In a first aspect, the invention relates to a device for hyperthermal treatment of itching comprising at least one treatment surface which can be heated by heating at least one heating element to a treatment temperature of 40° C. to 65° C. and can be controlled by a control device, wherein the device exhibits at least one interface and is configured for a power supply of the device by a mobile device and/or for data exchange with a mobile device and/or for control by a mobile device via the interface.

In a further aspect, the invention relates to a system comprising the device and a mobile device, wherein the device is configured for a power supply by the mobile device and/or for data exchange with the mobile device and/or for control by the mobile device via an interface.

Methods for at least partially eradicating a target tissue by apoptosis may include reducing the temperature of a device shaft on a tissue eradication device to a target temperature, vibrating the device shaft and inducing apoptosis in the target tissue by contacting the target tissue with the device shaft or injecting a cold fluid from the cannulated device shaft of the tissue eradication device into the target tissue. Tissue eradication systems are also disclosed.

Disclosed is a multi-functional probe capable of shielding electromagnetic waves in which an ultrasonic driver circuit and an ultrasonic oscillation element are surrounded by a shielding member in a state in which the ultrasonic driver circuit and the ultrasonic oscillation element are disposed close to each other and which allows a material of a head, to which ultrasonic waves are transmitted, to be changed to a non-conductive material and prevent moisture from being introduced into the probe. To this end, the multi-functional probe includes a cover part accommodating the ultrasonic driver circuit and the ultrasonic oscillation element, a fixing part fixing the ultrasonic driver circuit and the ultrasonic oscillation element in the cover part, and a shield part configured to block electromagnetic waves generated by the ultrasonic driver circuit and the ultrasonic oscillation element.

This application relates to a cooling device that sprays a coolant received from a coolant reservoir toward a target region to cool the target region. In one aspect, the cooling device includes a spraying unit from which the coolant is sprayed, a valve configured to regulate a flow of the coolant, and a control unit configured to control opening and closing of the valve, wherein, when cooling starts. The control unit controls a first cooling mode in which a temperature of the target region is decreased and a second cooling mode in which the temperature of the target region is maintained in a predetermined temperature range to be sequentially performed.

A microenvironment of a biological body is controlled, and more particularly, is measured, changed, and monitored with respect to temperature, pH level, moisture and other tissue parameters of a region of the body while, optionally, administering a therapeutic agent to that region.

A device comprising a heat-generating component that comprises an alkali metal is provided. The alkali metal in the presence of water at a point of contact of the device undergoes an exothermic reaction to generate heat in situ. The amount of heat generated is proportional to and/or limited by the amount (or moles) of water at the point of contact, and the heat generated is sufficient to achieve an increase in temperature at the point of contact to achieve a therapeutic or beneficial result. In one embodiment, the device is used for reducing sweat production in a subject suffering from excessive sweating or hyperhidrosis. In other embodiments, the device is used to substantially sterilize a surface or render a surface substantially aseptic.

A oil treatment system, method and device are disclosed. An oil impregnated treatment pad is attachable to a carrier, with a heat pad attachable to the carrier, so as to deliver the treatment to a user with a heat source adjacent to the treatment pad.

A wearable thermometer patch for monitoring healing of a wound on a user's skin includes a circuit substrate comprising an electric circuit and a plurality of temperature probe units distributed in a two-dimensional array. Each of the plurality of temperature probe units can include a temperature sensor in electric connection with the electric circuit in the circuit substrate. The plurality of temperature probe units can measure temperature values on a user's skin at different positions defined by the two-dimensional array.

A multifunctional skin patch can be used during a treatment procedure to achieve one or more safety factors, including skin cooling, pain management, laser plume control, and/or proper application of the treatment. The multifunctional skin patch includes a transparent hydrogel layer that can be applied to a patient's skin prior to application of the treatment procedure. The treatment procedure can be conducted through the transparent hydrogel layer, and the transparent hydrogel layer (with can be pre-cooled) can cool and/or control pain within the portion of the patient's skin during and/or after the treatment procedure. In some instances, the multifunctional skin patch can also include a transparent indicator layer (covering at least a portion of the transparent hydrogel layer) with dispersed indicator particles attached thereto and/or embedded within. The indicator particles are configured to change in appearance upon application of treatment procedure through the transparent indicator layer.

A tissue treatment system includes an applicator connected with a base unit. The applicator includes a light source to generate light energy. A light guide directs the light energy to biological tissue and is configured to contact biological tissue. A thermoelectric cooler has a cold side and a hot side, with the cold side being associated with the light guide. A hot side plate is mounted to the hot side of the thermoelectric cooler. A first fluid passage is between the reservoir and the hot side plate to deliver cooling fluid over the hot side plate to chill the cold side of the thermoelectric cooler and cool the light guide and biological tissue. A second fluid passage is associated with the light source to direct cooling fluid to the light source prior to being returned to the reservoir. The first and second fluid passages define a single cooling fluid circulation loop.