An ocular implant including a drug releasing element and having an inlet portion and a Schlemm's canal portion distal to the inlet portion, the inlet portion being disposed at a proximal end of the implant and sized and configured to be placed within an anterior chamber of a human eye, the Schlemm's canal portion being arranged and configured to be disposed within Schlemm's canal of the eye when the inlet portion is disposed in the anterior chamber.

The present invention relates to a method for topical administration of ophthalmic compositions in a dropwise manner, preferably for topical administration of ophthalmic compositions comprising semifluorinated alkanes (SFAs). Further, the present invention relates to the use of said methods in the prevention or treatment of ocular diseases or disorders or any symptoms or conditions associated therewith. In a further aspect, the present invention relates to a kit comprising a drop dispenser at least partially filled with a liquid composition for the use in such a method and directions for use of said drop dispenser.

In various embodiments, a drug pump includes a housing and, within the housing, an expandable drug reservoir at least part of which is exposed to a pressurized propellant. The propellant exerts a substantially constant pressure on the drug reservoir. A flow restrictor significantly limits outflow from the pump, and preferably has both a small diameter and a long path length, which acts to control the outflow from the drug reservoir. As a result, the pump produces a substantially constant outflow.

This invention is a handheld multipurpose device for standardizing intraocular access for injecting into or obtaining substance(s), content(s), medicine(s), or sample(s) from a human eye(s) or an animal eye(s), in any age group(s), once a specific marker(s) is placed at corneal scleral Limbus. The device is comprising an elongated handle connected to a body having a walled structure with no spaces, one or more space(s) at the bottom; a predesigned curvature(s) in the said device to aid in placement on the surface of the eye; a set or more of track(s) with entry and exit port(s) travelling within the wall(s) at a certain angle and length; a groove that outlines the outer walls limited above and below by projections; a needle hub adapter(s) and/or receiver(s) that allows universal attachment of any injecting device(s) with an opening to the bottom of the device; a projecting marker(s) on one or more sides that indicates where the whole device should rest on the eye at the Cornea-Sclera junction called Limbus; a large opening/window at the bottom of the said device allowing access to all structures of the anterior segment of the eye; and a larger opening(s) and/or window(s) allowing a reservoir function, as well as access to posterior segment and a set of repeated projections from the underside of the device to facilitate gripping to the eye tissue underneath.

An injection device and method are shown. Devices and methods include a forceps and a needle advancement mechanism to clamp a portion of tissue and control a depth of penetration of the needle between gripping ends of the forceps. An injection device and method are shown where selected components of the injection device such as a syringe and forceps are disposable, while the remaining portions of the injection device are reusable. Devices and methods are shown that utilize micro-needles to control a depth of penetration.

The present invention includes and provides a method of delivering a medicament to an eye of a subject in need thereof a solution, the method comprising: (a) providing droplets containing the medicament with a specified average size and average initial ejecting velocity; and (b) delivering the medicament to the eye, where the droplets deliver a percentage of the ejected mass of the droplets to the eye.

An ophthalmic laser ablation system is described with various optional features, some especially suitable for non-penetrating filtration on an eye. In one example, focusing of an ablation laser uses a movable lens coupled to a pair of converging light sources, which converge at the focal distance of the lens. In another example, laser ablation settings are selected for optimal ablation and minimal amount of thermal damage of a layer of percolating scleral tissue.

A surgical ophthalmic intra ocular access tool comprising a platform having a walled structure with central space(s), that is placed on the surface of the eye; a set or more of track(s) with entry and exit port(s) travelling within the wall(s) at a certain angle and length; a needle hub receiver(s) that allows universal attachment of any injecting device(s) with an opening to the bottom of the surgical ophthalmic intra ocular access tool; a projecting marker(s) on one or more sides; a set of repeated projections from the underside of the surgical ophthalmic intra ocular access tool to facilitate gripping to the eye tissue underneath; a rail like system outlining the inner as well as the outer walls, allowing multiple accessory(s) to be attached to either rail to facilitate surgical intervention(s) and predesigned holes at lower edge of said surgical ophthalmic intra ocular access tool in contact with eye wall(s) allowing for suturing in order to obtain secure attachment(s) or augmented wall(s) support.

Eye irrigation can be facilitated via an adapter apparatus to connect an IV tube to a nasal cannula. The adapter apparatus can be constructed to provide a fluid transfer between the IV tube and the nasal cannula. Additionally, a modified nose clip can perform the function of facilitating fluid transfer from an IV bag to the eyes of a patient during an eye irrigation procedure.

An applicator for applying fluid medicaments to a corneal surface of a patient, after surgery, includes a circular, ring-shaped member. The ring member creates an aperture which extends between parallel planes, with a wall surrounding the aperture as well as upper and lower openings into the aperture. The wall around the aperture is tapered, and there is a hole that extends through the wall. A hollow shaft is connected in fluid communication with the hole in the wall through which a fluid can be injected into the aperture. A bubble of the fluid can then be cradled in the aperture by the wall, and held therein by surface tension across the lower opening of the aperture.

An application of the fluid bubble onto the patient's eye requires only contact between the fluid bubble and the eye, with no need for contact between the applicator and the eye.