It is intended to provide a novel bisphosphonic acid compound or a salt thereof which shows a remarkable inhibitory effect on ectopic calcification, and a pharmaceutical composition comprising the same. The present invention provides a bisphosphonic acid compound represented by the following formula (1) or a pharmaceutically acceptable salt thereof:

##STR00001##

wherein represents a single bond or a double bond; A represents a saturated cyclic hydrocarbon or a saturated heterocyclic ring comprising a sulfur atom or an oxygen atom; and R.sup.1 and R.sup.2 each independently represent an alkyl group, an alkenyl group, an alkynyl group, an alkoxy group, an aryloxy group, a haloalkoxy group, a haloalkyl group, a halogen atom or a hydrogen atom.

An electrochromic element including a first electrode, second electrode facing the first electrode with gap, electrolyte layer between the first and second electrodes, and layer including a compound represented by General Formula (1) where the layer is on or above the first electrode, ##STR00001##
where R.sub.1 to R.sub.4 are each a monovalent organic group wherein no hydrogen atom is at a benzyl site where the monovalent group may include a polymerizable functional group; and R.sub.5 to R.sub.28 are each a hydrogen atom, alkyl or alkoxy group where R.sub.25 and R.sub.28, or R.sub.26 and R.sub.27 may be bonded to form a structure represented by General Formula (2), ##STR00002##
where R.sub.29 and R.sub.30 are each an alkyl, alkoxy or aryl group, and R.sub.29 and R.sub.30 may be bonded via a common bond to form a cyclic structure when R.sub.29 and R.sub.30 are aryl groups.

Methods for stabilizing one or more peroxide compounds in solution comprising adding to the solution an effective amount of at least one compound selected from the group comprising (i) cyclic carbonates; (ii) poly-phosphonic acid chelating agents and salts thereof, and alkaline pH adjusting agents with a pKb value of up to 3.0, wherein the w/w ratio of the poly-phosphonic acid chelating agent or salt thereof to alkali or alkaline earth metal hydroxide is from about 1:1 to about 50:1; and (iii) mixtures thereof. Also disclosed are solutions comprising the above compounds, uses of the above compounds to stabilize peroxide compounds in solutions, and compounds recited above for use as novel stabilizers.

Disclosed herein is a material comprising a functionalized solid support surface, wherein the functionalization comprises a thioalkylene linker bound to the support surface and the thioalkylene linker is coupled to a moiety derived from a ligand, wherein the ligand includes a terminal alkenyl and at least one first functional group configured to bind to at least one predetermined target species.

An electrode suitable for constructing an electrochemical double layer capacitor and/or supercapacitor is provided that includes an electrode material a metal organic framework (MOF), wherein the MOF includes an inorganic building unit including metal atoms selected from group 1 to group 12 elements, and functional groups of organic linkers including oxygen (O) and one or more atoms selected from the group comprising phosphorus (P), arsenic (As), antimony (Sb), silicon (Si), selenium (Se) and bismuth (Bi). The functional groups of the organic linkers can include phosphonate, arsonate, phosphonic acid, phosphinic acid, arsonic acids and/or arsenic acids, monoester and/or diester forms thereof. Further, the metal atoms may be selected from zinc (Zn), cadmium (Cd), copper (Cu), cobalt (Co), nickel (Ni), gold (Au) and silver (Ag). The use of the MOF as a semiconductor in semiconductor applications, a semiconductive device, such as a photovoltaic cell, including the MOF are also provided.

The disclosed subject matter relates compounds of structure (I), and polymers of structure (II) having a polydispersity ranging from 1 to about 1.1, compositions comprising said polymers and a spin casting solvent, the process of forming a pinning layer selectively on metal with said composition and the process of using said pinning layers to affect chemoepitaxy directed self-assembly of an overlying block copolymer, and the subsequent process of pattern transfer of this self-assembled layer into a substrate by etching.

##STR00001##

A coordination complex comprising a phosphonate-containing ligand molecule and a bioactive metal is provided. In one aspect, the present disclosure provides a compound comprising one or more phosphonate-containing ligand molecules and a bioactive metal, wherein each ligand is coordinated to the bioactive metal through at least one phosphonate, wherein the bioactive metal is Mg.sup.2+, Ca.sup.2+, or Zn.sup.2+.