An oil-soluble phosphorus antiwear additive and a lubricating composition including the ashless antiwear additive having improved copper corrosion performance obtained by reacting an organic hydroxy compound with phosphorus pentasulfide to form a reaction product, distilling the reaction product and recovering a condensate, and reacting the condensate with an unsaturated ester of a carboxylic acid to form an oil-soluble phosphorus antiwear additive.

The present invention relates to a preparation method for pyrimidine-2-amine and, more specifically, to a method for preparing a pyrimidine-2-amine compound via a pyrimidine-2-iminium salt intermediate by using a nucleophilic imine-type reagent, in which various amino functional groups are selectively introduced at position No. 2 of pyrimidine.

The invention relates to thiophosphates and derivatives thereof useful as antiwear additive components, lubricant additive compositions and lubricant compositions each comprising such compounds, methods for making and using the same, including methods of lubricating machines and machine parts and methods of extending the useful life of elastomeric seal components of such machines.

The invention relates to thiophosphates and derivatives thereof useful as antiwear additive components, lubricant additive compositions and lubricant compositions each comprising such compounds, methods for making and using the same, including methods of lubricating machines and machine parts and methods of extending the useful life of elastomeric seal components of such machines.

The present invention relates to a process for preparation of Echothiophate Iodide (I). Echothiophate Iodide (I) obtained by the process of the present invention is obtained as new crystalline form designated as Form-SET. ##STR00001## The process for preparation of Echothiophate Iodide (I) according to present invention is an ecofriendly process that avoids the use of hazardous solvent systems and provides Echothiophate Iodide (I) of high purity. Pharmaceutical composition of the said crystalline Form-SET of Echothiophate Iodide (I) of high purity is useful in the treatment of ocular disorders like Glaucoma.

The present invention relates to a process for preparation of Echothiophate Iodide (I). Echothiophate Iodide (I) obtained by the process of the present invention is obtained as new crystalline form designated as Form-SET. ##STR00001## The process for preparation of Echothiophate Iodide (I) according to present invention is an ecofriendly process that avoids the use of hazardous solvent systems and provides Echothiophate Iodide (I) of high purity. Pharmaceutical composition of the said crystalline Form-SET of Echothiophate Iodide (I) of high purity is useful in the treatment of ocular disorders like Glaucoma.

The invention relates to thiophosphates and derivatives thereof useful as antiwear additive components, lubricant additive compositions and lubricant compositions each comprising such compounds, methods for making and using the same, including methods of lubricating machines and machine parts and methods of extending the useful life of elastomeric seal components of such machines.

The present invention relates to a process for preparation of Echothiophate Iodide (I). Echothiophate Iodide (I) obtained by the process of the present invention is obtained as new crystalline form designated as Form-SET.

##STR00001##

The process for preparation of Echothiophate Iodide (I) according to present invention is an ecofriendly process that avoids the use of hazardous solvent systems and provides Echothiophate Iodide (I) of high purity. Pharmaceutical composition of the said crystalline Form-SET of Echothiophate Iodide (I) of high purity is useful in the treatment of ocular disorders like Glaucoma.

The present disclosure relates to the discovery of certain ashless antiwear additives in the form of dialkyl dithiophosphate triester compounds having specific oxygen ester moieties and a specific sulfur ester moiety that combine to provide an antiwear additive that achieves performance in lubricants without the need for (or with reduced levels of) metals provided by more traditional metal-based antiwear additives. Thus, the ashless antiwear additives of the present disclosure can supplement and/or replace traditional ZDDP additives used in lubricants and still achieve desired wear and durability performance targets in all types of automotive engines

The present disclosure relates to the discovery of certain ashless antiwear additives in the form of dialkyl dithiophosphate triester compounds having specific oxygen ester moieties and a specific sulfur ester moiety that combine to provide an antiwear additive that achieves performance in lubricants without the need for (or with reduced levels of) metals provided by more traditional metal-based antiwear additives. Thus, the ashless antiwear additives of the present disclosure can supplement and/or replace traditional ZDDP additives used in lubricants and still achieve desired wear and durability performance targets in all types of automotive engines