A method and system in accordance with a particular embodiments of the technology includes applying a substance onto skin of a human subject. An applicator is then applied to the subject to cool a region of the subject. After cooling the tissue, a nucleation initiator is used to initiate a freeze event in the tissue. The nucleation initiator can be an ice crystal that inoculates the skin upon contact to create a predictable freeze event therein. The time of contact between the ice crystal and the skin can be controlled to achieve desired effects.

An apparatus and method for providing heat exchange in the lungs of the mammal during partial liquid ventilation are provided. The apparatus and method can control delivery and removal of partial liquid ventilation to the lungs of a mammal by responding to pressure change in the lungs to minimize danger of causing barotrauma to the patient.

A neck fan includes an arc-shaped shell configured to hang around user's neck and at least four fan assemblies arranged in the shell. The shell includes a first part and a second part. Each of the first part and the second part defines an accommodating space, air inlets and air outlets communicated with the accommodating space, at least one partition is arranged in the accommodating space and configured to divide the accommodating space into at least two accommodating parts arranged along an extension direction of the shell. Each of the fan assemblies is arranged in one of the at least two accommodating parts and is configured to direct air into the one of the at least two accommodating parts through corresponding air inlets and to direct air out of the one of the at least two accommodating parts through corresponding air outlets.

Disclosed herein is a method of alleviating symptoms of ocular surface discomfort, the method comprising: topically applying a cold slurry adjacent to a corneal limbus of an eye of a patient, wherein the cold slurry comprises water and a freezing point depressant, wherein the topical application of the cold slurry is configured to cause a degree of numbing of a cornea of the eye for a period of time, and wherein an ocular sensation of the eye is restored following the period of time.

A catheter system for infusing a chilled fluid into a subject can include an input lumen, a return lumen, and a transition lumen that provides sufficient flow resistance to urge a first portion of fluid flowing out of the input lumen in the forward direction to flow into the return lumen in the reverse direction toward a cooling device, while a second portion of the fluid flowing out of the input lumen in the forward direction flows out of the distal end of the catheter and into the subject's blood vessel.

A neck fan includes an arc-shaped shell configured to hang around user's neck and at least four fan assemblies arranged in the shell. The shell includes a first part and a second part. Each of the first part and the second part defines an accommodating space, air inlets and air outlets communicated with the accommodating space, at least one partition is arranged in the accommodating space and configured to divide the accommodating space into at least two accommodating parts arranged along an extension direction of the shell. Each of the fan assemblies is arranged in one of the at least two accommodating parts and is configured to direct air into the one of the at least two accommodating parts through corresponding air inlets and to direct air out of the one of the at least two accommodating parts through corresponding air outlets.

A directable, portable appliance in combination with an adjustable set-point digital temperature controller for non-contact remotely monitoring infrared temperatures of a selected area of human skin and activating an electrical fan for directing cooling air over the selected skin areas of individuals experiencing episodes of thermal chaos, i.e., hot flashes.

Disclosed herein is a method of alleviating symptoms of ocular surface discomfort, the method comprising: topically applying a cold slurry adjacent to a corneal limbus of an eye of a patient, wherein the cold slurry comprises water and a freezing point depressant, wherein the topical application of the cold slurry is configured to cause a degree of numbing of a cornea of the eye for a period of time, and wherein an ocular sensation of the eye is restored following the period of time.

A neck fan includes an arc-shaped housing configured to hang around user's neck and at least four fan assemblies arranged in the housing. The housing includes a first part and a second part. Each of the first part and the second part defines an accommodating space, air inlets and air outlets communicated with the accommodating space, at least one partition is arranged in the accommodating space and configured to divide the accommodating space into at least two accommodating parts arranged along an extension direction of the housing. Each of the fan assemblies is arranged in one of the at least two accommodating parts and is configured to direct air into the one of the at least two accommodating parts through corresponding air inlets and to direct air out of the one of the at least two accommodating parts through corresponding air outlets.

The present invention generally relates to improved medical devices, systems, and methods, with exemplary embodiments providing improved cooling treatment probes and cooling treatment methods and systems. In some embodiments, freezing of the skin may be desirable to effect the hypopigmentation of the skin of the patient. Generally, embodiments may limit supercooling of the skin of the patient during a cooling treatment. Additionally, embodiments may limit adverse side effects such as hyperpigmentation. It has been found that the freezing behavior (frequency and time to freeze) can be modified by adjusting the thermal parameters of the cooling applicator. Accordingly, in some aspects of the invention, a method of treating the skin may be provided where the thermal parameters of the cooling applicator are adjusted during treatment.