Patent classifications
C07F9/65517
AROMATIC COMPOUNDS
The present invention relates to a compounds of formula I
R.sup.1-(A.sup.1-Z.sup.1).sub.r—B.sup.1—Z.sup.L-A.sup.2-(Z.sup.3-A.sup.3).sub.s-G (I)
in which the occurring groups and parameters have the meanings given in claim 1, to the use thereof for the formation of molecular layers, in particular self assembled monolayers, to a process for the fabrication of a switching element for memristive devices comprising said molecular layers and to a memristic device comprising said switching element.
Semiconducting material and naphthofurane matrix compound for it
The present invention relates to a semiconducting material comprising an electron transport matrix compound comprising at least one electron transporting structural moiety and at least one polar structural moiety; a matrix compound and electronic device utilizing the semiconducting material.
Antibody-nanoparticle conjugates and methods for making and using such conjugates
Disclosed herein are antibody-nanoparticle conjugates that include two or more nanoparticles (such as gold, palladium, platinum, silver, copper, nickel, cobalt, iridium, or an alloy of two or more thereof) directly linked to an antibody or fragment thereof through a metal-thiol bond. Methods of making the antibody-nanoparticle conjugates disclosed herein include reacting an arylphosphine-nanoparticle composite with a reduced antibody to produce an antibody-nanoparticle conjugate. Also disclosed herein are methods for detecting a target molecule in a sample that include using an antibody-nanoparticle conjugate (such as the antibody-nanoparticle conjugates described herein) and kits for detecting target molecules utilizing the methods disclosed herein.
Stabilized Polyolefin Compositions Comprising Benzofuranones and Hindered Phenolic Antioxidants
Polyolefin compositions comprising i) a polyolefin, ii) one or more phosphorus-containing benzofuranone compounds and iii) one or more hindered phenolic antioxidants are provided excellent protection against discoloration and enhanced thermal stability during melt processing as exhibited by improved retention of molecular weight and maintenance of polymer molecular architecture.
Phosphorus-containing compound and preparation and use thereof
The present invention provides a phosphorus-containing compound characterized by being a compound represented by the following structure: ##STR00001## the compound is a novel immune cell migration inhibitor. The compound has good hydrophilicity and can be developed into eye drops. The compound has a strong inhibitory ability to immune cell migration and can relieve the symptoms of most dry-eye patients.
Semiconducting material comprising a phosphine oxide matrix and metal salt
The present invention is directed to a semiconducting material comprising: i) a compound according to formula (I) wherein R.sup.1, R.sup.2 and R.sup.3 are independently selected from C.sub.1-C.sub.30-alkyl, C.sub.3-C.sub.30 cycloalkyl, C.sub.2-C.sub.30-heteroalkyl, C.sub.6-C.sub.30-aryl, C.sub.2-C.sub.30-heteroaryl, C.sub.1-C.sub.30-alkoxy, C.sub.3-C.sub.30-cycloalkyloxy, C.sub.6-C.sub.30 aryloxy, and from structural unit having general formula E-A-, wherein—A is a C.sub.6-C.sub.30 phenylene spacer unit, and—E is an electron transporting unit that is selected from C.sub.10-C.sub.60 aryl and C.sub.6-C.sub.60 heteroaryl comprising up to 6 heteroatoms independently selected from O, S, P, Si and B and that comprises a conjugated system of at least 10 delocalized electrons, and—at least one group selected from R.sup.1, R.sup.2 and R.sup.3 has the general formula E-A-; and ii) at least one complex of a monovalent metal having formula (II) wherein—M.sup.+ is a positive metal ion bearing a single elementary charge, and each of A.sup.1, A.sup.2, A.sup.3 and A.sup.4 is independently selected from H, substituted or unsubstituted C.sub.6-C.sub.20 aryl and substituted or unsubstituted C.sub.2-C.sub.20 heteroaryl, wherein a heteroaryl ring of at least 5 ring-forming atoms of the substituted or unsubstituted C.sub.2-C.sub.20 heteroaryl comprises at least one hetero atom selected from O, S and N. ##STR00001##
3-phenyl-benzofuran-2-one diphosphate derivatives as stabilizers
The invention relates to a composition comprising an organic material susceptible to oxidative, thermal or light-induced degradation and a compound of formula I-P, I-O or I-M. Further embodiments are a compound of formula I-P, I-O or I-M, a process for protection of the organic material by the compound, the use of the compound against degradation of the organic material, an additive composition comprising the compound, processes for manufacturing the compound and an intermediate involved therein. ##STR00001##
CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS
Disclosed herein, inter alia, are prodrug compositions and methods of using the same for treatment and detection of disease. Specifically, disclosed herein is a compound of formula (I) having spiro-fused 1,2,4-trioxolane and piperidine rings, namely, 1,2,4-trioxa-8-azaspiro[4.5] decane. Also disclosed is a pharmaceutical composition containing the compound and a pharmaceutically acceptable carrier.
##STR00001##
LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS
The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a provided lipid prodrug or a pharmaceutical composition thereof.
Compound for electron-transport material and organic light emitting diode including the same
Disclosed herein is a compound for electron transport material and an organic light emitting diode including the same. The compound for electron transport material is represented by the following Formula 1. Since the compound for electron transport material, as represented by Formula 1, contains a triazine structure, the compound has high electron mobility and is thus suitable as an electron transport material. The organic light emitting diode includes an electron transport layer formed of the compound as represented by Formula 1 and thus can have increased lifespan. ##STR00001##