The disclosure relates to compounds and compositions for forming bone and methods related thereto. In one embodiment, the disclosure relates to a composition comprising a compound disclosed herein, such as 2,4-diamino-1,3,5-triazine derivatives or salts thereof, for use in bone growth processes. In a typical embodiment, a bone graft composition is implanted in a subject at a site of desired bone growth or enhancement.

The disclosure relates to compounds and compositions for forming bone and methods related thereto. In one embodiment, the disclosure relates to a composition comprising a compound disclosed herein, such as 2,4-diamino-1,3,5-triazine derivatives or salts thereof, for use in bone growth processes. In a typical embodiment, a bone graft composition is implanted in a subject at a site of desired bone growth or enhancement.

The present invention relates to diaminotriazine compounds of the formula (I) and to their use as herbicides. The present invention also relates to agrochemical compositions for crop protection and to a method for controlling unwanted vegetation. ##STR00001## wherein q is 0, 1, 2 or 3 R.sup.a is selected from the group consisting of C.sub.1-C.sub.6-haloalkoxy, C.sub.1-C.sub.6-haloalkylthio, (C.sub.1-C.sub.6-haloalkyl)sulfinyl, (C.sub.1-C.sub.6-haloalkyl)-carbonyl, etc.; R.sup.b is selected from the group consisting of halogen, OH, CN, amino, NO.sub.2, C.sub.1-C.sub.6-alkyl, C.sub.2-C.sub.6-alkenyl, C.sub.2-C.sub.6-alkynyl, C.sub.1-C.sub.6-alkoxy, etc.; R.sup.1 is selected from the group consisting of H, OH, S(O).sub.2NH.sub.2, CN, C.sub.1-C.sub.6-alkyl, C.sub.2-C.sub.6-alkenyl, C.sub.2-C.sub.6-alkynyl, (C.sub.3-C.sub.6-cycloalkyl)-C.sub.1-C.sub.4-alkyl, etc.; R.sup.2 is selected from the group consisting of H, OH, S(O).sub.2NH.sub.2, CN, C.sub.1-C.sub.6-alkyl, C.sub.2-C.sub.6-alkenyl, C.sub.2-C.sub.6-alkynyl, (C.sub.3-C.sub.6-cycloalkyl)-C.sub.1-C.sub.4-alkyl, etc.; R.sup.3 is selected from the group consisting of H, halogen, OH, CN, C.sub.1-C.sub.6-alkyl, (C.sub.1-C.sub.6-alkoxy)-C.sub.1-C.sub.6-alkyl, C.sub.3-C.sub.6-cycloalkyl, etc.; R.sup.4 is H, halogen, CN, C.sub.1-C.sub.6-alkyl, C.sub.1-C.sub.6-haloalkyl, C.sub.3-C.sub.6-cycloalkyl, C.sub.3-C.sub.6-halocycloalkyl, C.sub.1-C.sub.6-alkoxy and C.sub.1-C.sub.6-haloalkoxy; R.sup.5 is selected from the group consisting of halogen, CN, C.sub.1-C.sub.6-alkyl, C.sub.2-C.sub.6-alkenyl, C.sub.3-C.sub.6-alkynyl, C.sub.3-C.sub.6-cycloalkyl, etc.; or R.sup.4 and R.sup.5 together with the carbon atom to which they are attached form a moiety selected from the group consisting of carbonyl, C.sub.3-C.sub.6-cycloalkan-1,1-diyl, ipso-C.sub.3-C.sub.6-cycloalkendiyl, three- to six-membered saturated or partially unsaturated ipso-heterocyclodiyl; including their agriculturally acceptable salts.

