An eye drop assist apparatus and method for sequentially administering an ocular medication into a patient's eyes. A bottle or vial containing liquid eye drops is supported in a holder. First and second nasal locators extend in opposite directions from the holder. The nasal locators are separated by the pupillary distance (typically 60 mm), with the dispensing tip of the bottle located mid-way between. A person administering eye drops abuts the first nasal locator against the top of the patient's nasal bridge while aligning the tip of the bottle directly over a first eye before squeezing the bottle to forcibly expel one or more drops into the first eye. The person then linearly translates the bottle so that the second nasal locator abuts against the top of the patient's nasal bridge while aligning the tip of the bottle directly over a second eye. The bottle is then squeezed again to forcibly expel drops into the second eye.

A method of delivering safe, suitable, and repeatable dosages to a subject for topical, oral, nasal, or pulmonary use and a device for droplet ejection includes a fluid delivery system capable of delivering a defined volume of the fluid in the form of droplets having properties that afford adequate and repeatable high percentage deposition upon application. The method and device include a housing, a reservoir disposed within the housing for receiving a volume of fluid, an ejector mechanism configured to eject a stream of droplets having an average ejected droplet diameter greater than 15 microns, the stream of droplets having low entrained airflow such that the stream of droplets deposit on the eye of the subject during use.

An implant for insertion into a punctum of a patient comprises a body. The body has a distal end, a proximal end, and an axis therebetween. The distal end of the body is insertable distally through the punctum into the canalicular lumen. The body comprises a therapeutic agent included within an agent matrix drug core. Exposure of the agent matrix to the tear fluid effects an effective therapeutic agent release into the tear fluid over a sustained period. The body has a sheath disposed over the agent matrix to inhibit release of the agent away from the proximal end. The body also has an outer surface configured to engage luminal wall tissues so as to inhibit expulsion when disposed therein. In specific embodiments, the agent matrix comprises a non-bioabsorbable polymer, for example silicone in a non-homogenous mixture with the agent.

An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.

This application is related to a head-mounted display system and related methods for entertainment, diagnostics, and treatment. The HMD includes various sensors and tools to take physical measurements, perform physical procedures, adjust physical conditions, or manipulate digital data. In some embodiments, the HMD produces different types of sensory stimuli, such as releasing or filtering certain compounds in liquid or aqueous forms in the space near the HMD, or adjusting different physical features of the space near the HMD, such as temperature and flow, to enhance the augmented or virtual reality environment being displayed. In some embodiments, the HMD performs regular monitoring, a specific examination, a surgical intervention, or other care procedures on the eyes automatically or in conjunction with a device of an eye care professional across a computer network to care for the user's eyes in real time or on an ongoing basis.

A dispenser assembly includes a dispenser bottle having a nipple for dispensing a solution (e.g., eye drop solution, eye wash solution, eye lid cleaner and/or wash solution), and a cap removably couplable to the dispenser bottle over the nipple. An eye cup is fixedly coupled to the dispenser bottle around the nipple. The eye cup can be supported on or rest on the periphery of the eye socket to facilitate delivery of the solution onto or over a user's eye.

This disclosure provides an ophthalmological surgical device to perform amniotic membrane transplantation or internal limiting membrane transplantation to the macula of an eye of a subject. The device includes a handle portion; a rod-shaped body attached to one end of the handle portion; a brush portion made of materials capable of holding electrostatic charges attached to the distal end of the rod-shaped body. Making use of the triboelectric effect in static electricity, the brush will attract biological membranes such as the amniotic membrane and allow placement of the membrane over the macula or other desired retinal position with precision and ease.

Provided herein are devices and methods for delivering medical implants into a patient, such as intravitreally. In one exemplary implementation, an implant delivery device includes an elongated body, cannula, mandrel, front shuttle, dispense button and leaf spring. The cannula is carried by the body and configured to receive an implant. The mandrel is slidably received within the cannula. The front shuttle is coupled to the mandrel. The leaf spring has at least a portion that spans between the dispense button and the front shuttle. The delivery device is configured to be operated by a user moving the dispense button from an extended position to a depressed position, thereby deflecting the leaf spring and urging the front shuttle towards the distal end of the body and causing the mandrel to move from a retracted position to a distally advanced position to eject the implant from a distal portion of the cannula.

An assistance device for assisting with the use of a device for dispensing a liquid product in the form of drops having a tank including a connector for rigid connection to the dispensing device, an optical device arranged near a dispensing orifice, configured to provide information on the dispensing of a liquid drop by the dispensing device, a measuring device for measuring the inclination, configured to provide information on the inclination of the dispensing device connected to the assistance device, and a system for processing information on the dispensing of a drop and on the inclination of the dispensing device connected to the assistance device to provide information on the amount of liquid product dispensed. The invention also relates to a dispensing kit and a method for determining the amount of liquid product dispensed in the form of drops by a liquid-dispensing device, with the assistance device.

A method of delivering safe, suitable, and repeatable dosages to a subject for topical, oral, nasal, or pulmonary use and a device for droplet ejection includes a fluid delivery system capable of delivering a defined volume of the fluid in the form of droplets having properties that afford adequate and repeatable high percentage deposition upon application. The method and device include a housing, a reservoir disposed within the housing for receiving a volume of fluid, an ejector mechanism configured to eject a stream of droplets having an average ejected droplet diameter greater than 15 microns, the stream of droplets having low entrained airflow such that the stream of droplets deposit on the eye of the subject during use.