The present invention provides a POSS-containing in-situ composite nanogel with magnetic responsiveness and the method for preparing the same, wherein POSS-containing macromolecule capable of polymerizing and metal-coordination complexing is synthesized to complex with iron salt, Fe.sup.2+/Fe.sup.3+ salts are in-situ deposited via chemical coprecipitation, and crosslinking agent and initiator are added to induce polymerization so that POSS-containing nanogel ranges with magnetic responsiveness is obtained. The present invention is of professional design, feasible technique and simple operation, and prepared nanogel magnetic particles are well dispersed with excellent magnetic responsiveness, which possesses a good application prospect in medical diagnosis, sensor, catalyst carrier and biomaterial.

Disclosed is a process for manufacturing copolyether ester polyol comprising: (1) providing feedstock comprising polytetramethylene ether glycol having a number average molecular weight of 350 g/mol or less and an oligomeric cyclic ether content of 4.0% by weight or more and a diacid composition selected from alpha-omega alkanedioic acids of formula HO.sub.2C—(CH.sub.2).sub.n—CO.sub.2H, where n is from 2 through 16 to a reaction zone maintained at reaction conditions to produce a crude polyol product; (2) feeding the crude polyol product of step (1) to a separation zone at separation conditions to produce a first separation product having an oligomeric cyclic ether content of 2.0% by weight or greater, and a second separation product comprising copolyether ester polyol having an oligomeric cyclic ether content of less than 2.0% by weight; and (3) recovering the second separation product.

A polymer film can be adjusted to movement or a fine uneven surface of a living body and has excellent ability to adhere to a biological tissue. The polymer film includes a block copolymer having a structure in which branched polyalkylene glycol and polyhydroxyalkanoic acid are bound to each other, wherein the polymer film has a film thickness of 10 to 1000 nm. The branched polyalkylene glycol has at least three terminal hydroxyl groups per molecule, the mass percentage of the branched polyalkylene glycol relative to the total mass of the block copolymer is 1% to 30%, and a value obtained by dividing the average molecular weight of polyhydroxyalkanoic acid in the block copolymer by X that is the number of terminal hydroxyl groups present per a single molecule of the branched polyalkylene glycol is 10000 to 30000.

Disclosed herein are derivatives of phenolic and melamine compounds, methods of making these derivatives, and methods of using them. The compounds include phenolic and melamine compounds with multi-functional acrylate groups, polyethylene glycol and amino groups. The compounds may be cured to form resins that may be used in a variety of applications, such as paints, hydrogels, polyacrylate super absorbent polymers (SAPs), adhesives, composites, sealants, fillers, fire retardants, crosslinking agents, and the like.

Among other aspects, provided herein are multi-armed polymer conjugates comprising an alkanoate-linker, compositions comprising such conjugates, and related methods of making and administering the same. Methods of treatment employing such conjugates and related uses are also provided. The conjugates are prepared with high drug loading efficiencies.

A sample protection method is provided which may be used for protecting a biological sample on a microscope slide, such as during heat-induced target retrieval and/or after heat-induced target retrieval such that: 1) the sample remains adherent to the microscope slide; and 2) the microscopic morphology of the biological sample remains intact. In some embodiments, the sample protection method may include the steps of: creating a sectioned sample that is in contact with a microscope slide; applying a protecting reagent onto a sectioned sample that is in contact with a microscope slide and drying the protecting reagent in which the protecting reagent may be both applied and dried onto the sectioned sample before and/or after performing target retrieval on the sectioned sample. The protecting reagent may include a water-soluble polymer and/or a water-soluble wax, such as polyethylene glycol, polypropylene glycol, polyvinyl alcohol, polyvinylpyrrolidone, alginic acid, and carrageenan.

The invention relates to a process for preparing a polyoxyalkylene carbonate polyol by reacting a polyoxyalkylene polyol with a cyclic carbonate in the presence of an amine catalyst. The invention further relates to polyoxyalkylene carbonate polyols obtainable using the method according to the invention and to a process for preparing polyurethanes by reacting the polyoxyalkylene carbonate polyols according to the invention with polyisocyanates.

The present invention provides a photocured product having both excellent toughness and high strength, and also provides a photocurable composition for forming said photocured product. The present invention provides a photocurable composition comprising: A. a (meth) acrylic acid ester monomer, wherein the glass transition temperature of a polymer formed from only said monomer is 20° C. or higher; B. a polyrotaxane obtained by respectively placing blocking groups at both ends of a pseudo-polyrotaxane, which is obtained by threading a linear molecule through the hole of a cyclic molecule, so as not to release the cyclic molecule, wherein the cyclic molecule has a (meth) acrylic group; and C. a photopolymerization initiator. The present invention also provides a photocured product formed from said composition.

A curable precursor composition for a fluoroelastomers, methods of making fluoroelastomers, shaped articles and methods of making shaped articles.

A curable precursor composition for a fluoroelastomers, methods of making fluoroelastomers, shaped articles and methods of making shaped articles.