Provided is an organic light emitting device including a light emitting layer comprising a compound of Chemical Formula 1 and a first organic material layer comprising a compound of Chemical Formula 2:

##STR00001## wherein: Cy1 to Cy5 are each independently one selected from among a substituted or unsubstituted: aromatic hydrocarbon ring, aliphatic hydrocarbon ring, and aromatic hetero ring, or a ring in which two or more rings selected from the above group are fused, one or more of Cy1 to Cy5 are a ring of Chemical Formula 1-A:

##STR00002## one to three of a* to d* are a position fused to or linked to Chemical Formula 1;

##STR00003## L1 to L3 are each independently a direct bond or a substituted or unsubstituted: arylene or divalent heterocyclic group; and Ar1 and Ar2 are each independently a substituted or unsubstituted: aryl or heterocyclic group.

The present disclosure provides, for example, a compound represented by general formula (6) below or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate of the compound or salt:

##STR00001##

wherein X.sub.1, X.sub.2, X.sub.3 and X.sub.4 are each independently —CR.sub.2═ or —N═, R.sub.2 is, for example, a halogen atom, R.sub.1 is, for example, —S(═O).sub.2—NH—R.sub.8, R.sub.8 is, for example, a C1-6 alkyl group, R.sub.3 is, for example, a hydrogen atom, R.sub.5 is, for example, a halogen atom, R.sub.6 is, for example, a hydrogen atom, and R.sub.4 is, for example, a cyclopropyl group. The compounds, salts or solvates provided by the present disclosure exhibit high RAF/MEK complex-stabilizing activity and can be used for the treatment or prevention of cell proliferative disorders, particularly cancers.

A compound of formula (1)

##STR00001##

wherein X.sub.1 is CR.sub.1 or a nitrogen atom, X.sub.2 is CR.sub.2 or a nitrogen atom, X.sub.3 is CR.sub.3 or a nitrogen atom, X.sub.4 is CR.sub.4 or a nitrogen atom, X.sub.5 is CR.sub.5 or a nitrogen atom, X.sub.6 is CR.sub.6 or a nitrogen atom, X.sub.7 is CR.sub.7, a nitrogen atom, or a carbon atom single-bonded to X.sub.8, X.sub.8 is CR.sub.8, a nitrogen atom, or a carbon atom single-bonded to X.sub.7, X.sub.9 is CR.sub.9 or a nitrogen atom, X.sub.10 is CR.sub.10 or a nitrogen atom, X.sub.11 is CR.sub.11 or a nitrogen atom, X.sub.12 is CR.sub.12 or a nitrogen atom, and Q is CR.sub.Q or a nitrogen atom, and Y is NR.sub.Y1, an oxygen atom, a sulfur atom, C(R.sub.Y2)(R.sub.Y3) or Si(R.sub.Y4)(R.sub.Y5), each R being a hydrogen atom or a substituent.

Electrolytes and electrolyte additives for energy storage devices comprising functional thiophene compounds are disclosed. The energy storage device comprises a first electrode and a second electrode, wherein at least one of the first electrode and the second electrode is a Si-based electrode, a separator between the first electrode and the second electrode, an electrolyte, and at least one electrolyte additive selected from a thiophene compound.

The invention relates to intermediates useful in the preparation of halichondrin compounds, methods for preparing the same and use thereof, such as halichondrins, eribulin, or their analogs. The intermediates, the methods and use thereof are used for the synthesis of the C20-C26 fragment of halichondrin compounds. The raw materials in the synthetic route of the invention are cheap and easily obtained, the sources and the qualities of the raw materials are reliable. The choice of the methods useful in the synthesis of chiral central structures are based on the structural characteristics of the reactants, thus effectively improving the synthesis efficiency, reducing the difficulties and risks of product quality control, and avoiding the use of highly toxic and expensive organotin catalysts to significantly decrease costs and improve environmental friendliness.

A compound having Nrf2-activating action is provided. The compound is represented by formula (I), a salt of the compound, or a solvate of the compound or salt:

##STR00001##

wherein R.sup.1a and R.sup.1b are identical or different and represent a hydrogen atom, an alkyl group, or a halogen atom; R.sup.2 represents an optionally substituted group derived from a heterocycle, and the heterocycle represents thiophene, furan, pyrrole, thiazole, or a fused ring including any of these heterocycles; R.sup.4 and R.sup.5 are identical or different and represent a hydrogen atom or an optionally substituted alkyl group, or R.sup.4 and R.sup.5 bind with each other to form —NH—CH—N—; R.sup.6 represents an optionally substituted alkyl group; A.sup.1, A.sup.2, A.sup.3, and A.sup.4 are identical or different and represent CH or N wherein the number of N is 1 or less; and Z represents a hydrogen atom or a halogen atom.

Provided organic light emitting device (OLED) comprising compounds having Formula I:

##STR00001##

wherein rings A, B, C, D, E, and F are each independently a single or fused ring system, consisting of one or more 5-membered or 6-membered carbocyclic or heterocyclic rings; L.sup.1, L.sup.2, L.sup.3, L.sup.4, L.sup.5, and L.sup.6 are each independently optionally present or is selected from the group consisting of O, S, Se, BR, BRR′, NR, C═R, CRR′, SiRR′, P(O)R, and GeRR′; a, b, c, d, e and f are each 0 for not present or 1 for present; each of R, R′, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, and R.sup.6 is independently a hydrogen or a substituent; and any two of adjacent R, R′, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, and R.sup.6 can be joined or fused to form a ring. The compound is an ETL.

The present invention is directed to compounds having the Formulae (Ia), (Ib), (Ic), or (Id); or the Formulae (II), (IIa), (IIb), or (IIc); or the Formulae (III), (IIIa), (IIIb), (IIIc), (IIId), or (IIIe), and pharmaceutically acceptable salts, solvates, clathrates and prodrugs of any Formula thereof, compositions thereof, and methods for the treatment of a condition associated with a dysfunction in proteostasis.

A light emitting element that includes a first electrode, a second electrode facing the first electrode, and an emission layer between the first electrode and the second electrode is provided. The emission layer includes a polycyclic compound represented by Formula 1. The light emitting element has a reduced driving voltage and an increased efficiency.

##STR00001##

This invention discloses oligosilane compounds. These compounds can be used in OLEDs.