The preparation and use of fluorescent cell markers of the structure F-S.sub.1-S.sub.2-L is described where F is a fluorophore, S.sub.1-S.sub.2 is a spacer linking F to L, and L is a diacyl lipid.

The present invention relates to new fluorescent markers selectively binding tau protein, uses thereof, methods for imaging the neurofibrillary tangles of the tau protein in the retina of a subject, as well as a device that enables the implementation of said methods.

An optical film includes: a transparent substrate; and a colored layer laminated on at least one side of the transparent substrate, the colored layer containing a dye (A), the dye (A) containing a colorant having a wavelength of maximum absorption in the range of 470 nm to 530 nm, the colorant containing a dipyrromethene cobalt complex having a structure represented by formula (I), in which R.sup.1 to R.sup.7 are combined such that a free energy change between before and after the reaction, calculated by applying R.sup.1 to R.sup.7 in the formula (I) to a predetermined reaction formula (II) using a quantum chemical calculation program Gaussian 16 with a calculation method B3LYP and a basis function 6-31G (d,p) (however, a basis function LanL2DZ is assigned to elements having an atomic number greater than that of Kr in the periodic table), is 0.92 kcal/mol or greater.

A light emitting element includes a first electrode, a second electrode on the first electrode, and an emission layer between the first electrode and the second electrode and including a first compound represented by Formula 1.

##STR00001##

Described herein are devices, compositions, and methods for improving color discernment.

[Problem] To provide the following: a novel fluorescent probe for detecting a compound, such as glutathione, that contains a SH group; a detection method using said fluorescent probe; and a detection kit containing said probe.

[Solution] A fluorescent probe for detecting a compound containing an SH group, wherein the fluorescent probe comprises a compound represented by formula (I) or a salt thereof (In the formula, X represents Si(Ra)(R.sup.b), Ge(R.sup.a)(R.sup.b), Sn(R.sup.a)(R.sup.b), C(R.sup.a)(R.sup.b), or O (wherein R.sup.a and R.sup.b each independently represent a hydrogen atom or alkyl group); R.sup.1 represents a hydrogen atom, or 1-4 identical or different substituents independently selected from the group consisting of a cyano group, alkyl group, carboxyl group, ester group, alkoxy group, amide group, and azide group, each of which may be optionally substituted; R.sup.2 represents a hydrogen atom, halogen atom, hydroxyl group, cyano group, or an alkyl group, alkynyl group, alkoxy group, aryl, or heteroaryl, each of which may be optionally substituted; R.sup.3 and R.sup.4 each independently represent a hydrogen atom or 1-3 identical or different substituents independently selected from the group consisting of a hydroxyl group, halogen atom, or an alkyl group, sulfo group, carboxyl group, ester group, amide group and azide group, each of which may be optionally substituted; R.sup.5, R.sup.6, R.sup.7 and R.sup.8 each independently represent a hydrogen atom or alkyl group, wherein, R.sup.5 or R.sup.6, respectively together with R.sup.3, may form a ring structure including the nitrogen atoms bonded thereto, or R.sup.7 or R.sup.8, respectively together with R.sup.4, may form a ring structure including the nitrogen atoms bonded thereto).

Platinum complexes that exhibit photoabsorption and photoemission, methods of making such complexes, and applications thereof are disclosed, including optical devices comprising the complexes.

Compounds comprising phosphorescent metal complexes comprising cyclometallated imidazo[1,2-f]phenanthridine and diimidazo[1,2-a:1,2-c]quinazoline ligands, or isoelectronic or benzannulated analogs thereof, are described. Organic light emitting diode devices comprising these compounds are also described.

Platinum, palladium, and gold complexes suitable for use as phosphorescent emitters or as delayed fluorescent and phosphorescent emitters in organic light emitting materials (OLEDs) having a structure of Formula VII or Formula IX ##STR00001##

Disclosed are a linear boron-dipyrromethene electron donor having a 180 coordination included angle and a supramolecular metallacycle, and synthesis processes therefor and applications thereof. The invention provides a linear boron-dipyrromethene electron donor as shown in formula 3 or formula 4, and a boron-dipyrromethene ligand-based supramolecular coordination compound having a 180 coordination included angle which is prepared by the metal coordination of the linear boron-dipyrromethene electron donor. Compared with a prepolymer, the boron-dipyrromethene ligand-based supramolecular coordination compound has better cell passive uptake capacity, cell fluorescence imaging capacity and photosensitive (singlet oxygen generation) capability.