Systems and methods for medication management are provided. Some embodiments provide for a portable medication management and monitoring system for eye drop instillation in ocular chronic conditions. At least one embodiment includes a device having one or more of the following elements: (a) a jacket that goes around an eye drop bottle; (b) tactile sensors to detect the user's fingers and generate data to activate the system; (c) motion sensors to detect the motion of the medication bottle when it is grabbed and moved by the user; (d) a wireless communication module to send and receive data to a computer and portable communication devices; and/or (e) a compartment for holding the electronic components.

Injection devices for delivering pharmaceutical compositions into the eye are described. Some devices include a resistance component for controllably deploying an injection needle through the eye wall. The resistance component may be disposed on a removable injector attachment or on a portion of the injection device housing. Other devices may include a filter for the removal of air, infectious agents, and/or other particulate matter from the composition before the composition is injected into the eye. Related methods and systems comprising the devices are also described.

Injection devices for delivering pharmaceutical compositions into the eye are described. Some devices include a resistance component for controllably deploying an injection needle through the eye wall. The resistance component may be disposed on a removable injector attachment or on a portion of the injection device housing. Other devices may include a filter for the removal of air, infectious agents, and/or other particulate matter from the composition before the composition is injected into the eye. Related methods and systems comprising the devices are also described.

Device for packaging and dispensing drops of a substance for ophthalmic use, generally fluid, semi-fluid or in suspension, emulsion or oily solution including a dispensing accessory with a first valve made of an elastomer material that allows the substance to pass through when the dispensing accessory is stressed, without allowing outside air to pass through in the opposite direction when the dispensing accessory is relaxed, characterized in that the first valve is covered by a layer of Parylene.

In various embodiments, a drug-delivery device includes one or more reservoirs that may each contain a therapeutic agent for delivery to a patient.

Several embodiments disclosed herein relate to the delivery of therapeutic nucleic acids to an ocular tissue in order to provide a therapeutic effect to reduce symptoms of or otherwise alleviate an ocular disorder. In particular embodiments, plasmid DNA is delivered to the cells of the trabecular meshwork in order to ameliorate increasing intraocular pressure. Devices and systems to accomplish this delivery are also disclosed.

The present invention is a device that is used in squint surgeries which contains two parts: the first part is fixated to the insertion and the second part is fixated to the muscle/muscle tendon, and the two parts are connected to each other with two threads at both sides, in this device the distance between the two parts can be adjusted; hence the magnitude of muscle resection or recession. Also a new procedure (alternative to resection procedure) is provided; in which we shorten the muscle without resecting it. In addition to the main device, there is a tiny sclera screws that can fixate any device implanted on the sclera.

An ophthalmic laser ablation system is described with various optional features, some especially suitable for non-penetrating filtration on an eye. In one example, focusing of an ablation laser uses a movable lens coupled to a pair of converging light sources, which converge at the focal distance of the lens. In another example, laser ablation settings are selected for optimal ablation and minimal amount of thermal damage of a layer of percolating scleral tissue.

An applicator for applying fluid medicaments to a corneal surface of a patient, after surgery, includes a circular, ring-shaped member. The ring member creates an aperture which extends between parallel planes, with a wall surrounding the aperture as well as upper and lower openings into the aperture. The wall around the aperture is tapered, and there is a hole that extends through the wall. A hollow shaft is connected in fluid communication with the hole in the wall through which a fluid can be injected into the aperture. A bubble of the fluid can then be cradled in the aperture by the wall, and held therein by surface tension across the lower opening of the aperture. An application of the fluid bubble onto the patient's eye requires only contact between the fluid bubble and the eye, with no need for contact between the applicator and the eye.

An article for therapy and treatment of at least one eye. The article includes a backing for application to the at least one eye. The backing includes at least one receiver positioned to align with the at least one eye. The article also includes at least one pod that is detachably secured within the at least one receiver. The at least one pod includes material for delivering therapy and treatment to the at least one eye.