Embodiments include a cryogenic device for alleviating pain by cryogenically treating a nerve, the cryogenic device including a handpiece; a needle coupled to a distal end of the handpiece, the needle including a needle lumen, the needle being configured for insertion into a skin of a patient along an insertion axis at a site laterally displaced from a treatment zone proximate to the nerve. The needle is configured to resiliently bend after insertion away from the insertion axis, such that at least a portion of the needle is adapted to traverse a skin layer laterally toward the treatment zone. The device includes a cooling fluid supply tube extending distally into the needle lumen; and a cooling fluid source, wherein the cooling fluid source is coupled to the cooling fluid supply tube to direct cooling fluid into the needle lumen.

Embodiments of the present disclosure may include an apparel device, including an apparel body including an outer layer and an inner layer, and an interior configured to receive a body part of a user. Embodiments may also include a heat transfer panel disposed between the outer layer and the inner layer. In some embodiments, the heat transfer panel includes a first side and a second side, the first side disposed adjacent the interior of the apparel body. Embodiments may also include a compressed fluid source in fluid communication with the second side of the heat transfer panel. In some embodiments, the compressed fluid source may be configured to selectively deliver compressed fluid to the heat transfer panel. In some embodiments, the heat transfer panel may be configured to cool the interior of the apparel body upon delivery of the compressed fluid to the heat transfer panel.

The present invention provides a device for rejuvenating a region of skin or mucosal tissue, comprising: a pulsed electromagnetic frequency generator; a plurality of electrodes in communication with the pulsed electromagnetic frequency generator and an RF tissue diathermy device. The electrodes apply the pulsed electromagnetic power and the RF tissue diathermy to the tissue, heating it such that one portion of the region of mucosal tissue is maintained at a predetermined temperature range T.sub.1 while another portion of the region of mucosal tissue is at least temporarily maintained at predetermined temperature range T.sub.2.

An electric heating pad for warming a patient. The electric heating pad may be a heated underbody support, heated mattress or heated mattress overlay. An embodiment of the heating pad includes a flexible sheet-like heating element including an upper edge, a lower edge, and at least two side edges. The heating pad may also include a shell covering the heating element and comprising at least two sheets of flexible material (e.g., two sheets may be one sheet folded over to form at least two sheets). The two sheets of flexible material may be coupled together about the edges of the heating element by a weld. The material of the two sheets may include urethane. In some embodiments, a catalyst to accelerate hydrogen peroxide decomposition is coated on or impregnated into an element within the shell, or on the interior surface of the shell.

A flexible catheter is inserted into the esophagus to cool or warm the esophagus, particularly during certain procedures which can tend to change the temperature in the area of the esophagus. The catheter is inserted through the mouth and throat to a position, for example, proximate the heart, but within the esophagus. One or more balloons are inflated to block areas of the esophagus, while a gel is injected into the esophagus where it is immobilized by the one or more balloons. A coolant is pumped through a coolant tube affixed to the catheter, where it exchanges heat with the conductive gel.

A heat exchanger is disclosed for causing cryolysis of adipose tissue of a human tongue. The heat exchanger includes a body having cooling channels for circulating fluids therein. The body forms a contact surface that contacts a portion of the dorsal surface of the tongue and a portion of the base of the tongue. The heat exchanger includes a pair of side walls extending from the body and forming a pair of side contact surfaces that are dimensioned so that they contact the dorsal and lateral surfaces of the tongue in a manner so as to constrict the tongue when the contact surface is in contact with the tongue. A method of treatment for apnea using the heat exchanger and/or administering a chemical adipolysis formulation/vasoconstriction agent is also disclosed.

An apparatus and method use a catheter for specific and discriminate treatment of central nervous system disease. With the catheter, selective hypothermia to the brain and/or the spinal cord for injury protection can be achieved without the need for systemic cooling. The catheter is also capable of draining excess cerebrospinal fluid.

An electric heating pad for warming a patient includes a heated underbody support or heated mattress. The heated underbody support or mattress includes a heater assembly having a flexible sheet-like heating element, conductive bus bars attached at or near side edges of the heating element, and fabric side edge extensions attached to heating element side edges. The heated underbody support or mattress also includes a layer of polymeric foam positioned under the heater assembly and a shell, including at least two sheets of flexible material, covering at least a portion of the heater assembly and the layer of polymeric foam. When the heater assembly is wrapped around the top surface of the layer of polymeric foam, side edges of the heating element extend partially down the two side walls of the layer of polymeric foam and the conductive bus bars lie adjacent those two side walls.

A device for indirect temperature regulation of the brain of a human via a nasal cavity thereof, the device comprising: a membrane having a membrane surface area, a length, a center point with respect to the length, a width, and a center point with respect to the width, said membrane adapted to be arranged in contact with a surface of the nasal cavity, said membrane defining a closed volume and having the shape of the nasal cavity such that when in use, it expands and conforms to the nasal cavity, a first catheter, a second catheter, and means for circulating said fluid into said volume via said first catheter and out of said volume via said second catheter.

A cryogenic fluid composition may include water (H20), and at least one salt. The ratio of water to the at least one salt is approximately between 1% and 6% salt with the remainder water. A cryogenic fluid production device may include a cylindrical housing, and a heat exchanger disposed within the cylindrical housing. The heat exchanger may include an inlet, a channel, and an outlet. A coolant may be conveyed through the inlet, the channel, and the outlet of the heat exchanger. The cryogenic fluid production device may further include an interior wall, and an auger disposed within the interior wall of the heat exchanger.