A medical device for repositioning tissue within an animal has a main body with a first end portion, a second end portion, and a middle portion. The first end portion defines a series of passageways and the second end portion defines a bulbous shape, a slot, and a tab portion. Methods of treating obstructive sleep apnea are also described.

A method, system, apparatus, and/or device for adjusting a mandible of a user. The method, system, apparatus, and/or device may include: a top tray configured to be inserted into a mouth of a user to form around upper teeth of the user; a top position adjuster attached to a bottom portion of the top tray: a bottom tray configured to be inserted into the mouth of the user to form around lower teeth of the user; and a bottom position adjuster attached to a top portion of the bottom tray, where the top position adjuster and the bottom position adjuster are adjustable to move the top position adjuster or the bottom position adjuster laterally or longitudinally.

A method and system to prevent sore throat infections in humans includes the administration of an active ingredient to a site on the mucus membranes of the throat of a human that inhibits adherence and promotes desorption of S. pyogenes to soft tissue surfaces, such as the pharyngeal and oral mucosa of a human. A mucoadhesive strip having a surface topography that resists bioadhesion of undesired bacteria that are typically present in a human's mouth is preferably employed and that has one or more encapsulated agents selected from the group consisting of an antibiotic; lactic acid bacteria; S. pyogenes modified by a CRISPR-Cas system to reduce one or more virulence factors; and a breath mint solution.

This invention presents an intraoral device for generation of contact perception between teeth, the device being configured for application to the upper or lower dental arch of a user and comprising a contact means (20, 20′) configured to be associated with at least a portion of one to four posterior teeth (D1) of the upper or lower dental arch, the device (10) being configured to generate a perception of contact to the user upon the contact between the contact means (20, 20′) and at least a portion of the opposing arch to at least a portion of one to four posterior teeth (D1), offering the option of an accessible intraoral device for practical use to the user, and that does not impair the mouth functions of the user during its use in the waking period. This invention further comprises a method of applying the device which allows the user to apply the device without assistance of a skilled professional, and a method for determining the thickness of the aforesaid device.

The present invention is a holding case for an instrumented intra-oral appliance containing recorded data, which charges the intra-oral appliance while not in use and transmits recorded data to storage for review and analysis. The transferred data may be subjected to downloading, validation, storage, analysis, measuring, database fusion (with for example data from other devices), data output, and data recording. Output may be further transferred to a computer, processor, phone, tablet computer, or other hardware for review by a user or technical, research, medical, or other oversight personnel. The holding case can also send data to the appliance including firmware or other onboard operating instructions. The holding case can include additional features such as custom dentition of the user, UV light, or a visual user interface.

Methods and systems herein relate to forming an upper dental appliance chassis including at least two upper appliance button protrusions; forming a lower dental appliance chassis including at least two lower appliance button protrusions and at least two vertical displacement bite pads; injection overmolding a first thermoplastic on the upper dental appliance chassis to provide a first reformable thermoplastic layer integrated with the upper dental appliance chassis that exposes the at least two upper appliance button protrusions to form an upper dental tray; and injection overmolding a second thermoplastic on the upper dental appliance chassis to provide a second reformable thermoplastic layer integrated with the lower dental appliance chassis that exposes the at least two lower appliance button protrusions and the at least two vertical displacement bite pads to form a bottom dental tray.

Maxillary and mandibular appliances can be mounted to a user's upper and lower jaws. The appliances can include a palatal pad, buccal tubes, hamular notch tubes, and an anterior deprogrammer. The various portions of the appliances can provoke beneficial reactions by muscles in the tongue and jaw area, massage the same muscles, or provide other beneficial effects.

An implantable neurostimulator (INS) and method of use, the INS including an electrical lead having formed thereon at least a pair of bi-polar electrodes, wherein the electrical lead is configured for placement of the pair of bi-polar electrodes proximate protrusor muscles of a patient, a pulse generator electrically connected to the electrical lead and configured to deliver electrical energy to the pair of bi-polar electrodes, the pulse generator having mounted therein a sensor and a control circuit, and the sensor is configured to generate signals representative of an orientation of the pulse generator and communicate the signals to the control circuit and the control circuit is configured to determine the orientation of the pulse generator and deliver electrical energy to the bi-polar electrodes when the determined orientation correlates to a pre-determined orientation.

Methods and systems herein relate to receiving dentition data of a patient; processing the dentition data in a server to determine a vertical displacement and a forward mandibular position to enable the patient to breathe during sleep by opening the airway of the patient; and forming a homogeneous dental appliance via direct manufacture using the processed dentition data, the vertical displacement and the forward mandibular position, the dental appliance including a lower dental tray and an upper dental tray, the lower dental tray inclusive of a pair of vertical displacement bite pads with the vertical displacement and a first pair of button protrusions, the upper dental tray inclusive of a second pair of button protrusions, the first pair of button protrusions and the second pair of button protrusions providing the forward mandibular position when two elastic bands are attached to connect the upper dental tray and the lower dental tray.

A mouthpiece including a constituent portion (X) that includes an olefin-based polymer (A) having a repeating unit having 2 or 3 carbon atoms and that satisfies a bending elastic modulus (α) at 23° C. of 80 MPa≤α≤1000 MPa.