A prosthesis delivery comprising a rotatable inner cannula and a prosthesis releasably coupled to a proximal end of the inner cannula is disclosed. The inner cannula has a first position in which the prosthesis is retained on the cannula and a second position in which the prosthesis is released. At least one magnet is disposed on the inner cannula. A handle assembly is disposed about a distal portion of the inner cannula, the handle assembly comprising a rotary collar having at least one magnet disposed on the inner surface thereof, wherein the at least one magnet disposed on the rotatable inner cannula and the at least one magnet disposed on the inner surface of the rotary collar comprise a magnetic attraction. The magnetic attraction translates torque from rotation of the rotary collar to rotate the inner cannula from the first position to the second position to thereby release the prosthesis.

A vascular stent assembly includes at least a first and a second strut, each including a thickness and a depth. The assembly includes a pair of end radii, with each of the first and second struts extending from one of the pair of end radii. A thickness of at least one of the first and second struts includes a tapering profile extending from one of the end radii to another of the end radii, the tapering profile following a continuously increasing or decreasing function through at least half a length of the at least one strut.

An implantable biliary or pancreatic stent for implanting in the gastrointestinal tract having a first end for placing in the bile duct or the pancreatic duct and a second end for placing in the duodenum, the first end including a pressure sensor arranged to measure bile duct or pancreatic duct pressure, respectively, and the second end including a pressure sensor arranged to measure duodenal pressure. Each pressure sensor can include an electronic circuit with electronic components and a substrate for receiving the electronic circuit and electronic components, wherein said substrate is a flexible membrane. The flexible membrane can be a sleeve surrounding the stent, or the flexible membrane can be a flexible tube that is part of a thin tube that forms the stent, in particular the flexible membrane can have a thickness of 80-150 μm. A manufacturing method is disclosed for providing said implantable biliary or pancreatic stent.

An implantable biliary or pancreatic stent for implanting in the gastrointestinal tract having a first end for placing in the bile duct or the pancreatic duct and a second end for placing in the duodenum, the first end including a pressure sensor arranged to measure bile duct or pancreatic duct pressure, respectively, and the second end including a pressure sensor arranged to measure duodenal pressure. Each pressure sensor can include an electronic circuit with electronic components and a substrate for receiving the electronic circuit and electronic components, wherein said substrate is a flexible membrane. The flexible membrane can be a sleeve surrounding the stent, or the flexible membrane can be a flexible tube that is part of a thin tube that forms the stent, in particular the flexible membrane can have a thickness of 80-150 μm. A manufacturing method is disclosed for providing said implantable biliary or pancreatic stent.

A device and method for repair of a patient's aorta is disclosed. The device includes a first component including an outer diameter equal to a first diameter, a second component attached to a distal end of the first component, and a plurality of third components positioned in a chamber defined in the second component. The second component includes a proximal surface extending outwardly from the distal end of the first component, and a plurality of openings defined in the proximal surface. Each third component includes a passageway extending inwardly from an opening of the plurality of openings defined in the proximal surface. Each passageway is sized to receive a tubular conduit, and the proximal surface has an outer edge that defines a second diameter greater than the first diameter.

A prosthetic heart includes a support structure, an actuator member, a plurality of leaflets, and a sealing material. The support structure includes a plurality of struts movably coupled together such that the support structure moves incrementally between a radially compressed state and a radially expanded state. The struts include a plurality of commissure struts. The actuator member is coupled to the struts of the support structure and is configured to incrementally move the support structure between the radially compressed state and the radially expanded state and to automatically lock the support structure in a particular state. The leaflets are coupled to the commissure struts of the support structure and configured to allow unidirectional blood flow through the prosthetic heart valve. The sealing material is coupled to the support structure and includes a plurality of commissure extensions that wrap around and are coupled to the commissure struts of the support structure.

A prosthetic heart includes a support structure, an actuator member, a plurality of leaflets, and a sealing material. The support structure includes a plurality of struts movably coupled together such that the support structure moves incrementally between a radially compressed state and a radially expanded state. The struts include a plurality of commissure struts. The actuator member is coupled to the struts of the support structure and is configured to incrementally move the support structure between the radially compressed state and the radially expanded state and to automatically lock the support structure in a particular state. The leaflets are coupled to the commissure struts of the support structure and configured to allow unidirectional blood flow through the prosthetic heart valve. The sealing material is coupled to the support structure and includes a plurality of commissure extensions that wrap around and are coupled to the commissure struts of the support structure.

A heart valve assembly includes an inner frame comprising a graft covering housing a prosthetic heart valve, wherein the graft covering extends around the prosthetic heart valve for providing sealing to the heart valve, an outer frame formed from a metallic material and defining a gridded configuration, and being secured to the graft covering by a plurality of stitches, and a sealing material positioned externally to the outer frame for providing sealing between the outer frame and a patient's anatomical wall to prevent paravalvular leaks. The sealing material includes a plurality of radially extending fibers that extend outwardly of the outer frame. The graft covering is made of polyester, polytetrafluoroethylene, expanded polytetrafluoroethylene, or a polymer.

A delivery system for delivering and deploying stents with proximal and distal apices includes a guidewire catheter, a nose cone assembly, a proximal capture portion and a stent graft with proximal and distal stents. The nose cone assembly is at the distal end of the guidewire catheter and includes a nose cone and a distal capture portion. The proximal capture portion is proximal to the distal capture portion of the nose cone assembly. The proximal stent is releasably secured to the distal capture portion and the distal stent is releasably secured to the proximal capture portion. The stent graft can be deployed by releasing the proximal stent and the distal stent from proximal and distal capture portions of the delivery system.

A delivery system for delivering and deploying stents with proximal and distal apices includes a guidewire catheter, a nose cone assembly, a proximal capture portion and a stent graft with proximal and distal stents. The nose cone assembly is at the distal end of the guidewire catheter and includes a nose cone and a distal capture portion. The proximal capture portion is proximal to the distal capture portion of the nose cone assembly. The proximal stent is releasably secured to the distal capture portion and the distal stent is releasably secured to the proximal capture portion. The stent graft can be deployed by releasing the proximal stent and the distal stent from proximal and distal capture portions of the delivery system.