C07D251/42

4-aryl-N-phenyl-1,3,5-triazin-2-amines containing a sulfoximine group

The present invention relates to 4-aryl-N-phenyl-1,3,5-triazin-2-amines containing a sulfoximine group of general formula (I) or (Ia) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I) or (Ia).

4-aryl-N-phenyl-1,3,5-triazin-2-amines containing a sulfoximine group

The present invention relates to 4-aryl-N-phenyl-1,3,5-triazin-2-amines containing a sulfoximine group of general formula (I) or (Ia) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I) or (Ia).

ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICES
20180069183 · 2018-03-08 ·

The present disclosure relates to organic electroluminescent materials and organic electroluminescent devices, in particular, discloses a compound of formula (1), wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are each independently selected from hydrogen, a substituted or unsubstituted C.sub.1-20 alkyl, a substituted or unsubstituted C.sub.3-20 cycloalkyl, a substituted or unsubstituted aromatic hydrocarbyl, or a substituted or unsubstituted aromatic heterocyclic group; and at least one of R.sub.1, R.sub.2, R.sub.3 and R.sub.4 contains a group having a hole-transporting ability; and at least one of R.sub.1, R.sub.2, R.sub.3 and R.sub.4 contains a group having an electron-transporting ability; A and B each independently represent hydrogen, a substituted or unsubstituted, fused aromatic ring, or a substituted or unsubstituted, fused heteroaromatic ring containing a heteroatom(s) selected from O, N and S.

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ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICES
20180069183 · 2018-03-08 ·

The present disclosure relates to organic electroluminescent materials and organic electroluminescent devices, in particular, discloses a compound of formula (1), wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are each independently selected from hydrogen, a substituted or unsubstituted C.sub.1-20 alkyl, a substituted or unsubstituted C.sub.3-20 cycloalkyl, a substituted or unsubstituted aromatic hydrocarbyl, or a substituted or unsubstituted aromatic heterocyclic group; and at least one of R.sub.1, R.sub.2, R.sub.3 and R.sub.4 contains a group having a hole-transporting ability; and at least one of R.sub.1, R.sub.2, R.sub.3 and R.sub.4 contains a group having an electron-transporting ability; A and B each independently represent hydrogen, a substituted or unsubstituted, fused aromatic ring, or a substituted or unsubstituted, fused heteroaromatic ring containing a heteroatom(s) selected from O, N and S.

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HETEROARYL INHIBITORS OF PDE4

The present invention relates to compounds and methods useful as inhibitors of phosphodiesterase 4 (PDE4) for the treatment or prevention of inflammatory diseases and other diseases involving elevated levels of cytokines and proinflammatory mediators.

HETEROARYL INHIBITORS OF PDE4

The present invention relates to compounds and methods useful as inhibitors of phosphodiesterase 4 (PDE4) for the treatment or prevention of inflammatory diseases and other diseases involving elevated levels of cytokines and proinflammatory mediators.

4-ARYL-N-PHENYL-1,3,5-TRIAZIN-2-AMINES CONTAINING A SULFOXIMINE GROUP

The present invention relates to 4-aryl-N-phenyl-1,3,5-triazin-2-amines containing a sulfoximine group of general formula (I) or (Ia) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I) or (Ia).

Triazine compounds and compositions thereof and methods for treating malaria and chemoprophylaxis

Disclosed herein are triazine compounds and methods of making and using thereof to treat malaria, provide chemoprophylaxis, and/or treat or inhibit infection by one or more Plasmodium spp.

Triazine compounds and compositions thereof and methods for treating malaria and chemoprophylaxis

Disclosed herein are triazine compounds and methods of making and using thereof to treat malaria, provide chemoprophylaxis, and/or treat or inhibit infection by one or more Plasmodium spp.

4-aryl-N-phenyl-1,3,5-triazin-2-amines containing a sulfoximine group

The present invention relates to 4-aryl-N-phenyl-1,3,5-triazin-2-amines containing a sulfoximine group of general formula (I) or (Ia) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I) or (Ia). ##STR00001##