An obesity treatment apparatus comprises at least one operable stretching device implantable in an obese patient and adapted to stretch a portion of the patient's stomach wall, and an operation device for operating the stretching device when implanted to stretch the stomach wall portion such that satiety is created.

Valve assemblies for use with expandable devices that are positioned within remote cavities and more particularly relates to the catheters/conduits used to inflate these devices with fluid.

A gastric outflow device is described. The gastric outflow device includes a ring having a ring aperture; and a topper having a topper aperture, the topper attachable to the ring, the topper aperture alignable with the ring aperture to form the gastric outflow device aperture. The gastric outflow device aperture can be adjusted wirelessly, percutaneously, by replacing the topper, and/or by including an expandable compartment surrounding the aperture, the expandable compartment increasing and decreasing the gastric outflow device aperture on being filled with filling material and having the filling material extracted, respectively.

Various devices, systems, and methods that can be used in the treatment of obesity and related illnesses are disclosed. In some instances, the cecum of an obese patient is distended to a pathophysiological size for a therapeutically effective period. The distention may be achieved by introduction of an object that is of foreign origin relative to the body of the patient into the cecum of the patient. In some instances, the distention is achieved by a medical device that transitions from an undeployed state, in which the medical device is introduced into the cecum of the patient, to an expanded state in which the medical device distends the cecum by an amount sufficient to trigger a colo-gastric brake in the patient.

An intestinal barrier sleeve release system includes a tubular housing having a first opening at one end and a second opening at the other end. A tubular sleeve to be released is disposed in the housing. A release body connected to the one end of the tubular sleeve is disposed at the first opening of the housing and is made of a material that can be dissolved and absorbed in human intestines. An inner sheath, a middle sheath and an outer sheath are sequentially set and move relative to each other. The inner sheath and the middle sheath are operated to move axially, the release body is disengaged from the housing, and the tubular sleeve moves out of the housing and is released at a specified position of the human intestines.

Systems and methods for anchoring and restraining gastrointestinal prostheses are disclosed. In various examples, the systems and methods include securing a gastrointestinal device within a patient's anatomy by extending an anti-migration anchor through a plurality of portions of the gastrointestinal device to couple together the plurality of portions of the gastrointestinal device. In some examples, the anti-migration anchor extends through tissue situated between the plurality of portions of the gastrointestinal device.

A device for implanting an inflatable intra-gastric balloon for implanting the intra-gastric balloon into a stomach, comprising: —an elastically deformable sheath configured to receive the intra-gastric balloon in the deflated state, the sheath comprising a side wall, —a tube configured to be supplied with a fluid and to cause the fluid to inflate the intra-gastric balloon, the tube comprising a mouthpiece, the intra-gastric balloon being attached to the mouthpiece in the deflated state and being detached from the mouthpiece in the inflated state, the mouthpiece having an inflation position wherein the mouthpiece extends in the cavity of the sheath, and the side wall of the sheath having a side opening configured to release the intra-gastric balloon from the cavity when the intra-gastric balloon moves from the deflated state to the inflated state.

The invention relates to a method and apparatus for endoscopically shaping and standardizing the size of a sleeved stomach for use in gastric reduction surgery. The device and method standardize and streamline gastric reduction surgery, specifically vertical sleeve gastrectomy, providing a guide for creating the stomach reduction and also shaping a stomach which will maintain an appropriate structure post-surgery.

An intraluminal device and method of fixation of an intraluminal device to resist distal migration in a mammalian lumen or hollow organ that is subject to peristalsis, according to an aspect of the invention, includes spaced apart wall portions connected with a connector. The wall portions are configured to the size and shape of a portion of the lumen or hollow organ and the connector is configured to be positioned against a wall of the lumen or hollow organ. The intraluminal device is positioned in a mammalian lumen or hollow organ that is subject to peristalsis. The device is fixed in the lumen or hollow organ against distal migration, wherein tissue lining the lumen or hollow organ bridges over the connector. The device is explanted after tissue bridges over the connector including separating the connector from one or both of the wall portions and withdrawing the connector axially from the tissue bridging over the connector.

A gastrointestinal device for treating obesity includes a three-dimensional porous structure configurable between a compressed pre-deployment configuration to facilitate delivery and an expanded post-deployment configuration. The porous structure includes a first opening at its proximal end and a larger second opening at its distal end. The porous structure also includes a sleeve coupled to its distal end. Optionally, the device further includes a suture at the proximal end of the wire mesh structure to facilitate retrieval and an anti-migration component positioned at the junction of the porous structure with the sleeve. The porous structure is deployed in a patient’s stomach such that the anti-migration component sits proximal to the patient’s pylorus and prevents migration of the entirety of the device into and through the pylorus. The sleeve extends through the pylorus, into the duodenum and ends in the duodenum or jejunum. Food enters the device from the first opening at the proximal end of the porous structure, passes through the porous structure and sleeve, and exits at the distal end of the sleeve. The device treats obesity by providing a relatively immovable volume occupying structure in the stomach and a bypass for food past the pylorus and proximal portion of the small intestine. Optionally, the device further acts to slow the passage of food through the digestive tract. Patients with the device experience satiety more quickly and have a prolonged sensation of satiety.