Described are methods for inducing browning of adipose tissue. More specifically, the present disclosure relates generally to methods for inducing browning of adipose tissue remote to the treatment location. The methods can include at least a first treatment and a second treatment, wherein the treatments comprise applying a cooling element to a local adipose tissue deposit, wherein the cooling element cools the local adipose tissue deposit to a temperature of between 0° C. to 30° C. for a period of time sufficient to induce browning of adipose tissue in one or more areas of the subject's body remote to the local adipose tissue deposit.

A method and apparatus are disclosed for preventing injury to an esophagus caused by heat or cold being delivered to the left atrium, the method including altering a heat exchange device from an insertable configuration to a heat exchanging configuration which has an inflated generally flattened cross section (e.g. capsule-shaped, elliptical) corresponding with the cross section of the inside of the esophagus such that the esophagus is maintained in its natural shape and location. In some embodiments the heat exchange device has a heat exchanger which is inflated to be in the heat exchanging configuration.

According to some embodiments, a method of treating a skin surface of a subject comprises heating a skin surface, abrading native skin tissue of a subject using a microdermabrasion device, wherein using the microdermabrasion device comprises moving the microdermabrasion device relative to the skin surface while simultaneously delivering at least one treatment fluid to the skin surface being treated and cooling the abraded skin surface.

A cooling attachment module for use with a vibration therapy device that includes a housing and/or heat sink member that includes inner and outer walls and defines a central opening axially therethrough. A cooling recess is defined in an upper surface and a connection recess is defined in a lower surface of the heat sink member. A cover member is secured over the cooling recess. A controllable temperature element is positioned on an upper surface of the heat sink member. A spreader member is positioned on an upper surface of the controllable temperature element. An upper surface of the spreader member is positioned above an upper surface of the cover member to contact a user's body part. The controllable temperature element is configured to transfer thermal energy to a lower surface of the spreader member. A base portion that includes an electrical connector is secured under the electrical recess.

Methods, devices, and systems employ cryolysis of oropharyngeal adipose tissues to selectively remove fat cells from the tissues causing obstructive sleep apnea. In various embodiments, a chilled liquid—e.g., a liquid or air—is applied to the target tissue at a temperature and for a duration sufficient to cause cryolysis.

The present invention relates to a mask-shaped skin treatment device and system. The device comprises one or more coupling agent detectors configured to detect presence of coupling agent on one or more skin portions of a user and one or more heating elements configured to cause local heating of one or more skin portions of the user. The one or more heating elements are configured to cause heat selectively based on the presence of coupling agent measured by the one or more coupling agent detectors.

An eye compress assembly includes two thermally adjustable heating and cooling device and a bridge connecting the two devices is provided. The thermally adjustable device is configured to apply thermal treatment against the eye region. Within the thermally adjustable heating and cooling device the thermoelectric element is powered by a battery. A power input port is provided in the bridge to connect into a power supply in order to recharge the battery.

Thermal management systems including a thermoelectric component, a two-phase heat transfer unit, and a controller are disclosed herein. The heat transfer unit has a phase-transition chamber and microfeatures in the phase-transition chamber that induce capillary forces to a working fluid that drives the working fluid through the phase-transition chamber. The controller is configured to operate the thermoelectric component and the heat transfer unit such that the heat transfer unit cools one side of the thermoelectric component to a first temperature and the thermoelectric component changes the temperature of a target material on its other side to a second temperature of +/−60° C. of the first temperature within 0.5-20 seconds.

Wearable heat transfer devices and associated systems and methods are disclosed herein. In some embodiments, a representative heat transfer device can comprise (i) thermoelectric components each having a first side and a second side, (ii) a heat transfer system having a heat exchanger and an array of fluid distribution networks, in which individual fluid distribution networks are thermally coupled to the second side of a corresponding one of the thermoelectric components and fluidically coupled to the heat exchanger, and (iii) a flexible support unit coupled to the first sides of the thermoelectric components and extending at least between individual thermoelectric components, wherein the flexible support unit is a heat spreader configured to enhance heat transfer from a target area.

This document describes implantable medical device systems and methods of using such devices for delivering therapy via temperature modulation. For example, this document describes medical device systems and related methods for the treatment of cardiac arrhythmias by delivering cooling to epicardial tissue. In some embodiments described herein, arrhythmias can be treated by an implantable system for painlessly terminating arrhythmias. The devices and methods provided herein permit prompt termination of atrial fibrillation almost immediately after an episode begins (to prevent persistence) and are effective irrespective of patient age and comorbidities.