substantially oriented upon a plane, which plane is in substantially the same orientation as the opening of the aneurysm into which the device was deployed. The treatment mesh may incorporate a coating of hydrogel, optionally impregnated with pharmaceutical compounds.

A device for endovascular treatment to ameliorate aneurysm recurrences by deploying a treatment mesh having a plurality of vertically oriented elongated support reinforcement elements that are substantially parallel and oriented upon a plane in communication with the mesh. Upon deployment, the array of distal ends of the support extensions and reinforcements are substantially oriented upon a plane, which plane is in substantially the same orientation as the opening of the aneurysm into which the device was deployed. The treatment mesh may incorporate a coating of hydrogel, optionally impregnated with pharmaceutical compounds.

A stent is provided that includes a body extending between a distal and a proximal end. The body is defined by a plurality of elongated members, with each elongated member extending between a distal end that is coterminous with the distal end of the body and a proximal end that is coterminous with the proximal end of the body. Each of the plurality of elongated members are arranged so as to define a lumen extending along the length of the respective plurality of elongated members, the lumen extending between the distal and proximal ends of the body so as to form a lumen length. Each of the plurality of elongated members are configured to permit drainage of a fluid from within the lumen to an environment external the stent along the entire lumen length.

A stent is provided that includes a body extending between a distal and a proximal end. The body is defined by a plurality of elongated members, with each elongated member extending between a distal end that is coterminous with the distal end of the body and a proximal end that is coterminous with the proximal end of the body. Each of the plurality of elongated members are arranged so as to define a lumen extending along the length of the respective plurality of elongated members, the lumen extending between the distal and proximal ends of the body so as to form a lumen length. Each of the plurality of elongated members are configured to permit drainage of a fluid from within the lumen to an environment external the stent along the entire lumen length.

A method and device include attaching a tether portion of a sleeve to a distal end of a catheter, placing the distal end of the catheter into a selected position within a vessel, moving a stent through a lumen of the catheter, retentively engaging a first end of the stent with a distal end of the sleeve, and detaching the sleeve about the tether portion such that the sleeve covers at least a portion of the stent at the selected position within the vessel.

A medical appliance or prosthesis may comprise one or more layers of rotational spun nanofibers, including rotational spun polymers. The rotational spun material may comprise layers including layers of polytetrafluoroethylene (PTFE). Rotational spun nanofiber mats of certain porosities may permit tissue ingrowth into or attachment to the prosthesis. Additionally, one or more cuffs may be configured to allow tissue ingrowth to anchor the prosthesis.