A lipid derivative in which a hydrophilic polymer is bound through a cyclic benzylidene acetal linker, and which can accurately control a hydrolysis rate in the weakly acidic environment of a living body to detach the hydrophilic polymer from a lipid membrane structure. The lipid derivative is represented by formula (1):

##STR00001##

wherein, R.sup.1 and R.sup.6 are each independently a hydrogen atom or a hydrocarbon group; R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are each independently an electron-withdrawing or electron-donating substituent or a hydrogen atom; R.sup.7 is a hydrocarbon group having from 8 to 24 carbon atoms, an acyl group having from 8 to 24 carbon atoms, a cholesterol derivative, a glycerolipid, a phospholipid or a sphingolipid; P is a hydrophilic polymer; s is 1 or 2, t is 0 or 1, and s+t is 1 or 2; and Z.sup.1 and Z.sup.2 are each independently a selected divalent spacer.

A lipid derivative in which a hydrophilic polymer is bound through a cyclic benzylidene acetal linker, and which can accurately control a hydrolysis rate in the weakly acidic environment of a living body to detach the hydrophilic polymer from a lipid membrane structure. The lipid derivative is represented by formula (1):

##STR00001##

wherein, R.sup.1 and R.sup.6 are each independently a hydrogen atom or a hydrocarbon group; R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are each independently an electron-withdrawing or electron-donating substituent or a hydrogen atom; R.sup.7 is a hydrocarbon group having from 8 to 24 carbon atoms, an acyl group having from 8 to 24 carbon atoms, a cholesterol derivative, a glycerolipid, a phospholipid or a sphingolipid; P is a hydrophilic polymer; s is 1 or 2, t is 0 or 1, and s+t is 1 or 2; and Z.sup.1 and Z.sup.2 are each independently a selected divalent spacer.

A composition effective for removing solder fluxes either as a concentrated material or when diluted with water. The composition is effective in removing all types of solder fluxes including rosin type, resin type, no-clean, low residue, lead-free, organic acid and water soluble soldering fluxes. The composition comprises isopropylidene glycerol and an alkali and has a pH of greater than 7.5. The composition may contain additional optional solvents and additives to enhance cleaning of articles or to impart other properties to the composition. The composition can be contacted with a surface to be cleaned in a number of ways and under a number of conditions depending on the manufacturing or processing variables present.

Provided is lipid and methods of making such lipid having the structure of Formula A:

##STR00001## each R is an alkyl having a carbon backbone of C.sub.12 to C.sub.16 having 1 to 3 C?C double bonds, at least one having Z-geometry; R is an optional alkyl of C.sub.2 to C.sub.24 having 0 to 3 C?C double bonds; each R, and the R alkyl group if present, is optionally substituted at one or more positions with a C.sub.1 to C.sub.3 alkyl; W and X are O or S; Y is absent and C.sup.1 and C.sup.2 are bonded, or Y is present and is a metheno, etheno or ethyno bridge optionally substituted with an alkylamino chain [(CH.sub.2).sub.mNG.sup.1G.sup.2G.sup.3], wherein m is 1-5 and G.sup.1, G.sup.2 are, independently, C.sub.1 to C.sub.3 alkyl, G.sup.3 is absent, hydrogen or C.sub.1 to C.sub.3 alkyl, or wherein NG.sup.1G.sup.2G.sup.3 is a heterocycle; and Z and Z are H or alkylamino.

Provided is lipid and methods of making such lipid having the structure of Formula A:

##STR00001## each R is an alkyl having a carbon backbone of C.sub.12 to C.sub.16 having 1 to 3 C?C double bonds, at least one having Z-geometry; R is an optional alkyl of C.sub.2 to C.sub.24 having 0 to 3 C?C double bonds; each R, and the R alkyl group if present, is optionally substituted at one or more positions with a C.sub.1 to C.sub.3 alkyl; W and X are O or S; Y is absent and C.sup.1 and C.sup.2 are bonded, or Y is present and is a metheno, etheno or ethyno bridge optionally substituted with an alkylamino chain [(CH.sub.2).sub.mNG.sup.1G.sup.2G.sup.3], wherein m is 1-5 and G.sup.1, G.sup.2 are, independently, C.sub.1 to C.sub.3 alkyl, G.sup.3 is absent, hydrogen or C.sub.1 to C.sub.3 alkyl, or wherein NG.sup.1G.sup.2G.sup.3 is a heterocycle; and Z and Z are H or alkylamino.

There is provided a compound which is (a) a pyrimidine sulfonamide of formula (I) or (b) a pharmaceutically acceptable salt thereof, crystalline forms of the compound, processes for obtaining the compound, pharmaceutical intermediates used in the manufacture of the compound, and pharmaceutical compositions containing the compound. ##STR00001## The compound is useful in the treatment of a disease/condition in which modulation of chemokine receptor activity is beneficial.

There is provided a compound which is (a) a pyrimidine sulfonamide of formula (I) or (b) a pharmaceutically acceptable salt thereof, crystalline forms of the compound, processes for obtaining the compound, pharmaceutical intermediates used in the manufacture of the compound, and pharmaceutical compositions containing the compound. ##STR00001## The compound is useful in the treatment of a disease/condition in which modulation of chemokine receptor activity is beneficial.

A process for synthesising a defined compound, such as solketal, wherein the process comprises subjecting a solution comprising another defined compound, such as glycerol, to a potential difference. A compound and a composition obtainable by the process, and a product comprising the compound or the composition.

A process for synthesising a defined compound, such as solketal, wherein the process comprises subjecting a solution comprising another defined compound, such as glycerol, to a potential difference. A compound and a composition obtainable by the process, and a product comprising the compound or the composition.

The present invention relates to the field of perfumery. More particularly, it concerns valuable new chemical intermediates for producing perfuming ingredients. Moreover, the present invention comprises also a process for producing compound of formula (I).