Provided is a fluorinated ether compound capable of imparting excellent antifouling properties such as oil-based ink repellency, fingerprint stain removability, to a hard coating layer; a composition for forming a hard coating layer, and an article having an antifouling hard coating layer formed from the composition. The fluorinated ether compound has either a poly(oxyperfluoroalkylene) chain having a repeated unit that includes a C.sub.1-2 oxyperfluoroalkylene group and a C.sub.3-6 oxyperfluoroalkylene group, bonded to each other, or a poly(oxyperfluoroalkylene) chain having a repeated unit that contains a C.sub.4 oxyperfluoroalkylene group and a different oxyperfluoroalkylene group, bonded to each other, a linking group bonded to a first terminal of the poly(oxyperfluoroalkylene) chain, and at least one (meth)acryloyl group bonded to the linking group.

There is provided an anti-angiogenic agent comprising: a multi-block copolymer in the form of one or more micelles, wherein the copolymer comprises a first poly (alkylene glycol) block, a second poly (alkylene glycol) block and a polyester block. There is also provided a method of preparing said anti-angiogenic agent and medical uses of said anti-angiogenic agent.

To provide a fluorinated compound capable of obtaining a cured product which is excellent in heat resistance and mold release and has a high Abbe number; a curable composition containing such a compound; and a cured product which is excellent in heat resistance and mold release and has a high Abbe number. The fluorinated compound is represented by the following formula (A):

[ZOCH.sub.2CF.sub.2CF.sub.2CF.sub.2OCFHCF.sub.2X-].sub.nQ(A)

where n is an integer of at least 1, Q is a n-valent organic group, X is O, NH or S, and Z is a group having at least one polymerizable functional group.

This disclosure relates to new injectable hydrogel materials that consist of water gellants comprising linear hydrophilic polymers that comprise hydrogen bonding units in the backbone combined with cross-linkable end groups, resulting in dynamic yet firm hydrogel materials that are easily processable, are highly elastic, show adhesive properties and are self-healing and are especially suitable for biomedical applications.

Various embodiments provide epoxy modified fluorinated urethane compositions that may provide desirable bulk mechanical properties of conventional coatings, adhesives, or structural matrix resins, while simultaneously exhibiting surface properties that may reduce surface contamination. Various embodiments provide formulations comprising epoxy modified fluorinated alkyl ether including urethane oligomer or polymer resins that may possess the requisite thermal, mechanical, chemical, and optical properties while achieving a low surface energy. In various embodiments, such resins may be prepared from random urethane oligomer compositions including fluorinated alkyl ether segments, in which the oligomers may be terminated with amino groups and subsequently reacted with epoxy including monomers or oligomers.

A composition comprising linked segments of: (a) a polyhydroxy segment derived from a compound independently selected an acyclic polyhydric alcohol having 4 to 6 carbon atoms and 4 to 6 reactive hydroxyl groups; a cyclic polyhydric alcohol having 4 to 6 carbon atoms and 4 to 6 reactive hydroxyl groups, a poly(hydroxyethyl) polyethyleneamine having 4 to 6 reactive hydroxyl groups and combinations thereof; (b) polyoxyalkylene segments wherein each hydroxyl group of the polyhydroxyl segment is linked to a polyoxyalkylene segment; (d) and aliphatic end segments or aromatic end segments, each end segment having 6 to 32 carbon atoms and a hydroxyl reactive group, wherein the mole ratio of the polyoxyalkylene segment to the polyhydroxy segment is at least 4:1 and the mole ratio of the aliphatic or aromatic end segment to the polyhydroxy segment is at least 0.25:1.

The present invention provides a moisture-curing sealant comprising a) at least one silane-functional polymer and b) at least one catalyst for the crosslinking of the silane-functional polymer, said sealant being free of organotin compounds and having, in the cured state, a secant modulus at 100% elongation and 23 C., determined to ISO 8339, of less than 0.4 MPa and a resilience at 100% elongation, determined to ISO 7389, of greater than 70%. The sealant is especially suitable as a construction sealant of the 25LM class according to DIN EN ISO 11600, especially as a facade sealant, or as a sealant according to ASTM C719 Class 50.

The present invention relates to a process for the preparation of oligo(alkylene glycol)-functionalized polyisocyanopeptides comprising the steps of functionalizing an isocyanopeptide with oligo-(alkylene glycol) side chains and subsequently polymerizing the oligo-alkylene glycol-functionalized isocyanopeptides. Several isocyanopeptides may be functionalized with various linear or non-linear oligo-(alkylene glycol) side chains having variable chain length. The alkylene glycol may be selected from the group consisting of ethylene-, propylene-, butylene- or pentylene glycol. Preferably, the isocyanopeptides are functionalized with at least three ethylene glycol side chains. The peptides may comprise L-amino acids, D-amino acids or D, L-amino acids. The obtained oligoalkylene-functionalized polyisocyanopeptides are a new class of materials with unique thermo-responsive properties.

An adhesive which includes at least one silane-functional polymer P; at least one catalyst for crosslinking silane-functional polymers, the catalyst being selected from the group including organo-titanate, organo-zirconate, and organo-aluminate; at least one base; and at least one adhesive selected from alkoxy mercaptosilane and amino alkoxysilane, for filling wood joints. The adhesive filled into the joints is preferably sanded after the curing process. The adhesive exhibits a high UV stability and a stability against warm humid climates. The adhesive is therefore suitable for naval applications in particular, such as in the construction of boats and ships. The adhesive can be formulated so as to be black, white, or gray for example.

A composition comprising linked segments of: (a) a polyhydroxy segment derived from a compound independently selected an acyclic polyhydric alcohol having 4 to 6 carbon atoms and 4 to 6 reactive hydroxyl groups; a cyclic polyhydric alcohol having 4 to 6 carbon atoms and 4 to 6 reactive hydroxyl groups, a poly(hydroxyethyl) polyethyleneamine having 4 to 6 reactive hydroxyl groups and combinations thereof; (b) polyoxyalkylene segments wherein each hydroxyl group of the polyhydroxyl segment is linked to a polyoxyalkylene segment; (d) and aliphatic end segments or aromatic end segments, each end segment having 6 to 32 carbon atoms and a hydroxyl reactive group, wherein the mole ratio of the polyoxyalkylene segment to the polyhydroxy segment is at least 4:1 and the mole ratio of the aliphatic or aromatic end segment to the polyhydroxy segment is at least 0.25:1.