The present invention relates to diaminotriazine compounds of the formula (I) and to their use as herbicides. The present invention also relates to agrochemical compositions for crop protection and to a method for controlling unwanted vegetation. ##STR00001## wherein q is 0, 1, 2 or 3 R.sup.a is selected from the group consisting of C.sub.1-C.sub.6-haloalkoxy, C.sub.1-C.sub.6-haloalkylthio, (C.sub.1-C.sub.6-haloalkyl)sulfinyl, (C.sub.1-C.sub.6-haloalkyl)-carbonyl, etc.; R.sup.b is selected from the group consisting of halogen, OH, CN, amino, NO.sub.2, C.sub.1-C.sub.6-alkyl, C.sub.2-C.sub.6-alkenyl, C.sub.2-C.sub.6-alkynyl, C.sub.1-C.sub.6-alkoxy, etc.; R.sup.1 is selected from the group consisting of H, OH, S(O).sub.2NH.sub.2, CN, C.sub.1-C.sub.6-alkyl, C.sub.2-C.sub.6-alkenyl, C.sub.2-C.sub.6-alkynyl, (C.sub.3-C.sub.6-cycloalkyl)-C.sub.1-C.sub.4-alkyl, etc.; R.sup.2 is selected from the group consisting of H, OH, S(O).sub.2NH.sub.2, CN, C.sub.1-C.sub.6-alkyl, C.sub.2-C.sub.6-alkenyl, C.sub.2-C.sub.6-alkynyl, (C.sub.3-C.sub.6-cycloalkyl)-C.sub.1-C.sub.4-alkyl, etc.; R.sup.3 is selected from the group consisting of H, halogen, OH, CN, C.sub.1-C.sub.6-alkyl, (C.sub.1-C.sub.6-alkoxy)-C.sub.1-C.sub.6-alkyl, C.sub.3-C.sub.6-cycloalkyl, etc.; R.sup.4 is H, halogen, CN, C.sub.1-C.sub.6-alkyl, C.sub.1-C.sub.6-haloalkyl, C.sub.3-C.sub.6-cycloalkyl, C.sub.3-C.sub.6-halocycloalkyl, C.sub.1-C.sub.6-alkoxy and C.sub.1-C.sub.6-haloalkoxy; R.sup.5 is selected from the group consisting of halogen, CN, C.sub.1-C.sub.6-alkyl, C.sub.2-C.sub.6-alkenyl, C.sub.3-C.sub.6-alkynyl, C.sub.3-C.sub.6-cycloalkyl, etc.; or R.sup.4 and R.sup.5 together with the carbon atom to which they are attached form a moiety selected from the group consisting of carbonyl, C.sub.3-C.sub.6-cycloalkan-1,1-diyl, ipso-C.sub.3-C.sub.6-cycloalkendiyl, three- to six-membered saturated or partially unsaturated ipso-heterocyclodiyl; including their agriculturally acceptable salts.

The disclosure relates to compounds and compositions for forming bone and methods related thereto. In one embodiment, the disclosure relates to a composition comprising a compound disclosed herein, such as 2,4-diamino-1,3,5-triazine derivatives or salts thereof, for use in bone growth processes. In a typical embodiment, a bone graft composition is implanted in a subject at a site of desired bone growth or enhancement.

The disclosure relates to compounds and compositions for forming bone and methods related thereto. In one embodiment, the disclosure relates to a composition comprising a compound disclosed herein, such as 2,4-diamino-1,3,5-triazine derivatives or salts thereof, for use in bone growth processes. In a typical embodiment, a bone graft composition is implanted in a subject at a site of desired bone growth or enhancement.

The present invention relates to diaminotriazine compounds of formula (I)

##STR00001##

wherein the variables are defined according to the description,
processes for preparing them, compositions comprising them, their use as herbicides or for the desiccation/defoliation of plants as well as a method for controlling unwanted vegetation.

The present invention relates to diaminotriazine compounds of formula (I)

##STR00001##

wherein the variables are defined according to the description,
processes for preparing them, compositions comprising them, their use as herbicides or for the desiccation/defoliation of plants as well as a method for controlling unwanted vegetation.

Disclosed are compounds inhibiting ErbBs (e.g., EGFR or Her 2), especially mutant forms of ErbBs, and BTK, pharmaceutically acceptable salts, hydrates, solvates or stereoisomers thereof and pharmaceutical compositions comprising the compounds. The compound and the pharmaceutical composition can effectively treat ErbBs (especially mutant forms of ErbBs) or BTK associated diseases, including cancer.

The present disclosure relates to biguanide derivatives of formula (I) and their rearrangement products. The present disclosure also relates to the use of these compounds in a method for treating cancer, in particular melanoma.

##STR00001##