A pain-reducing injection apparatus to enhance the safety, efficacy, and efficiency of injection procedures which utilize topical pain-reducing measures. Apparatuses and methods of use provide pain reduction through thermal cooling of an injection region or vibrating the region or both, and optionally include safety shielding and lockout features.

Disclosed herein is a system, apparatus and method directed to patient temperature control. The system can include a control module configured to provide fluid that is heated or cooled, a heating and cooling system configured to couple with the control module and receive the fluid, and a temperature sensor coupled to the control module, the temperature sensor configured to measure a body temperature of a patient and provide signals to the control module that indicate the body temperature. The system can include a neurostimulation device coupled to the control module to provide neurostimulation to the patient. The control module can include logic, stored on non-transitory, computer-readable medium that, when executed by one or more processors, causes performance of operations including generation and transmission of first instructions to the neurostimulation device causing initiation of a first neurostimulation procedure.

Disclosed herein is a patient interface for wound treatment and/or management, comprising: an interface body configurable to substantially or at least partially surround a wound, the interface body comprising a gas inlet and defining a first gas flow path having a first flow resistance, and a second gas flow path having a second flow resistance. The first gas flow path is arranged in fluid communication with the gas inlet and the second gas flow path. The interface body comprises or is configurable to provide a gas outlet at or adjacent to the wound site.

A hand-held or wearable device for cooling tissue of an eye of a patient is disclosed. In one aspect, the device includes a reservoir having fluid therein and a support connected to the reservoir and configured to be positioned on a face of the patient. The device also includes a nozzle positioned proximate to the support and fluidically connected to the reservoir, the nozzle configured to pass the fluid from the reservoir onto a surface of the eye. The device further includes a cooling element configured to cool the fluid from the reservoir such that it exits the nozzle at a temperature of between −100° C. and 15° C. The device further includes an ultrasonic vibrator positioned near the nozzle and configured to generate mist from at least part of the fluid.

A prosthetic socket cooling system and method includes a strap for coupling about a limb fitted with a prosthetic socket. One or more thermally conductive heat spreaders are associated with the strap and may be at least partially seated underneath the prosthetic socket. A heat extraction subsystem is coupled to at least one of the lengthy heat spreaders and carried by the strap. In one version, heat spreaders may form sections of the strap.

A low-frequency treatment device and a treatment system with enhanced user convenience. An acquisition unit acquires an atmospheric pressure of a position where the low-frequency treatment device is located (step S102), a determination unit determines whether the atmospheric pressure is less than a threshold (step S104), and a treatment portion increases an intensity of low frequency treatment if the atmospheric pressure is less than the threshold (step S108).

Disclosed are methods of obtaining zero vergence ultrasound waves for providing sonodynamic therapy with ultrasound waves that do not converge and do not diverge. The method includes coupling a sonodynamic therapy device with an array of flat piezoelectric transducers to a skin surface. A controller is configured to generate an electrical drive signal at a frequency, modulate the drive signal, and drive the transducer with the modulated drive signal at the frequency to produce a zero vergence ultrasound wave to produce an average acoustic intensity sufficient to activate a sonosensitizer in a treatment region without damaging healthy cells in the treatment region.

An article configured to warm and monitor a patient during a dialysis treatment, the article includes one or more heating elements. The article also includes one or more sensors configured to monitor a condition of the patient during the dialysis treatment. The article also includes a fabric portion configured to receive the one or more heating elements and the one or more sensors and position the one or more heating elements and the one or more sensors on the patient during treatment. The article also includes a transmitter configured to transmit information from the one or more sensors to a dialysis machine and an electrical connector configured to provide power to at least one of the one or more heating elements and the one or more sensors.

The invention relates to an electrical active assembly for generating a physical effect such as heat, cold or humidity, and a textile assembly, such as a clothing assembly, including said electrical active assembly, with an application to a system for regulating the temperature or humidity of a user's body.

The electrical assembly comprises a first textile support, a first active element 1 for generating the physical effect, connected to a power source, and located on or in the first textile support, a first sensor 2 for sensing data relative to a physical information, such as temperature or humidity, connected to a power source, and located on or in the first textile support, and a first controlling unit 3 connected to the first active element and sensor, and located on or in the first textile support, such as to allow the activation/deactivation by the first controlling unit of the first active element depending on data sensed by the first sensor.

The electrical assembly also comprises a second textile support distinct from the first textile support, a second active element 4 for generating said physical effect, connected to a power source, and located on or in the second textile support, a second sensor 5 for sensing data relative to the physical information, connected to a power source, and located on or in the second textile support, and a second controlling unit 6 connected to the second active element and sensor, and located on or in said second textile support, such as to allow the activation/deactivation by the second controlling unit of the second active element depending on data sensed by the second sensor.

The first controlling unit is connected to the second active element and sensor, such as to allow the activation/deactivation by the first controlling unit of the second active element depending on data sensed by the second sensor and/or by the first sensor, and/or the second controlling unit is connected to the first active element and sensor, such as to allow the activation/deactivation by the second controlling unit of the first active element depending on data sensed by the first sensor and/or by the second sensor.

The present invention provides a device for rejuvenating a region of skin or mucosal tissue, comprising: a pulsed electromagnetic frequency generator; a plurality of electrodes in communication with the pulsed electromagnetic frequency generator and an RF tissue diathermy device. The electrodes apply the pulsed electromagnetic power and the RF tissue diathermy to the tissue, heating it such that one portion of the region of mucosal tissue is maintained at a predetermined temperature range T.sub.1 while another portion of the region of mucosal tissue is at least temporarily maintained at predetermined temperature range T.sub.2.