A patient interface device for use in ophthalmic surgery, which includes a rigid body and a suction ring joined to a lower end of the body, where the suction ring includes an annular skirt made of a soft and flexible material and located at a lower end of the suction ring, and where an inner surface, and optionally an outer surface, of the skirt is coated with medication. The medication includes one or more of the following types of medication: anti-inflammatory, antibiotic, numbing, lubricating, and anti-redness. The coating method may include dip coating, sputter deposition, ultrasonic-spraying, and spin-coating. The skirt may be formed by a process that increases its material porosity and/or surface roughness, and may be surface-treated to enhance adhesion and retention of the medication.

A device for dispensing a mist of an ophthalmic fluid includes a discharge opening for said mist, a mixing chamber communicating with said discharge opening, an air chamber holding a volume of air, a first drive operable to expel air from said air chamber, a fluid chamber for holding a volume of the fluid to be dispensed and communicating with said mixing chamber, a second drive for delivering a predetermined dose of said fluid to said fluid chamber, said air chamber communicating with said fluid chamber and with said mixing chamber, said device establishing one flow of expelled air flowing into said fluid chamber, so as to force liquid from said fluid chamber into said mixing chamber, and another flow of said expelled air flowing past said fluid chamber into said mixing chamber.

An ocular implant system including an ocular implant sized and shaped to be inserted at least partially into an eye; a carrier member with a shell having a central channel extending at least partially through the shell from a proximal end towards a distal end of the shell. A guide sleeve removably attached within at least a first region of the central channel of the shell and defining a proximal port into the central channel that is accessible from the proximal end of the shell. An implant holder removably attached within at least a second region of the central channel of the shell adjacent to a distal end of the guide sleeve and having a pair of graspers adapted to releasably secure the implant at a distal end of the implant holder. Related devices, systems, and/or methods are described.

A therapeutic system comprises an ocular insert placed on a region outside an optical zone of an eye. The ocular insert comprises two structures: a first skeletal structure and a second cushioning structure. The first structure functions as a skeletal frame which maintains positioning of the implant along the anterior portion of the eye and provides support to the second, cushioning structure. This first structure maintains the attachment of the therapeutic system to the anterior portion of the eye for at least thirty days. In some embodiments the first structure remains a constant size and shape, e.g. a ring shape, a ring with haptics, or a curvilinear ring that is confined to and restrainingly engages the inferior and superior conjunctival fornices so as to retain the implant within the tear fluid and/or against the tissues of the eye.

A non-invasive ocular drug delivery device can include a housing adapted to couple to an eye of a subject. An active agent matrix can be coupled to the housing. The active agent matrix can include an electro spun material having a combination of a density, a thickness, and an ocular surface area configured to hold and retain an active agent prior to application of the device to the eye, and deliver an effective dose of an active agent within 30 minutes of application of the device to the eye.

A method of treating a subject with an ocular condition responsive to steroid therapy can include administering a threshold dose of a steroid to an eye of the subject in a therapeutically effective regimen that minimizes an intraocular pressure (IOP) increase above a baseline level.

Various systems and techniques may be used for moisturizing an eye during ocular surgery. In particular implementations, a system and a technique for moisturizing an eye may include the ability to determine whether an eye should be moisturized during ocular surgery and to activate a fluid control device if an eye should be moisturized. The activation of the fluid control device may allow fluid flow from a fluid reservoir to a fluid nozzle coupled to a nozzle mounting device adapted to hold the fluid nozzle stable relative to a patient's eye. The system and the technique may also include the ability to deactivate the fluid control device.

Several embodiments disclosed herein relate to the delivery of therapeutic nucleic acids to an ocular tissue in order to provide a therapeutic effect to reduce symptoms of or otherwise alleviate an ocular disorder. In particular embodiments, plasmid DNA is delivered to the cells of the trabecular meshwork in order to ameliorate increasing intraocular pressure. Devices and systems to accomplish this delivery are also disclosed.

The present invention is a device that is used in squint surgeries which contains two parts: the first part is fixated to the insertion and the second part is fixated to the muscle/muscle tendon, and the two parts are connected to each other with two threads at both sides, in this device the distance between the two parts can be adjusted; hence the magnitude of muscle resection or recession. Also a new procedure (alternative to resection procedure) is provided; in which we shorten the muscle without resecting it. In addition to the main device, there is a tiny sclera screws that can fixate any device implanted on the sclera.

The present disclosure provides methods and apparatus for administration of ophthalmic treatments into a patient's eye. Apparatus may include a wire form with a horizontal upper frame, temples that rest on or hook over the ears, nose pads, and semi-circular receivers to accept the tip of an eye drop-dispenser bottle. In some examples, distance sensing apparatus and signaling capabilities may be present to support the administration of ophthalmic treatments. In some examples, the apparatus may be enhanced for the purposes of aiding the application of eyedrops by a deep upper horizontal frame that rests on the forehead to prevent the apparatus, and thereby the eye dropper bottle, from approaching the eye too closely.