A retrieval device comprising a hook assembly and a capsule assembly. The hook assembly has an attachment feature at a first end. The capsule assembly includes a capsule, a capsule shaft, and a handle connected in series and defining an inner bore. The capsule has a first end defining an opening. The inner bore of the capsule assembly is configured to slidably receive the hook assembly. The handle has a central portion, a first extension portion attached to the capsule shaft, and a second extension portion with a hook assembly lock at a second end. The hook assembly lock is configured to lock the hook assembly to the second extension portion. The second extension portion is configured to pull the hook assembly relative to the capsule shaft, and the first extension portion is configured to push the capsule shaft relative to the hook assembly along the central longitudinal axis.

The present invention provides delivery systems for positioning a gastrointestinal implant in a patient, for example, for treatment of a metabolic disease. Also provided are methods for assembling the delivery systems, methods of positioning a gastrointestinal implant, and methods of treatment of metabolic diseases, such as type 2 diabetes, non-alcoholic steatohepatitis (NASH), non-alcoholic fatty liver disease (NAFLD), obesity, and related comorbidities thereof.

The invention relates to a transpyloric device for accepting chyme from the stomach and conducting said chyme on in a bypass-like manner through a patient's duodenum; said device is held in place by balloon segments which sit on a preferably radially collapsible and self-erecting transpyloric conducting element; the filling level of the balloon segments, and thus the axial sealing force acting primarily on the shoulder surfaces of the pylorus or the surrounding area thereof, can be adjusted by the user, and the force applied to the stomach and duodenum structures adjoining the pylorus is reduced to a level that is permanently bearable for the organs even when the filling pressure of the segments rolling against each other is elevated. The invention also relates to an applicator for putting a bypass device of said type in place in the region of the transition from the stomach to the duodenum.

A gastroscopic method and instrument for treating obesity of a patient, using a device adapted to stretch a part of the stomach wall of said patient. The method comprises the steps of: inserting the device into the stomach through the esophagus, placing the device in contact with the stomach wall, and fixating the device to the stomach wall such that the device can stretch a part of the stomach wall.

A system for delivering an endolumenal device through an endoscope includes a delivery tool and an adaptor. The delivery tool has an elongate tube configured to hold a portion of the endolumenal device therein and a first connecting feature on a distal end of the elongate tube. The adaptor is configured to attach to a handle of the endoscope. The adaptor includes a channel therethrough and a second connecting feature configured to mate with the first connecting feature of the delivery tool. The elongate tube of the delivery tool is configured to align with the channel of the adaptor when the first and second connecting features are mated.

The invention relates to a device for inserting an inflatable balloon which comprises a main body of revolution (12) which defines a cone-shaped distal end and a proximal end, said main body also comprising: a first internal channel (123) passing from the proximal end to the distal end of said body for inserting a thread (3) for guiding said device; an internal compartment (125) arranged in a portion of the distal end of said body for housing an inflatable balloon (4), said compartment comprising a breakable outer surface (1251) which is continuous with the surface of said body, and a second internal channel passing from the distal end of said body to said compartment, for housing a balloon inflation tube (5) suitable for connection at the distal end thereof with an inflatable balloon inside said compartment.

Apparatus (90) is provided for use in a stomach of a subject. The apparatus includes a balloon (92), adapted for placement in the stomach, and an anchor (102), coupled to the balloon. The anchor is adapted to prevent the balloon from passing into a duodenum of the subject. The apparatus further includes an inflation tube (96), coupled to the balloon to permit inflation of the balloon, and is adapted to stretch from the stomach to a mouth of the subject to facilitate inflation of the balloon. Other embodiments are also described.

A minimally invasive system and method for providing weight loss by inducing the feeling of satiety whereby an intragastric device is inserted into the gastric lumen via the esophagus and an external magnetic device is used as needed to magnetically attract the intragastric device towards the inner wall of the stomach and impart tactile stimulation sufficient to induce the feeling of satiety.

Devices and methods for treating obesity are provided. More particularly, intragastric devices and methods of tracking and locating the same are provided.

A gastrointestinal device and method for retrieving the device are disclosed. The device may include a stent including a plurality of strands forming first and second ends, the strands configured to move between a retrieval configuration, with substantially parallel strands, and a deployed configuration, wherein the strands form proximal and distal portions having first and second diameters larger than the pyloric sphincter. The device may include a connector assembly including proximal, middle, and distal connectors. The middle connector may be coupled to the proximal and distal connectors when the strands are in the deployed configuration. The strands may be attached to the proximal and distal connectors and the first and second ends. The device may include a release mechanism configured to decouple the proximal connector from the middle connector. Decoupling of the proximal and middle connectors may allow the strands to move from the deployed to retrieval configuration.