Methods and compositions are described for enhancing tissue regeneration or wound repair in a mammalian subject comprising a composition comprising (a) a proline hydroxylase inhibitor component or molecule that increases or upregulates HIF1a and (b) a carrier component comprising a hydrogel.

Provided is a carbon dioxide absorber comprising a polyether compound, wherein the polyether compound contains an average of 50 or more repeating units represented by General Formula (1) set forth in the description per molecule, and the polyether compound contains a repeating unit represented by General Formula (2) set forth in the description as at least part of the repeating units represented by General Formula (1).

Synthesis of monodisperse PEG-based microparticles with stable coupling chemistries. Biomolecules are conjugated to monodisperse PEG microparticles using non-amine chemistries, such as sulfhydryl groups, azide, or alkyne-based chemistries.