An intrauterine device and method of delivering and using same are provided. The intrauterine device includes a wire having a portion capable of forming a three dimensional (3D) structure. The 3D structure is elastically deformable to a partially collapsed configuration via a crush force larger than a force applied thereto by a relaxed uterine cavity. The three dimensional structure is also capable of elastically contracting and expanding in response to contraction and expansion of the uterine cavity.

An intrauterine device and method of delivering and using same are provided. The intrauterine device includes a wire having a portion capable of forming a three dimensional (3D) structure. The 3D structure is elastically deformable to a partially collapsed configuration via a crush force larger than a force applied thereto by a relaxed uterine cavity. The three dimensional structure is also capable of elastically contracting and expanding in response to contraction and expansion of the uterine cavity.

The present invention is related to a vaginal drug delivery device and to a vaginal diagnostic device that comprises a first and second rigid member, wherein the first and/or second rigid member comprises a reservoir holding a medicament to be delivered, an opening, and a pump for pumping said medicament out of said opening, and/or wherein the first rigid member and/or second rigid member comprises a diagnostic device for performing an intravaginal diagnosis or measurement therefor.

The device further comprises a first flexible member and flexible part, wherein at least one of the first flexible member and the flexible part is at least partially elastic having an elasticity such that the device can be squeezed from an extended shape to a collapsed shape. The device is pre-biased to assume the extended shape when little to no external force is being applied thereto. Furthermore, the device assumes a shape substantially corresponding to the extended shape when the device is inserted with the squeezed rigid member first, so that these naturally unfold in the formix posterior vaginae.

A method of manufacturing an intrauterine device (IUD) for contraception that has a desired copper elution rate is described. The method may involve selecting an elongate shape memory member comprising a first metal having a first galvanic potential, selecting at least one attachment member comprising a second metal having a second galvanic potential that is different from the first galvanic potential, attaching the attachment member(s) to the shape memory member, and shaping the shape memory member to form a frame of the intrauterine contraceptive device. The first metal and the second metal are specifically selected as materials for the shape memory member and the attachment member(s), in order to achieve the desired copper elution rate.

An intrauterine device (IUD) with a restricted movement of a string(s), the strings can be either a single string or two or more strings or a filament, emerging from the spherical bulge of IUD. The strings of IUD are of a differential strength so that the strings are soft and the hanging portion of the strings, “feelable” in the vaginal cavity, does not cause discomfort to the woman, nor bruise the organ of the partner during intercourse, at the same time the strings in the endocervical canal are relatively stiffer and not have the tendency to get curled up progressively. The strings optionally have marks to facilitate cutting by a surgeon to an accurate length.

A tray for securing an implantable device to a carrier member includes a slot configured to retain the carrier member and a receptacle adjacent the slot. The carrier member surrounds a shaft of the implantable device. The receptacle has a first width at a proximal end of the receptacle to receive first and second arms of the implantable device in an initial state in which the first and second arms extend substantially perpendicularly from the shaft. The receptacle has a second width at a distal end of the receptacle for receiving the first and second arms of the implantable device in a collapsed state in which the first and second arms are folded against the shaft such that the carrier member can be slid over the first and second arms to retain the first and second arms. The second width is less than the first width.

An everting balloon system is disclosed that can be used for the placement of an IUD within the uterine cavity of a female patient. The everting balloon system with IUD can be used to access a uterine cavity at specific locations in the fundus. A one-handed IUD delivery system for placement with an everting catheter is disclosed. An IUD loading system for placement within an everting catheter is disclosed. The everting catheter with an IUD can simplify the process of IUD placement within the uterine cavity.

A method for promoting contraception by placing a contraceptive device within a uterus without blocking fallopian tubes may involve advancing a distal end of a delivery device through a cervix, advancing the contraceptive device comprising an elongate shape memory member out of the distal end of the delivery device and into the uterus, and limiting inferior migration of the contraceptive device within the uterus. Inferior migration may be limited by allowing the contraceptive device to assume a shape, when subjected to pressure that tends to cause a downward migration of the device within the uterus, in which an expandable middle portion of the device is expanded to contact the inner wall of the uterus and thus limit the downward migration of the device.

A process for recovering one or more blastocysts from a uterus of a human includes a step of placing a device transvaginally into a cervical canal of the patient; a step of delivering fluid through the device to the uterus and applying a vacuum to a uterus of the patient to aspirate fluid and entrained one or more blastocysts from the uterus; and a step of performing a biopsy procedure on the one or more recovered blastocysts to remove one or more of trophectoderm cells or inner cell mass from the recovered blastocysts. The process may further include a step of storing one or more of the biopsied trophectoderm cells or inner cell mass following the biopsy procedure and a step of performing at least one molecular diagnostic assay test on the one or more of the biopsied trophectoderm cells or inner cell mass.

A method of manufacturing an intrauterine device (IUD) for contraception that has a desired copper elution rate is described. The method may involve selecting an elongate shape memory member comprising a first metal having a first galvanic potential, selecting at least one attachment member comprising a second metal having a second galvanic potential that is different from the first galvanic potential, attaching the attachment member(s) to the shape memory member, and shaping the shape memory member to form a frame of the intrauterine contraceptive device. The first metal and the second metal are specifically selected as materials for the shape memory member and the attachment member(s), in order to achieve the desired copper elution rate.