A dispenser assembly includes a dispenser bottle having a nipple for dispensing a solution (e.g., eye drop solution, eye wash solution, eye lid cleaner and/or wash solution), and a cap removably couplable to the dispenser bottle over the nipple. The dispenser bottle has a chamber that removably receives a single-use vial cartridge. An eye cup is fixedly coupled to the dispenser bottle around the nipple, or the eye cup is detachable and invertible relative to the dispenser bottle. The eye cup can be supported on or rest on the periphery of the eye socket to facilitate delivery of the solution onto or over a user's eye.

A system for tracking delivery of a medication to a users eye and a method of use. The system comprises at least one camera for capturing one or more images of an eye surface of the users eye before, during, and after a time when the medication is applied to the users eye. The images captured are visual or thermal images, and for example, a temperature of the eye, eyelid, and periocular surfaces may be captured as well as visualization of the location of the eyelid or iris. If a second camera is used, it may be the same or different type of camera as the first camera and may capture one or more second images of the users eye before, during, and after the time when the droplets of the medication are applied to the users eye. A processor is provided for comparing the first images captures and/or comparing the first images to the second images, in order to determine when to deploy the droplets and/or if the droplets of the medication were successfully applied to the users eye.

Disclosed are devices and methods for directed delivery of a medicament into ocular tissue. A device for delivering a medicament to ocular tissue may include a housing, a container configured to contain the medicament, and a needle in fluid communication with the container, and a carriage positioned within the housing and coupled to the container and the needle. The carriage may be translatable along the needle axis and the carriage may include a threaded outer surface. The device may further include a nut positioned within the housing and engaged with the threaded outer surface. Rotation of the nut may be configured to cause the carriage and the needle to translate in a distal direction along the needle axis.