The present invention provides a phosphorus-containing compound characterized by being a compound represented by the following structure: ##STR00001## the compound is a novel immune cell migration inhibitor. The compound has good hydrophilicity and can be developed into eye drops. The compound has a strong inhibitory ability to immune cell migration and can relieve the symptoms of most dry-eye patients.

The present application relates to a compound of Chemical Formula 1 and an organic light emitting device including the same.

The present invention is directed to a semiconducting material comprising: i) a compound according to formula (I) wherein R.sup.1, R.sup.2 and R.sup.3 are independently selected from C.sub.1-C.sub.30-alkyl, C.sub.3-C.sub.30 cycloalkyl, C.sub.2-C.sub.30-heteroalkyl, C.sub.6-C.sub.30-aryl, C.sub.2-C.sub.30-heteroaryl, C.sub.1-C.sub.30-alkoxy, C.sub.3-C.sub.30-cycloalkyloxy, C.sub.6-C.sub.30 aryloxy, and from structural unit having general formula E-A-, wherein—A is a C.sub.6-C.sub.30 phenylene spacer unit, and—E is an electron transporting unit that is selected from C.sub.10-C.sub.60 aryl and C.sub.6-C.sub.60 heteroaryl comprising up to 6 heteroatoms independently selected from O, S, P, Si and B and that comprises a conjugated system of at least 10 delocalized electrons, and—at least one group selected from R.sup.1, R.sup.2 and R.sup.3 has the general formula E-A-; and ii) at least one complex of a monovalent metal having formula (II) wherein—M.sup.+ is a positive metal ion bearing a single elementary charge, and each of A.sup.1, A.sup.2, A.sup.3 and A.sup.4 is independently selected from H, substituted or unsubstituted C.sub.6-C.sub.20 aryl and substituted or unsubstituted C.sub.2-C.sub.20 heteroaryl, wherein a heteroaryl ring of at least 5 ring-forming atoms of the substituted or unsubstituted C.sub.2-C.sub.20 heteroaryl comprises at least one hetero atom selected from O, S and N. ##STR00001##

A compound has a structure of Formula (I) below, wherein E represents a 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide functional group or a diphenylphosphine oxide functional group. Moreover, a method of making the compound of Formula (I), a resin composition including the compound of Formula (I) and a resin additive and an article made from the resin composition are described. The article includes a prepreg, a resin film, a laminate or a printed circuit board, wherein one or more properties including copper foil peeling strength, Z-axis ratio of thermal expansion, glass transition temperature, flame retardancy, thermal resistance after moisture absorption, dielectric constant, and dissipation factor may be improved.

##STR00001##

The present invention relates to an organic compound of formula (1), suitable for use as a layer material for electronic devices, and it relates to an organic semiconductor layer comprising at least one compound thereof, as well as to an organic electronic device comprising at least one organic semiconductor layer, and a method of manufacturing the same.

##STR00001##

An organosilicon compound having not more than 200 silicon atoms per molecule is provided. The organosilicon compound is represented by the following average compositional formula (I): Y.sub.aR.sup.1.sub.bSiO.sub.(4-a-b)/2 wherein R.sup.1 is an alkyl group having 1 to 12 carbon atoms, alkenyl group having 2 to 12 carbon atoms, aryl group having 6 to 20 carbon atoms, alkoxy group having 1 to 6 carbon atoms, or a hydroxyl group; Y is a specific acylphosphinate residue; and subscripts a and b are numbers satisfying the following conditions: 0<a≤2, 0<b≤3, and a≤b. The organosilicon compound is compatible with organopolysiloxanes and is useful as a photo-initiator for various types of photo-curable compositions.

The present disclosure provides compounds and methods for inhibiting the interaction of menin with its upstream or downstream signaling molecules including but not limited to MLL1, MLL2 and MLL-fusion oncoproteins. Compounds of the disclosure may be used in methods for the treatment of a wide variety of cancers and other diseases associated with one or more of MLL1, MLL2, MLL fusion proteins, and menin.

Provided herein are inhibitors of MEK kinase, pharmaceutical compositions comprising said inhibitory compounds, and methods for using said MEK kinase inhibitory compounds for the treatment of disease.

The present disclosure relates to display technologies, and particularly discloses an organic electroluminescent device. This organic electroluminescent device includes a light-emitting layer, the light-emitting includes an exciplex composed of a donor molecule and an acceptor molecule, and a wide band gap material for increasing the inter-molecular spacing between the donor molecule and the acceptor molecule. According to the device of the present disclosure, the degree of orbital overlap of HOMO and LUMO of the formed exciplex and the singlet-triplet energy level difference can be reduced, the reverse intersystem crossing rate (k.sub.RISC) of the exciplex host can be increased, the Föster energy transferred to the guest molecule can be enhanced, and the efficiency and the lifetime of the device can be improved.

A compound has a structure of Formula (I) below, wherein E represents a 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide functional group or a diphenylphosphine oxide functional group. Moreover, a method of making the compound of Formula (I), a resin composition including the compound of Formula (I) and a resin additive and an article made from the resin composition are described. The article includes a prepreg, a resin film, a laminate or a printed circuit board, wherein one or more properties including copper foil peeling strength, Z-axis ratio of thermal expansion, glass transition temperature, flame retardancy, thermal resistance after moisture absorption, dielectric constant, and dissipation factor may be improved. ##STR00001##