C07D285/125

THIOETHER COMPOUNDS AS NITRIFICATION INHIBITORS

Provided herein are a use of thioether compounds of formula I as nitrification inhibitors, and agricultural mixtures and compositions including the thioether compounds.

THIOETHER COMPOUNDS AS NITRIFICATION INHIBITORS

Provided herein are a use of thioether compounds of formula I as nitrification inhibitors, and agricultural mixtures and compositions including the thioether compounds.

N-hydroxylsulfonamide derivatives as new physiologically useful nitroxyl donors

The invention relates to N-hydroxysulfonamide derivatives that donate nitroxyl (HNO) under physiological conditions and are useful in treating and/or preventing the onset and/or development of diseases or conditions that are responsive to nitroxyl therapy, including heart failure and ischemia/reperfusion injury. Novel N-hydroxysulfonamide derivatives release NHO at a controlled rate under physiological conditions, and the rate of HNO release is modulated by varying the nature and location of functional groups on the N-hydroxysulfonamide derivatives.

N-hydroxylsulfonamide derivatives as new physiologically useful nitroxyl donors

The invention relates to N-hydroxysulfonamide derivatives that donate nitroxyl (HNO) under physiological conditions and are useful in treating and/or preventing the onset and/or development of diseases or conditions that are responsive to nitroxyl therapy, including heart failure and ischemia/reperfusion injury. Novel N-hydroxysulfonamide derivatives release NHO at a controlled rate under physiological conditions, and the rate of HNO release is modulated by varying the nature and location of functional groups on the N-hydroxysulfonamide derivatives.

Heterocyclic inhibitors of glutaminase

The invention relates to novel heterocyclic compounds and pharmaceutical preparations thereof. The invention further relates to methods of treatment using the novel heterocyclic compounds of the invention.

Heterocyclic inhibitors of glutaminase

The invention relates to novel heterocyclic compounds and pharmaceutical preparations thereof. The invention further relates to methods of treatment using the novel heterocyclic compounds of the invention.

Haloalkyl heteroaryl benzamide compounds

A new class of haloalkyl heteroaryl benzamides is described. These compounds show strong activity against hepatitis viruses.

Vinylogous thioester compounds and methods of use

Provided herein are vinylogous thioester compounds and methods for using the compounds.

Vinylogous thioester compounds and methods of use

Provided herein are vinylogous thioester compounds and methods for using the compounds.

Compositions and coatings with non-chrome corrosion inhibitor particles

Compositions are described for protecting a metal surface against corrosion. The composition includes a corrosion-inhibiting particle. The corrosion inhibiting particle may be usable in an epoxy resin-based coating or an olefin resin-based coating. The particle may include a core and a protectant. The core may include a water soluble corrosion inhibitor. The protectant may be disposed on at least a portion of a surface of the core and may be covalently or ionically bonded to a thiol group of the corrosion inhibitor. The protectant may be configured to reduce reaction between the core and the epoxy resin or the olefin resin. Methods of making the compositions are also disclosed.