The invention relates to a method for carrying out organic reactions with fine-particulate alkali metal dispersions in a continuous operation, preferably on a rotary disc reactor. This method can be used primarily in the production of coupling products following Wurtz synthesis, and in the production of macrocycles using acyloin condensation.

The invention relates to a method for producing hydridosilanes, in which siloxanes containing SiH groups are reacted in the presence of a cationic Si(II) compound as a catalyst.

The mechanochemically functionalizing silicon nanoparticles and the functionalized silicon nanoparticles are described. The processes include applying shear forces to silicon metal the presence of an alkane and thereby functionalizing the silicon with an alkyl-functionalization. The resulting product includes a plurality of silicon nanoparticles each carrying an alkyl-functionalization derived from an alkane.

The mechanochemically functionalizing silicon nanoparticles and the functionalized silicon nanoparticles are described. The processes include applying shear forces to silicon metal the presence of an alkane and thereby functionalizing the silicon with an alkyl-functionalization. The resulting product includes a plurality of silicon nanoparticles each carrying an alkyl-functionalization derived from an alkane.

A reversible photo-switchable isomerization of novel sterically hindered 2,2,6,6-tetramethyl-4,4-bis((trimethylsilyl)ethynyl)azobenzene and its synthesis.

The present disclosure describes novel silylated heteroaromatic derivatives, including those prepared by methods comprising the use of hydrosilanes and at least one strong base, the definition of strong base now also including hydroxide, especially KOH.

The invention relates to a method for carrying out organic reactions with fine-particulate alkali metal dispersions in a continuous operation, preferably on a rotary disc reactor. This method can be used primarily in the production of coupling products following Wurtz synthesis, and in the production of macrocycles using acyloin condensation.

The present invention is related to silicon nanoparticles, a pharmaceutical composition comprising silicon nanoparticles, a method for synthesis of the silicon nanoparticles and their use for in vivo diagnostics, visualization of drug delivery or staining of cells, biological processes or pathways. The silicon nanoparticles are characterized that they comprise a silicon core of a size of 1 to 10 nm and are terminated with allylamine or poly(allylamine) comprising up to 10 allylamine groups.

The present invention describes chemical systems and methods for silylating NH bonds of aliphatic amines, said system or method comprising or consisting essentially of a mixture of (a) at least one organosilane and (b) at least one hydroxide, especially KOH, said system being preferably, but not necessarily substantially free of a transition-metal compound, and said methods comprising contacting a quantity of the organic substrate with a mixture of (a) at least one organosilane and (b) at least one strong base, under conditions sufficient to replace an NH bond with a silyl NSi bond.

The present invention is directed to a mild, efficient, and general direct C(sp)-H bond silylation. Various embodiments includes methods, each method comprising or consisting essentially of contacting at least one organic substrate comprising a terminal alkynyl CH bond, with a mixture of at least one organosilane and an alkali metal hydroxide, alkali metal alkoxide, or alkali metal hydride under conditions sufficient to form a silylated terminal alkynyl moiety. The methods are operable in the presence or substantially absence of transition-metal compounds. The systems associated with these methods are also disclosed.