An exercise assistance system includes a deep body thermometer attached to a user and including a temperature sensor, temperature adjustment equipment attached to at least one of a hand and a foot of the user, and a controller configured to communicate with the deep body thermometer and the temperature adjustment equipment. The deep body thermometer detects information related to deep body temperature of the user with the temperature sensor. The controller executes a process for determining whether the deep body temperature of the user is less than or equal to a predetermined temperature based on the detected information related to deep body temperature. When determined that the deep body temperature is not less than or equal to the predetermined temperature, the controller executes a process for outputting control information to the temperature adjustment equipment indicating a magnetic stimulating pattern that dilates blood vessels in a palm or foot bottom of the user.

Methods and system for atrial fibrillation mapping utilizing cardiac mapping based on medical image(s). The methods and system also adapted for any balloon based catheters including cryoballoon catheter, laser balloon catheter, or “hot balloon” catheter, as well as circular catheters. The methods and system includes overlaying of two or more images on top of each other (where the images are of various types or modalities) and aligning the images, where the transparency between the images can be adjusted for navigating and optimal placement of the balloon based catheters or circular catheters. The cardiac system also adopted for guiding optimal placement of the left ventricular (LV) lead placement for cardiac re-synchronization (CRT) therapy, and for mapping and displaying activation times from various branches of the coronary sinus for optimizing CRT therapy.

The present invention provides a medical emergency first aid during accidents using cervical spine collar to insert a splint for stabilization, resuscitation, initiation of mild to moderate external hypothermia, and vital signs monitoring in victims of traumatic brain (TBI) and cervical spinal injury (CSI). The cervical spine collar of the present invention is housed in the head rest of the vehicle seat and could be deployed automatically using artificial intelligence (AI) or manually by an assistant. One embodiment incorporates a protective helmet with cooling apparatus to induce mild to moderate external hypothermia of the brain to prevent deleterious effects of TBI.

A cold therapy apparatus includes a thermal body wrap with umbilical to a control unit with pump for circulating a thermal fluid to remove heat from a body. A coolant heat exchange assembly includes a coolant tank that is filled with a coolant and has a heat exchanger inside that is immersed in the coolant. The heat exchanger is coupled to the control unit to circulate the thermal fluid through the thermal body wrap. The coolant heat exchange assembly is removed from the control unit and placed in a cold environment to chill the coolant, and is then re-coupled during cold therapy. The process is repeated form extended therapy periods.

A lightweight highly portable scalp or body part cooling system to mitigate the effects of chemotherapy induced alopecia or other medical condition. The device consists of a scalp heat exchanger cap or body part heat exchanger, heat exchange fluid, a DC voltage refrigeration fluid chiller, measurement sensors, battery, voltage converter and a microprocessor packaged in a hard case with wheels and handle for patient portability.

Cosmetic method and apparatus are provided that can provide cooling and/or freezing of skin tissue proximal to the skin surface to generate an appearance of lightening or reduced pigmentation in the skin. The skin can be cooled to a temperature of less than about −5 degrees Celsius for a duration of about one minute or less, using a plurality of cooled contact surfaces, each having a width between about 2 mm and about 20 mm. A cooling arrangement can be provided to provide controlled heat removal from the skin tissue being treated. A sensor can optionally be provided to detect freezing of tissue proximal to the cooled surfaces.

Disclosed are methods of obtaining zero vergence ultrasound waves for providing sonodynamic therapy with ultrasound waves that do not converge and do not diverge. The method includes coupling a sonodynamic therapy device with an array of flat piezoelectric transducers to a skin surface. A controller is configured to generate an electrical drive signal at a frequency, modulate the drive signal, and drive the transducer with the modulated drive signal at the frequency to produce a zero vergence ultrasound wave to produce an average acoustic intensity sufficient to activate a sonosensitizer in a treatment region without damaging healthy cells in the treatment region.

A temperature regulating socket apparatus for selectively heating or cooling a residual limb of an amputee is provided. The temperature regulating socket apparatus includes a socket having a brim, a distal end and a continuous side wall, all defining an open interior area for receiving the residual limb therein and a temperature regulating apparatus. The temperature regulating apparatus includes a thermal adjustment element embedded within the socket side wall; a temperature control unit operatively coupled to the thermal adjustment element; and a power supply operatively coupled to the temperature control unit. When the power supply is in its ON orientation the temperature control unit is powered so that the temperature control unit regulates the temperature of the thermal adjustment element to selectively heat or cool the residual limb within the socket.

Disclosed herein are systems, pads, and methods thereof for targeted temperature management. A first pad can include a multilayered pad body and an inflatable cuff around the pad body. The pad body can include a conformable layer, a conduit layer over the conformable layer, and an insulation layer over the conduit layer. The conformable layer can include a conformable material configured to conform around a limb of a patient. The conduit layer can include one or more conduits configured to convey a fluid through the conduit layer. The insulation layer can be configured to insulate the conduit layer from an ambient temperature of an environment around the patient. The inflatable cuff can be configured to press the pad body against the limb of the patient when the inflatable cuff is inflated. Methods of the systems and pads can include methods of use.

Disclosed herein are systems, pads, and methods thereof for targeted temperature management. In an example, a pad for targeted temperature management can include a pad body, a conduit system, one or more inlets, and one or more outlets. The pad body can be of a conformable material configured to conform to a body of a patient on the pad. The conduit system can be disposed in the pad body or an overlayer configured for placement over the pad body. The conduit system can include one or more conduits configured to convey a fluid through the pad body or the overlayer. The one-or-more inlets can be configured for charging the conduit system with the fluid, while the one-or-more outlets can be configured for discharging the fluid from the conduit system. Methods of the systems and pads can include methods of use. In another example, a deformable pad can be configured for receiving a neonatal patient.