Wearable system and method for gas delivery to the exterior surface of an eye. In one embodiment, the system may include a gas source and a wearable gas delivery device. The gas source may include a housing, one or more electrochemical gas generating devices positioned within the housing, and a control unit for controlling the operation of the one or more electrochemical gas generating devices. The one or more electrochemical gas generating devices may include an electrochemical oxygen concentrator and a water electrolyzer. Oxygen outputted from the electrochemical oxygen concentrator may be combined with oxygen and/or hydrogen outputted from the electrolyzer to produce a therapeutic gas having an enriched oxygen concentration and a hydrogen concentration less than 4%. The wearable gas delivery device, which is fluidly coupled to the gas source, may be worn over the eye and may be used to deliver the therapeutic gas to the eye.

Disclosed is an accommodating intraocular lens device for treatment of an eye including a stabilization haptic (120) configured to be positioned within a region of an eye and a lens body having a sealed chamber containing a fixed volume of optical fluid. The lens body includes a shape changing membrane (145) configured to outwardly bow in a region surrounding the optical axis of the eye; a shape deformation membrane configured to undergo displacement relative to the first shape changing membrane; and a static element (150). An inner surface of the shape changing membrane, an inner surface of the shape deformation membrane and an inner surface of the static element collectively form the sealed chamber. The lens device also includes a force translation arm (115) having a first end configured to contact an outer surface of the shape deformation membrane of the lens body and a second end configured to engage a ciliary structure of the eye. The force translation arm is configured to move relative to the lens body upon movement of the ciliary structure.

An apparatus includes a body, a needle, a catheter, and an actuator assembly. The needle extends distally from the body. The needle has an inner wall defining a needle lumen. The needle lumen is in fluid communication with a fluid port of the body. The catheter is slidably disposed in the needle lumen. The catheter has a catheter lumen. The first actuator assembly is configured to translate the catheter within and relative to the needle. The apparatus may also include an actuator assembly that is configured to rotate the needle relative to the body. The apparatus may be used to first deliver a leading bleb of fluid to the subretinal space in a patient's eye via the needle. The apparatus may then be used to deliver a therapeutic agent to the subretinal space in the patient's eye via the catheter.

Disclosed are devices and methods for delivering a sheet of tissue into the eye in such a way that damage to the tissue is minimized, damage to the eye during insertion and manipulation of the tissue is minimized, and the tissue is released and delivered in a precise and controlled fashion.

A fluid dispensing device includes a cartridge comprising a housing and a head coupled to the housing. The housing forms a first chamber configured to accommodate a fluid; and the head includes a nozzle; and an elastomeric wall that is spaced from the nozzle to form a holding chamber. The holding chamber is in fluid communication with the first chamber and configured to accommodate a portion of the fluid; and the nozzle forms one or more openings to eject the portion of the fluid from the holding chamber. The one or more openings form an oblong shape such that a length of the oblong shape is greater than a width of the oblong shape. The one or more openings can include two parallel slots that together form the oblong shape.

The present invention is a device for holding an ophthalmic bottle of drops and instilling them in a patient's eye. The device rests on the boney lower orbital ridge for stability and correct delivery.

Disclosed herein are improved dispensing devices for facilitating application of eye drops that are ergonomic, promote improved patient adherence, and eliminate the need for extraneous gadgets or facilitating devices that may add additional expense to users. A dispensing device can include a container body for storing drops and a nozzle coupled to the body for dispensing the drops. The device can include one or more channels defined on a surface of the container body and configured to couple, or otherwise mount or abut, to an anatomical structure of a user (such as, for example, a user's nose bridge or eyebrow ridge). The device can also include one or more grip areas defined on the container body and configured to allow a user to generally hold the device and to apply force thereto to dispense drops from the device.

Various implementations include a tissue lifting device that is operable using one hand. The device includes a housing, an actuator that is slidably moveable through a channel within the housing, and a lifting mechanism adjacent a distal end of the housing. The actuator causes the lifting mechanism to lift a tissue. In some implementations, the housing includes a needle adjacent the distal end of the housing that punctures the tissue and allows for injection of a composition behind the tissue. The lifting mechanism according to some implementations is a suction-based (or aspiration) system. And, in other implementations, the lifting mechanism is a grasping system.

One-piece adaptor device for the administration of ophthalmic drops, which comprises an elongate alignment area which forms an alignment body of the adaptor device for receiving a single-dose container of ophthalmic fluid, the alignment area also comprising at least one means for holding said container, a support attachment joined as an extension to the alignment body which terminates in an ergonomic distal end, suitable for resting on the lower area of the eyelid, which adapter device is characterised in that it contains at least one protrusion on the alignment body for pressing the container and facilitating the ophthalmic fluid to come out by pressure.

Multi-dose ocular fluid delivery devices are provided. Aspects of the fluid delivery devices include a fluid package and an actuator. The fluid package includes a reservoir of an ophthalmic formulation, an aperture and a valve member for sealing the aperture when fluid is not being ejected therethrough. The actuator is configured to operate the valve member so as to at least reduce, if not prevent, ingress of outside materials or contaminants into the reservoir, such that the ophthalmic formulation present in the reservoir does not require a preservative (e.g., where a preservative-free ophthalmic formulation is present in the reservoir). Also provided are methods of using the devices in fluid delivery applications, as well as a kit that includes components of the devices.