A thermal control unit supplies temperature controlled fluid to a patient to control the patient's temperature. The thermal control unit includes a fluid outlet, fluid inlet, heat exchanger, pump, patient temperature probe port, user interface, and controller. The controller receives patient temperature readings from the patient temperature probe port and controls a temperature of the circulating fluid in a first manner when no event data is received regarding treatment of the patient. The controller controls a temperature of the circulating fluid in a second and different manner when event data is received. The event data may relate to medication and/or fluid administered to the patient. The different manners include determining a target fluid temperature in using different inputs and/or alarming in different manners. In some cases, the controller pauses the use of the patient temperature readings while continuing to deliver temperature controlled fluid to the patient.

Methods, devices, and systems employ cryolysis of oropharyngeal adipose tissues to selectively remove fat cells from the tissues causing obstructive sleep apnea. In various embodiments, a chilled liquid—e.g., a liquid or air—is applied to the target tissue at a temperature and for a duration sufficient to cause cryolysis.

A cryo-system for treating a body part of an individual by cryotherapy, which includes two parts. The first part is either i) a cryo-probe suitable for internal cooling, which includes a penetrating segment in communication with a cryogen source and is at least smaller than 1/10th of the body part's biggest volume and/or at least one dimension smaller than 1 cm or ii) a cryo-probe suitable for external cooling, which includes a non-penetrating segment in communication with a cryogen source. The second part is either i) an assembly of at least two nanoparticles bound to each other or associated with each other via binding or associating material or ii) at least one nanoparticle, which includes iron and at least one other metal than iron. The assembly of at least two nanoparticles or the at least one nanoparticle may be cooled by the cryo-probe or by switching on the cryo-probe.

Methods for treating fluid overload in a subject comprise shifting fluids directly and non-invasively from an interstitial compartment of the subject to skin of the subject through controlled local sweating. Methods of the invention allow for removal of excess fluid from the interstitial compartment of the subject and treat fluid overload in the subject. Sweat stimulation systems comprise a chamber and first and second relative humidity sensors. The chamber is sized to fit around a body part of a subject, comprises an inlet and an outlet, and is configured such that air flows through the chamber from the inlet to the outlet. The first relative humidity sensor is operably located inside the inlet, and the second relative humidity sensor is operably located proximate the outlet.

A fillable palm cooling device is described. The fillable palm cooling device is configured to be filled with a cool substance, and includes at least a first endcap configured to be removed to enable the fillable tube to be filled with the cool substance. The fillable tube is configured to be held in palms of both hands of a person to cool the palms of both hands of the person when the fillable tube is filled with the cool substance.

The present invention relates to a mask-shaped skin treatment device and system. The device comprises one or more coupling agent detectors configured to detect presence of coupling agent on one or more skin portions of a user and one or more heating elements configured to cause local heating of one or more skin portions of the user. The one or more heating elements are configured to cause heat selectively based on the presence of coupling agent measured by the one or more coupling agent detectors.

A medical heating device for heating a person that includes an electronic control unit that is configured as a recyclable module; a flexible heating blanket that is configured to at least partially shield the person from their environment, the flexible heating blanket can be separated from the control unit without destruction, and the flexible heating blanket is configured as a disposable item to permit regular replacement; a heating layer with a carrier layer of a polymeric material and a resistance layer of an electrically conductive material, the heating layer is configured to convert electrical energy into heat, and a plurality of temperature sensors to control the heating layer.

A method of promoting secretion of a growth hormone includes the step of applying a thermal stimulus to specific sites on a body surface of the subject. The step of applying the thermal stimulus includes the steps of placing two or more guide elements made of two different kinds of metals respectively on at least two different sites of the specific sites, and controlling a temperature of the guide elements to be a range from 40 to 50±5° C., thereby applying the thermal stimulus to the specific sites according to a thermal stimulus pattern so as to increase a rate of blood flow in the subject by 60% or more by the application of thermal stimulus.

Wearable heat transfer devices and associated systems and methods are disclosed herein. In some embodiments, a representative heat transfer device can comprise (i) thermoelectric components each having a first side and a second side, (ii) a heat transfer system having a heat exchanger and an array of fluid distribution networks, in which individual fluid distribution networks are thermally coupled to the second side of a corresponding one of the thermoelectric components and fluidically coupled to the heat exchanger, and (iii) a flexible support unit coupled to the first sides of the thermoelectric components and extending at least between individual thermoelectric components, wherein the flexible support unit is a heat spreader configured to enhance heat transfer from a target area.

The invention relates to a device for hyperthermic treatment of itching, for example following insect bites, wherein during the treatment a treatment surface is regulated at a temperature of preferably between 42° C. and 56° C. for a period of 2 sec to 12 sec and a hardware-implemented temperature monitor limits the maximum temperature of the treatment surface and a safety fuse shuts off the device in the case of a short-circuit or uncontrolled continuous heating.