A protective dressing includes an outer dressing and an adhesive layer. The outer dressing includes an opening and a cavity sized to receive a phase-change material (PCM) insert inserted through the opening. The adhesive layer is configured to adhere to a patient's skin surrounding an anatomic site. When adhered to the patient's skin, the PCM insert modifies the patient's skin at the anatomic site. The PCM insert may be removed and replaced with another PCM insert. For example, a warm PCM insert may be replaced with a refrigerated PCM insert. The opening of the outer dressing may be self-sealing. The opening of the outer dressing may be sealed with an upper layer dressing coupled to the PCM cooling insert.

Personal thermal stability control herein provides for personalized temperature regulation dependent upon biometric sensor feedback, sleep stage, and so on, particularly for sleeping users, predicting and preemptively responding to fluctuations indicative of thermal stability, resulting from such things as transitions between sleep stages, hot flashes, night sweats, and general thermal instability. Specifically, in one embodiment, a system herein may comprise: an on-demand cooling system; one or more biometric sensors configured to monitor one or more corresponding indicators of thermal stability of a user; and a controller configured to: a) receive the one or more corresponding indicators of thermal stability of the user; b) predict an onset of a thermal instability of the user based on the one or more corresponding indicators of thermal stability of the user; and c) activate the on-demand cooling system to counteract the predicted onset of a thermal instability of the user.

In methods for treating a patient, a time varying magnetic field is applied to a patient's body and causes a muscle contraction. The time-varying magnetic field may be monophasic, biphasic, polyphasic and/or static. The method may reduce adipose tissue, improve metabolism, blood and/or lymph circulation. The method may use combinations of treatments to enhance the visual appearance of the patient.

Methods of treating tumors by administering compounds to a patient are provided. Compounds such as pro drugs, e.g., 5-aminolevulinic acid (5-ALA), may be administered to the patient orally, by injection, intravenously, or topically, which then accumulate preferentially as compounds such as protoporphyrin IX (PpIX) in tumor cells. After such accumulation, compounds such as PpIX are then activated in various aspects to treat tumors cells, thereby treating cancer. Cancers such as glioblastoma may be treated.

A method and system in accordance with a particular embodiments of the technology includes applying a substance onto skin of a human subject. The applied substance can include a freezing point depressant and a liposome, an oil-in-water emulsion, a water-in-oil emulsion, or an oil-in-oil emulsion and can be configured to protect or target tissue. The substance and a surface of the skin can be cooled using the applicator to treat acne and other skin conditions.

A thermal pad system is disclosed in which two or more thermal pads can be connected together to cover a larger region of the body than a single pad, and the joining is done in such a way that there is substantially no gap between the volumes of thermal material in each pad on the side of the pads that is applied to the user's body. Each thermal pad is substantially flat, and includes a fringe portion around a volume of thermal material, wherein the two sides are joined together to create a liquid barrier. A joining clip is used to connect two thermal pads together by lifting the fringe portions along corresponding edges of the two pads away from the side of the pads to be applied to the body, and the joining clip is configured to not just hold the fringe portion sections together, but also to urge the two volume portions together under the joined fringe portion sections.

A heat exchanger is disclosed for causing cryolysis of adipose tissue of a human tongue. The heat exchanger includes a body having cooling channels for circulating fluids therein. The body forms a contact surface that contacts a portion of the dorsal surface of the tongue and a portion of the base of the tongue. The heat exchanger includes a pair of side walls extending from the body and forming a pair of side contact surfaces that are dimensioned so that they contact the dorsal and lateral surfaces of the tongue in a manner so as to constrict the tongue when the contact surface is in contact with the tongue. A method of treatment for apnea using the heat exchanger and/or administering a chemical adipolysis formulation/vasoconstriction agent is also disclosed.

A treatment system includes a generator and a fluid transfer cartridge. The fluid transfer cartridge includes a cartridge shell defining a cartridge cavity between a front face and a rear face. The front face includes an opening, and the cartridge cavity is visibly exposed through the opening. The fluid transfer cartridge includes a syringe barrel disposed within the cartridge cavity, and a handle that extends from the front face over the opening. The syringe barrel can be visibly exposed on a side of the handle. Other embodiments are also described and claimed.

Disclosed herein are systems, methods, and a targeted temperature management (TTM) pad to facilitate thermal energy transfer between TTM fluid and a patient. The TTM pad includes a pad portion for placement on the patient and a fluid delivery conduit. The fluid delivery conduit can include a delivery conduit connector at a proximal end thereof and a fluid return conduit extending away from the pad portion. The fluid return conduit can include a return conduit connector at a proximal end thereof, and a connector coupled to a distal end of each of the fluid delivery conduit and the fluid return conduit. The connector can include a membrane configured to cover openings of both of the fluid delivery conduit and the fluid return conduit or includes multiple membranes, wherein the one or more membranes can include a piercing corresponding to each of the fluid delivery conduit and the fluid return conduit.

Afforded is a medical head-cooling cap set that heightens scalp-cooling efficiency and that fitted on to a user's head produces no pressuring feeling nor slips out of place. The cap set is constituted from a head-cooling cap, an inner cap, and an outer cap. Two first belts that are drawn out from either side of the outer-cap opening part and stretch to the exterior are linkable by a first fastener, and after the head has been passed into the opening and the outer cap has been donned, the belts can be fastened neck-area-forward by the fastener; meanwhile, two second belts that extend from alongside the rear part mid-brim and head front brim-ward are linkable by a second clasp, and after the head has been passed into the opening and the outer cap has been donned, the second belts can be fastened around the forehead by the clasp.