Devices, systems and methods for controlling the temperature of all or part of the body of a human or animal subject.

A method of treating a subject in need thereof, is carried out by (a) administering said subject a therapeutic intervention (e.g., an active agent) in a treatment effective amount; and concurrently (b) administering said subject caloric vestibular stimulation in a treatment effective amount, said caloric vestibular stimulation administered so as to enhance the efficacy of said active agent. In some embodiments, the caloric vestibular stimulation is administered as an actively controlled time varying waveform.

A device for cooling locally, including a cooling member, a crystal having the capacity to cool via absorption of a near-infrared exciting light signal, an illuminating system intended to deliver an exciting light signal, the crystal having an elongate shape about a longitudinal axis between a near end and a far end and having a closed constant outside cross section and containing a central channel formed, from its far end, over at least some of its length, the cooling member including a rod embedded via a first end into the central channel of the crystal and including a protruding second end that forms a cooling finger.

A rapid contrast therapy system can provide cold, heat/hot/warm (hereafter referred to as “hot”), and/or rapid contrast therapy, which involves rapidly alternating between cold therapy and hot therapy. The system can circulate cold or hot fluid, such as water, through a hose, into a therapy wrap, and then back to the fluid reservoirs of the system. The system can utilize a vapor compression system or other chiller technology to cool the cold water reservoir, and immersion heaters can be used to heat the hot water reservoir.

Devices, systems and methods for removing heat from subcutaneously disposed lipid-rich cells are disclosed. In selected embodiments, suction and/or heat removal sources are coupled to an applicator. The applicator includes a flexible portion and a rigid portion. The rigid portion includes a thermally conductive plate and a frame coupling the thermally conductive plate and the flexible portion. An interior cavity of the applicator is in fluid communication with the suction source, and the frame maintains contiguous engagement between the heat removal source and the thermally conductive plate.

Provided herein are systems, devices and methods for the treatment of fungus. In particular, provided herein are systems, devices and methods employing energy to nail and tissue structures to treat fungal infection.

A thermal accessory controller for controlling the temperature of a thermal accessory. The thermal accessory controller includes a liquid reservoir for storing a glycol-based liquid, a heating component in liquid communication with the liquid reservoir for heating the glycol-based liquid, and a cooling component for cooling the glycol-based liquid. The thermal accessory controller includes an input conduit that provides a liquid path for the glycol-based liquid from the thermal accessory controller to the thermal accessory and an output conduit that provides a liquid path for the glycol-based liquid from the thermal accessory to the thermal accessory controller. The thermal accessory controller also includes a first liquid pump in liquid communication with the input conduit and the output conduit and configured to pump the glycol-based liquid through the thermal accessory, the liquid reservoir, and the heating component.

Embodiments related to methods and wearable medical detecting systems for detecting disease states and/or treatment states of a subject are described. In one embodiment, a wearable structure may include one or more radiation detectors use to detect a time varying radiation signal emitted from a labeled compound within a body portion of interest. The radiation signal may be analyzed to determine one or more signal characteristics that may be compared to one or more predetermined standard characteristics associated with known disease and/or treatment states to determine a current disease and/or treatment state of a subject.

A temperature therapy system and a method for temperature control for such a temperature therapy system are disclosed. According to one embodiment, a temperature therapy system has a retention mechanism and a plurality of temperature modulation systems attached to the retention mechanism, wherein each of the plurality of temperature modulation systems comprises a thermoelectric cooler. The wearable personal temperature therapy system may have a plurality of temperature sensors and a plurality of conductive flags, wherein each of the plurality of conductive flags is adhered to a respective thermoelectric cooler and a respective temperature sensor. The wearable personal temperature therapy system may have a control module electrically coupled to each of the plurality of temperature modulation systems and each of the plurality of temperature sensors, wherein each of the temperature modulation systems is controlled based on a control voltage applied to the thermoelectric cooler of the respective temperature modulation system.

A personal heating and cooling system comprising a chair, a pad comprising a length of flexible tubing and at least one heating element housed in an interior area of the pad, a pump configured to pump a volume of coolant (e.g., water) through the length of the flexible tubing, an intake trunk coupled to the pump and configured to deliver a volume of water from a reservoir (e.g., from a thermal insulated cooler) and a battery pack operably engaged with the pump and the at least one heating element. In certain embodiments, the pad may be integral to the chair and comprise seat and back portions of the chair. In certain embodiments, the pad may be removably coupled to the chair or other seating surface or may be laid flat.