A method for expanding a constricted location of a urethra of a subject, the method including inserting a urethral implant, and an implant sheath that covers the urethral implant, through the urethra for implanting the urethral implant in the constricted location, the urethral implant being in a compressed configuration within the implant sheath, releasing the urethral implant from the implant sheath until the urethral implant exits from the implant sheath, thereby expanding the urethral implant from the compressed configuration to an expanded configuration, applying, by the urethral implant, continuous pressure on tissues of the urethra at the constricted location, and retracting the implant sheath from the urethra.

A method for expanding a constricted location of a urethra of a subject, the method including inserting a urethral implant, and an implant sheath that covers the urethral implant, through the urethra for implanting the urethral implant in the constricted location, the urethral implant being in a compressed configuration within the implant sheath, releasing the urethral implant from the implant sheath until the urethral implant exits from the implant sheath, thereby expanding the urethral implant from the compressed configuration to an expanded configuration, applying, by the urethral implant, continuous pressure on tissues of the urethra at the constricted location, and retracting the implant sheath from the urethra.

A stent-deployment assembly for use with a guidewire comprises a biliary stent and an elongated stent-conveyance tube comprising a guidewire-retaining segment that includes respective distal and proximal apertures defining a guidewire-path therethrough, and a lengthways laterally-breachable portion. In a stent-advancement configuration, the guidewire passes through the respective apertures so as to interiorly traverse the guidewire-retaining segment, and the stent is arranged to surround a stent-conveyance tube segment that is proximally displaced from the guidewire-retaining segment, for advancement of the stent together with the stent-conveyance tube along the guidewire into a body lumen of a human subject. When the stent is disposed, in the stent-advancement configuration, at a target deployment location within the lumen, a proximal-direction withdrawal of the stent-conveyance tube is effective to cause the guidewire to breach the laterally-breachable portion of the guidewire-retaining segment so as to decouple the guidewire from the tube without longitudinal displacement of the guidewire.

A method and device to correctly orient an intracranial occlusion device, such as a stent having differential porosity, with respect to desired areas of greater or lesser blood flow (e.g., branch vessels and aneurysms, respectively), said device being particularly adapted for use in treating aneurysms in intracranial or other tortuous vasculature. An intravascular device comprising a delivery catheter having a hub and angular lumen capable of constraining a pusher wire within a packaging catheter to deploy said stent in an orientation wherein the area of least porosity abuts the aneurysm, and area of maximal porosity permits blood flow to a branch or other vessel. A method of using same.

An expandable stent to enhance the supply of blood to downstream tissue which is being supplied with blood through a diseased intracranial artery with a stenosis formed therein by plaque with a bore therethrough. The expandable stent includes first and second end portions and a central portion. The central portion is configured in the expanded state of the stent to contact the stenosis with the first and second end portions anchoring the stent in the artery.

An expandable stent to enhance the supply of blood to downstream tissue which is being supplied with blood through a diseased intracranial artery with a stenosis formed therein by plaque with a bore therethrough. The expandable stent includes first and second end portions and a central portion. The central portion is configured in the expanded state of the stent to contact the stenosis with the first and second end portions anchoring the stent in the artery.

A method and device to correctly orient an intracranial occlusion device, such as a stent having differential porosity, with respect to desired areas of greater or lesser blood flow (e.g., branch vessels and aneurysms, respectively), said device being particularly adapted for use in treating aneurysms in intracranial or other tortuous vasculature. An intravascular device comprising a delivery catheter having a hub and angular lumen capable of constraining a pusher wire within a packaging catheter to deploy said stent in an orientation wherein the area of least porosity abuts the aneurysm, and area of maximal porosity permits blood flow to a branch or other vessel. A method of using same.

The present disclosure provides an endoprosthesis where a preferably polymeric coating has a number of surface features such as protrusions or textures that are arranged in a micropattern. The endoprosthesis optionally has an expanded state and a contracted state, and in some cases includes a stent with a polymeric coating attached to an outer surface of the stent. The stent may have an inner surface defining a lumen, an outer surface, and a stent thickness defined between the inner surface and outer surface. The stent may comprise a plurality of surface textures extending from the stent surfaces, wherein the textures are arranged in a macropattern.

An expandable stent (1) to enhance the supply of blood to downstream tissue which is being supplied with blood through a diseased intracranial artery (100) with a stenosis (102) formed therein by plaque with a bore (103) therethrough. The expandable stent (1) comprises first and second end portions (3,4) joined by a central portion (5). The central portion (5) is configured in the expanded state of the stent (1) to be located in the bore (103) of the stenosis (102) with the first and second end portions (3,4) abutting non-diseased parts (104,106) of the artery (100) adjacent the proximal and distal ends (105,107) of the stenosis (102) for anchoring the stent (1) in the artery (100). The central portion (5) with the stent (1) in the expanded state is configured to apply a radial outward pressure to the stenosis (102) such that the diameter of the bore (103) of the stenosis (102) is maintained at its current diameter or increased to approximately 50% of the non-diseased parts (104,106) of the artery (100).

An expandable stent (1) to enhance the supply of blood to downstream tissue which is being supplied with blood through a diseased intracranial artery (100) with a stenosis (102) formed therein by plaque with a bore (103) therethrough. The expandable stent (1) comprises first and second end portions (3,4) joined by a central portion (5). The central portion (5) is configured in the expanded state of the stent (1) to be located in the bore (103) of the stenosis (102) with the first and second end portions (3,4) abutting non-diseased parts (104,106) of the artery (100) adjacent the proximal and distal ends (105,107) of the stenosis (102) for anchoring the stent (1) in the artery (100). The central portion (5) with the stent (1) in the expanded state is configured to apply a radial outward pressure to the stenosis (102) such that the diameter of the bore (103) of the stenosis (102) is maintained at its current diameter or increased to approximately 50% of the non-diseased parts (104,106) of the artery (100).